53,208 research outputs found
Malignant peripheral nerve sheath tumour: A rare tumour of the breast
Malignant peripheral nerve sheath tumour is a rare tumour of the breast and this report highlights the radiological and histological features and the difficulties in making a diagnosis. A high index of suspicion when dealing with a breast lesion that has both cystic and solid components in a background of von Recklingausen’s neurofibromatosis will make the diagnosis easie
Human behavior in Prisoner's Dilemma experiments suppresses network reciprocity
During the last few years, much research has been devoted to strategic
interactions on complex networks. In this context, the Prisoner's Dilemma has
become a paradigmatic model, and it has been established that imitative
evolutionary dynamics lead to very different outcomes depending on the details
of the network. We here report that when one takes into account the real
behavior of people observed in the experiments, both at the mean-field level
and on utterly different networks the observed level of cooperation is the
same. We thus show that when human subjects interact in an heterogeneous mix
including cooperators, defectors and moody conditional cooperators, the
structure of the population does not promote or inhibit cooperation with
respect to a well mixed population.Comment: 5 Pages including 4 figures. Submitted for publicatio
Temporal HeartNet: Towards Human-Level Automatic Analysis of Fetal Cardiac Screening Video
We present an automatic method to describe clinically useful information
about scanning, and to guide image interpretation in ultrasound (US) videos of
the fetal heart. Our method is able to jointly predict the visibility, viewing
plane, location and orientation of the fetal heart at the frame level. The
contributions of the paper are three-fold: (i) a convolutional neural network
architecture is developed for a multi-task prediction, which is computed by
sliding a 3x3 window spatially through convolutional maps. (ii) an anchor
mechanism and Intersection over Union (IoU) loss are applied for improving
localization accuracy. (iii) a recurrent architecture is designed to
recursively compute regional convolutional features temporally over sequential
frames, allowing each prediction to be conditioned on the whole video. This
results in a spatial-temporal model that precisely describes detailed heart
parameters in challenging US videos. We report results on a real-world clinical
dataset, where our method achieves performance on par with expert annotations.Comment: To appear in MICCAI, 201
Quantitative chemical analysis of perovskite deposition using spin coating
Lead and halide ion compositions of spin coated organo-lead halide perovskite films have been quantified
using ion chromatography (IC) and atomic absorption spectroscopy (AAS) using perovskite films manufactured
by 5 different researchers (3 replicates per treatment) to monitor variability between researchers
and individual researcher reproducibility. Planar and mesoporous TiO2-coated glass substrates have
been studied along with tribromide (CH3NH3PbBr3), triiodide (CH3NH3PbI3) and mixed halide
(CH3NH3PbI3�xClx) perovskite films. The data show low yields of spin coated perovskite material (ca.
1%) and preferential deposition of I� over Cl� in mixed halide films
Mathematical modelling of the pathogenesis of multiple myeloma-induced bone disease
Multiple myeloma (MM) is the second most common haematological malignancy and results in destructive bone lesions. The interaction between MM cells and the bone microenvironment plays an important role in the development of the tumour cells and MM-induced bone disease and forms a 'vicious cycle' of tumour development and bone destruction, intensified by suppression of osteoblast activity and promotion of osteoclast activity. In this paper, a mathematical model is proposed to simulate how the interaction between MM cells and the bone microenvironment facilitates the development of the tumour cells and the resultant bone destruction. It includes both the roles of inhibited osteoblast activity and stimulated osteoclast activity. The model is able to mimic the temporal variation of bone cell concentrations and resultant bone volume after the invasion and then removal of the tumour cells and explains why MM-induced bone lesions rarely heal even after the complete removal of MM cells. The behaviour of the model compares well with published experimental data. The model serves as a first step to understand the development of MM-induced bone disease and could be applied further to evaluate the current therapies against MM-induced bone disease and even suggests new potential therapeutic targets
Dietary aflatoxin exposure and impaired growth in young children from Benin and Togo: cross sectional study
Fetal and early childhood environment, including the
nutritional status of the pregnant mother and the
infant, are considered critical for growth and risk of
disease in later life. Many people in developing coun
tries are not only malnourished but also chronically
exposed to high levels of toxic fungal metabolites
(mycotoxins). One family of mycotoxins, the aflatoxins,
are carcinogenic and immunotoxic and cause growth
retardation in animals. Aflatoxins contaminate staple
foods in West Africa, particularly maize and ground
nuts, as a result of hot, humid storage conditions that
promote fungal growth. High exposure to aflatoxins
occurs throughout childhood in the region, suggest
ing that growth and development could be critically
affected.We assessed exposure to aflatoxins in relation
to anthropometric measures in children in Benin and
Togo
Student Teachers’ Perceptions about Their Experiences in a Student Centered Course
There is a growing need to provide curricula that meets the changing needs of students in higher education. To trainpre-service teachers according to the demands of the new educational contexts, the move from teacher-centered curricula to learning-centered curricula is a must. The aim of this research is to examine the currently used curriculum of EGIT 450 Student Centered Education (SCE) course to highlight suggestions for a better design and implementation of the SCE approach. A qualitative paradigm was used with an interpretive methodology. The participants of the study were the 37 third year undergraduate students enrolled in the course at one of the tertiary institutions in North Cyprus. Qualitative data were collected through end-of-the-semester reflective essays and analyzed through content analysis method. The findings revealed that SCE methodology helped improve student teachers’ cognitive skills via holding an active role and their affective skills through group work activities emphasizing its effect on permanent learning and learning how to learn. Participants also pointed out the difficulty and complexity of the roles expected from the teacher and learners individually and cooperatively. The inefficiency of some of the teaching-learning activities, physical characteristics of the classroom setting and duration of the allocated time for the activities were among the weak aspects of the course.Keywords: affective skills, course design, cognitive skills, curriculum design, student centered educatio
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