20 research outputs found

    Controlling Phase Space Caustics in the Semiclassical Coherent State Propagator

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    The semiclassical formula for the quantum propagator in the coherent state representation is not free from the problem of caustics. These are singular points along the complex classical trajectories specified by z′\mathbf{z}', z′′\mathbf{z}'' and TT where the usual quadratic approximation fails, leading to divergences in the semiclassical formula. In this paper we derive third order approximations for this propagator that remain finite in the vicinity of caustics. We use Maslov's method and the dual representation proposed in Phys. Rev. Lett. {\bf 95}, 050405 (2005) to derive uniform, regular and transitional semiclassical approximations for coherent state propagator in systems with two degrees of freedom.Comment: 24 pages, to appear in Ann. of Phy

    A radar study of emigratory flight and layer formation by insects at dawn over southern Britain

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    Radar observations have consistently shown that high-altitude migratory flight in insects generally occurs after mass take-off at dusk or after take-off over a more extended period during the day (in association with the growth of atmospheric convection). In this paper, we focus on a less-studied third category of emigration – the ‘dawn take-off’ – as recorded by insect-monitoring radars during the summer months in southern England. In particular, we describe occasions when dawn emigrants formed notable layer concentrations centred at altitudes ranging from ca. 240m to 700m above ground, very probably due to the insects responding to local temperature maxima in the atmosphere, such as the tops of inversions. After persisting for several hours through the early morning, the layers eventually merged into the insect activity building up later in the morning (from 06.00–08.00 h onwards) in conjunction with the development of daytime convection. The species forming the dawn layers have not been positively identified, but their masses lay predominantly in the 16–32mg range, and they evidently formed a fauna quite distinct from that in flight during the previous night. The displacement and common orientation (mutual alignment) characteristics of the migrants are described

    Selective and Signal-dependent Recruitment of Membrane Proteins to Secretory Granules Formed by Heterologously Expressed von Willebrand Factor

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    von Willebrand factor (vWF) is a large, multimeric protein secreted by endothelial cells and involved in hemostasis. When expressed in AtT-20 cells, vWF leads to the de novo formation of cigar-shaped organelles similar in appearance to the Weibel-Palade bodies of endothelial cells in which vWF is normally stored before regulated secretion. The membranes of this vWF-induced organelle, termed the pseudogranule, are uncharacterized. We have examined the ability of these pseudogranules, which we show are secretagogue responsive, to recruit membrane proteins. Coexpression experiments show that the Weibel-Palade body proteins P-selectin and CD63, as well as the secretory organelle membrane proteins vesicle-associated membrane protein-2 and synaptotagmin I are diverted away from the endogenous adrenocorticotropic hormone-containing secretory granules to the vWF-containing pseudogranules. However, transferrin receptor, lysosomal-associated membrane protein 1, and sialyl transferase are not recruited. The recruitment of P-selectin is dependent on a tyrosine-based motif within its cytoplasmic domain. Our data show that vWF pseudogranules specifically recruit a subset of membrane proteins, and that in a process explicitly driven by the pseudogranule content (i.e., vWF), the active recruitment of at least one component of the pseudogranule membrane (i.e., P-selectin) is dependent on residues of P-selectin that are cytosolic and therefore unable to directly interact with vWF
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