Triple Oxygen Isotope Composition of Carbonates

This dissertation presents a method of analyzing the triple oxygen isotope compositions of carbonates, presents an empirical calibration of the carbonate-water equilibrium fractionation line, presents a triple oxygen isotope equipped fluid-rock mixing model for carbonates to see-through diagenesis, and applies all these findings to ancient carbonate samples. Using modern carbonates and associate water, the following equations are calculated to describe equilibrium triple oxygen isotope fractionation of carbonates: 1000lnalpha18Occ-wt=2.84x106/T2-2.96 1), Thetacc-wt=-1.39/T+0.5305 2). Using these fractionation equations provides an extremely useful tool to determine whether a carbonate sample is altered or preserves its original isotopic composition. In samples that are altered, a fluid-rock mixing model is used to see-through the diagenesis. Applying these tools to ancient carbonate rocks shows that many samples thought to be pristine are altered and are confusing paleoenvironmental interpretations. This work shows that seawater temperature and isotopic composition is unchanged over the Phanerozoic, an important consideration when reconstruction paleoenvironments

Real measurements and Quantum Zeno effect

In 1977, Mishra and Sudarshan showed that an unstable particle would never be found decayed while it was continuously observed. They called this effect the quantum Zeno effect (or paradox). Later it was realized that the frequent measurements could also accelerate the decay (quantum anti-Zeno effect). In this paper we investigate the quantum Zeno effect using the definite model of the measurement. We take into account the finite duration and the finite accuracy of the measurement. A general equation for the jump probability during the measurement is derived. We find that the measurements can cause inhibition (quantum Zeno effect) or acceleration (quantum anti-Zeno effect) of the evolution, depending on the strength of the interaction with the measuring device and on the properties of the system. However, the evolution cannot be fully stopped.Comment: 3 figure

Scalar-Tensor Gravity and Quintessence

Scalar fields with inverse power-law effective potentials may provide a negative pressure component to the energy density of the universe today, as required by cosmological observations. In order to be cosmologically relevant today, the scalar field should have a mass $m_\phi = O(10^{-33} {\mathrm eV})$, thus potentially inducing sizable violations of the equivalence principle and space-time variations of the coupling constants. Scalar-tensor theories of gravity provide a framework for accommodating phenomenologically acceptable ultra-light scalar fields. We discuss non-minimally coupled scalar-tensor theories in which the scalar-matter coupling is a dynamical quantity. Two attractor mechanisms are operative at the same time: one towards the tracker solution, which accounts for the accelerated expansion of the Universe, and one towards general relativity, which makes the ultra-light scalar field phenomenologically safe today. As in usual tracker-field models, the late-time behavior is largely independent on the initial conditions. Strong distortions in the cosmic microwave background anisotropy spectra as well as in the matter power spectrum are expected.Comment: 5 pages, 4 figure

Aston University's Antimicrobial Resistance (AMR) Roadshow: raising awareness and embedding knowledge of AMR in key stage 4 learners:raising awareness and embedding knowledge of AMR in key stage 4 learners

Antimicrobial resistance (AMR) is a global healthcare problem and therefore raising awareness within young learners is imperative. An AMR roadshow was designed to take key stage 4 students' learning ‘out of the classroom’, assess pre-existing knowledge of AMR and determine the impact of the roadshow on knowledge retention. Knowledge and subsequent retention were measured pre- and post-event through a standardised questionnaire. The roadshow significantly improved knowledge and understanding of AMR, which was retained for a minimum of twelve weeks. Engaging and interactive strategies addressing key health issues provide a positive learning experience which contributes to retained knowledge in young learners

Particle creation in the effective action method

The effect of particle creation by nonstationary external fields is considered as a radiation effect in the expectation-value spacetime. The energy of created massless particles is calculated as the vacuum contribution in the energy-momentum tensor of the expectation value of the metric. The calculation is carried out for an arbitrary quantum field coupled to all external fields entering the general second-order equation. The result is obtained as a functional of the external fields. The paper gives a systematic derivation of this result on the basis of the nonlocal effective action. Although the derivation is quite involved and touches on many aspects of the theory, the result itself is remarkably simple. It brings the quantum problem of particle creation to the level of complexity of the classical radiation problem. For external fields like the electromagnetic or gravitational field there appears a quantity, the radiation moment, that governs both the classical radiation of waves and the quantum particle production. The vacuum radiation of an electrically charged source is considered as an example. The research is aimed at the problem of backreaction of the vacuum radiation.Comment: 129 pages including 7 figures. Latex 2.09. Figures by METAFONT, 300 DPI. Execute the file "arttotal.tex

Probe-configuration dependent dephasing in a mesoscopic interferometer

Dephasing in a ballistic four-terminal Aharonov-Bohm geometry due to charge and voltage fluctuations is investigated. Treating two terminals as voltage probes, we find a strong dependence of the dephasing rate on the probe configuration in agreement with a recent experiment by Kobayashi et al. (J. Phys. Soc. Jpn. 71, 2094 (2002)). Voltage fluctuations in the measurement circuit are shown to be the source of the configuration dependence.Comment: 4 pages, 3 figure

Stability of Circular Orbits in General Relativity: A Phase Space Analysis

Phase space method provides a novel way for deducing qualitative features of nonlinear differential equations without actually solving them. The method is applied here for analyzing stability of circular orbits of test particles in various physically interesting environments. The approach is shown to work in a revealing way in Schwarzschild spacetime. All relevant conclusions about circular orbits in the Schwarzschild-de Sitter spacetime are shown to be remarkably encoded in a single parameter. The analysis in the rotating Kerr black hole readily exposes information as to how stability depends on the ratio of source rotation to particle angular momentum. As a wider application, it is exemplified how the analysis reveals useful information when applied to motion in a refractive medium, for instance, that of optical black holes.Comment: 20 pages. Accepted for publication in Int. J. theor. Phy

Wave scattering from self-affine surfaces

Electromagnetic wave scattering from a perfectly reflecting self-affine surface is considered. Within the framework of the Kirchhoff approximation, we show that the scattering cross section can be exactly written as a function of the scattering angle via a centered symmetric Levy distribution for general roughness amplitude, Hurst exponent and wavelength of the incident wave. The amplitude of the specular peak, its width and its position are discussed as well as the power law decrease (with scattering angle) of the scattering cross section.Comment: RevTeX, 4 pages including 2 figures. Submitted Phys. Rev. Let

Classical and Quantum Nambu Mechanics

The classical and quantum features of Nambu mechanics are analyzed and fundamental issues are resolved. The classical theory is reviewed and developed utilizing varied examples. The quantum theory is discussed in a parallel presentation, and illustrated with detailed specific cases. Quantization is carried out with standard Hilbert space methods. With the proper physical interpretation, obtained by allowing for different time scales on different invariant sectors of a theory, the resulting non-Abelian approach to quantum Nambu mechanics is shown to be fully consistent.Comment: 44 pages, 1 figure, 1 table Minor changes to conform to journal versio

Common and low frequency variants in MERTK are independently associated with multiple sclerosis susceptibility with discordant association dependent upon HLA-DRB1*15:01 status

Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. The risk of developing MS is strongly influenced by genetic predisposition, and over 100 loci have been established as associated with susceptibility. However, the biologically relevant variants underlying disease risk have not been defined for the vast majority of these loci, limiting the power of these genetic studies to define new avenues of research for the development of MS therapeutics. It is therefore crucial that candidate MS susceptibility loci are carefully investigated to identify the biological mechanism linking genetic polymorphism at a given gene to the increased chance of developing MS. MERTK has been established as an MS susceptibility gene and is part of a family of receptor tyrosine kinases known to be involved in the pathogenesis of demyelinating disease. In this study we have refined the association of MERTK with MS risk to independent signals from both common and low frequency variants. One of the associated variants was also found to be linked with increased expression of MERTK in monocytes and higher expression of MERTK was associated with either increased or decreased risk of developing MS, dependent upon HLA-DRB1*15:01 status. This discordant association potentially extended beyond MS susceptibility to alterations in disease course in established MS. This study provides clear evidence that distinct polymorphisms within MERTK are associated with MS susceptibility, one of which has the potential to alter MERTK transcription, which in turn can alter both susceptibility and disease course in MS patients