Associated data on the physicochemical properties of pedosediments, climatic and dendrochronological indicators for palaeogeographic reconstructions

Palaeogeographic markers can be justified among a large number of geochemical indicators in separate layers of pedosediments. Using individual of macroelements and trace elements as part of complex geochemical relationships and indicators allows us to determine the geochemical associations of elements that diagnose migration of the sediments at the trans-eluvial catena

Effects of dimephosphone on skin survival in conditions of reduced blood circulation

The search for and creation of drugs with dermatoprotective and metabotropic activity is one of the priorities of modern diabetology. Synthetic organophosphorus compounds with no anticholinesterase activity, to which dimephosphone belongs to, deserve great attention in this respec

ИЗМЕНЕНИЕ ФУНКЦИЙ ЯЗЫКА В СОВРЕМЕННОЙ ЛИНГВИСТИЧЕСКОЙ ПАРАДИГМЕ: ВЛИЯНИЕ ВИРТУАЛЬНОГО ДИСКУРСА

The modern linguistic paradigm in its conceptual and epistemological content represents a multi-subject system of directions united by a single methodological dominant of anthropocentrism. The priority of the anthropocentric projection in the description of the natural human language is due to the dialectic process of accumulation of linguistic knowledge, which predetermined a qualitatively new understanding of the ontology of the object under study. The principle of anthropocentrism determines the broad explanatory capabilities of modern linguistics in establishing constant units and categories mediated by the gnoseological unity of language and human. The study of the perception of verbal texts takes place within the framework of individual linguistic disciplines: text linguistics, grammar, stylistics, and psycholinguistics. However, most studies of speech messages are conducted in the context of the idealization of the object, that is, isolation from the specific situation in which the speech message is perceived. If we consider the actual functioning of a speech message, then almost always there will be a phenomenon of creolization of the verbal text. In reality, voice communication is a creolized text representing a fusion of verbal text and non-linguistic means, which include the extra-linguistic situation and paralinguistic means of oral and written speech.El paradigma lingüístico moderno en su contenido conceptual y epistemológico representa un sistema de direcciones de múltiples sujetos unidos por un único método metodológico dominante del antropocentrismo. La prioridad de la proyección antropocéntrica en la descripción del lenguaje humano natural se debe al proceso dialéctico de acumulación de conocimiento lingüístico, que predeterminó una comprensión cualitativamente nueva de la ontología del objeto en estudio. El principio del antropocentrismo determina las amplias capacidades explicativas de la lingüística moderna para establecer unidades y categorías constantes mediadas por la unidad gnoseológica del lenguaje y el ser humano. El estudio de la percepción de los textos verbales se lleva a cabo dentro del marco de las disciplinas lingüísticas individuales: lingüística del texto, gramática, estilística y psicolingüística. Sin embargo, la mayoría de los estudios de mensajes de voz se realizan en el contexto de la idealización del objeto, es decir, el aislamiento de la situación específica en la que se percibe el mensaje de voz. Si consideramos el funcionamiento real de un mensaje de voz, casi siempre habrá un fenómeno de creolización del texto verbal. En realidad, la comunicación de voz es un texto creolizado que representa una fusión de texto verbal y medios no lingüísticos, que incluyen la situación extralingüística y los medios paralingüísticos del habla oral y escrita.Современная лингвистическая парадигма в своем концептуальном и эпистемологическом содержании представляет собой многосубъектную систему направлений, объединенных единой методологической доминантой антропоцентризма. Приоритет антропоцентрической проекции в описании естественного человеческого языка обусловлен диалектическим процессом накопления лингвистических знаний, предопределившим качественно новое понимание онтологии изучаемого объекта. Принцип антропоцентризма определяет широкие объяснительные возможности современной лингвистики в установлении постоянных единиц и категорий, опосредованных гносеологическим единством языка и человека.  Изучение восприятия вербальных текстов происходит в рамках отдельных лингвистических дисциплин: лингвистики текста, грамматики, стилистики, психолингвистики. Однако большинство исследований речевых сообщений проводится в контексте идеализации объекта, то есть изоляции от конкретной ситуации, в которой воспринимается речевое сообщение. Если рассматривать реальное функционирование речевого сообщения, то почти всегда будет иметь место явление креолизации вербального текста. В действительности речевая коммуникация представляет собой креолизованный текст, представляющий собой сплав вербального текста и неязыковых средств, к которым относятся экстралингвистическая ситуация и паралингвистические средства устной и письменной речи

Языковые особенности жанра легенд как основы технологии сторителлинга в рекламном дискурсе

Modern world life dictates its own rules and procedures also with respect to advertising. But how is it possible to attract attention of a potential buyer, to maximally interest him in products or services? The answer is pretty simple. People’s purchases base on their inner convictions and preferences, which, in turn, are generated by information received from outside. Organizations involved in the production and provision of services have long understood this pattern. This is what can justify the emergence of such a linguistic phenomenon as «storytelling». Research experts and experience in the field of advertising proved effectiveness of its application. It should be noted that the storytelling technology is based on the legend genre. In other words, in order for potential buyers to have an interest in relation to the consumption of a certain type of product or service, they should be as interested as possible by presenting relevant information. The legend used for this is nothing more than a narration about a product or service in a somewhat embellished form, aimed at influencing the target audience. In order for the legend, as the basis of the storytelling technology in advertising, to succeed, it is necessary that it meets certain language requirements. It should be emotional, bright, rich, etc. Urgency of the problem associated with the study of topics, voiced in the subject of the article, is justified by topicality of the studied issue, its influence on the life of society.La vida del mundo moderno dicta sus propias reglas y procedimientos también con respecto a la publicidad. Pero, ¿cómo es posible atraer la atención de un comprador potencial para que le interese al máximo en productos o servicios? La respuesta es bastante simple. Las compras de personas se basan en sus convicciones y preferencias internas, que, a su vez, son generadas por la información recibida del exterior. Las organizaciones involucradas en la producción y provisión de servicios han entendido por mucho tiempo este patrón. Esto es lo que puede justificar la aparición de un fenómeno tan lingüístico como la «narración de historias». Los expertos en investigación y la experiencia en el campo de la publicidad proporcionan la efectividad de su aplicación. Cabe señalar que la tecnología de narración se basa en el género de leyenda. En otras palabras, para que los compradores potenciales tengan interés en relación con el consumo de un determinado tipo de producto o servicio, deben estar lo más interesados posible al presentar la información relevante. La leyenda utilizada para esto no es más que una narración sobre un producto o servicio en una forma un tanto embellecida, dirigida a influir en el público objetivo. Para que la leyenda, como la base de la tecnología de narración en publicidad, tenga éxito, es necesario que cumpla con ciertos requisitos lingüísticos. Debe ser emocional, brillante, rico, etc. La urgencia del problema asociado al estudio de temas, expresado en el tema del artículo, justificado por la actualidad del tema estudiado, su influencia en la vida de la sociedad.Современная мировая жизнь диктует свои правила и процедуры и в отношении рекламы. Но как можно привлечь внимание потенциального покупателя, максимально заинтересовать его товарами или услугами? Ответ довольно прост. Покупки людей основываются на их внутренних убеждениях и предпочтениях, которые, в свою очередь, порождаются информацией, полученной извне. Организации, занимающиеся производством и оказанием услуг, давно поняли эту закономерность. Именно этим можно обосновать появление такого лингвистического феномена, как «сторителлинг». Исследования специалистов и опыт работы в области рекламы доказали эффективность ее применения. Следует отметить, что технология повествования основана на жанре легенды. Другими словами, для того чтобы потенциальные покупатели имели интерес в отношении потребления определенного вида продукции или услуги, они должны быть максимально заинтересованы в представлении соответствующей информации. Используемая для этого легенда-не более чем повествование о товаре или услуге в несколько приукрашенной форме, направленное на воздействие на целевую аудиторию. Для того чтобы легенда, как основа технологии повествования в рекламе, имела успех, необходимо, чтобы она отвечала определенным языковым требованиям. Оно должно быть эмоциональным, ярким, насыщенным и т. д. Актуальность проблемы, связанной с изучением тем, озвученных в теме статьи, обосновывается актуальностью изучаемого вопроса, его влиянием на жизнь общества

Effect of benzofurocainum on blood microcirculation in the attached gum in conditions of sound parodentium and experimental periodontitis

It was found that during the experiments on rats assisted by the Doppler flowmetering method the benzofurocainum (BF) lowers the erythrocyte flow and its fluctuation in the capillary race of the attached gum (AG) of the lower incisors by the intraperitoneal introduction in the dosage of 10 mg/kg in conditions of sound parodentium during 40 min (most evidently on the 10th min). In addition the vasomotor activity remains stable in comparison with the initial one, that can be conditioned by the increase of the general peripheric vessel resistance. In conditions of experimental periodontitis (EP) the blood microcirculation (BMC) in AG undergoes essential changes to lowering. The use of the traditional medicamental therapy (TMT) against the background of EP causes the increment in BMC in the chosen area after 12 days of treatment; one month later BMC decreases. The combination ТМТ + BF in taken conditions of the experiment induces the increment in BMC immediately after the treatment as well as one month after the use, besides BMC reaches the initial level

The influence of the vagus nerve and indole derivative SS-68 on excitation processes in the SA node

The aim of the study was to identify the components of the takeover process of central rhythmogenesis by the SA node in the conditions of atrial fibrillation when stimulating the vagus nerve and using substance SS-6

Changes of Granite Rapakivi under the Biofouling Influence

Interdisciplinary study of granite rapakivi biofouling in the natural and anthropogenic environment (St. Petersburg, Vyborg, Southern Finland) was carried out. The biodiversity of microorganisms (cyanobacteria, micromycetes, and organotrophic bacteria) and various types of biofilms are characterized. The influence of external factors on the changes of cyanobacterial biofilms is shown. The features of biofilms localization on the granite surface in an urban environment and in natural outcrops are studied. Differences in the biofilms metabolites composition at the granite quarries and monuments of St. Petersburg are shown. The behavior of chemical elements during the bioweathering of granite is estimated. The role of biofilms in the accumulation of chemical elements on the surface of granite is established. The dynamics of chemical elements leaching from granite may depend on the type of biofilm developing on granite

Comparative investigation of dimephosphon, actovegin and trental influence on survival potention of skin-fascial autograft in arterial blood insufficiency and venous stasis

It has been demonstrated that dimephosphon as well as actovegin and trental taken for the comparison in conditions of the «normal» (АВВА) arterialvenous permeability, «separated» (АВВА and АВВА; the underlined letters here and further denote the ligation of arteries and veins in different variants) and «mixed» (АВВА, АВВА, АВВА и АВВА) arterial and venous insuffieciency of the constrained skin-fascial autograft (on two feeding cruses with preserved skin sensitive nerves) increase its survival potential. On intensity of dermaprotective action (DPA) dimephosfon and reference preparations can be situated as following: АВВА - trental > dimephosphon = actovegin; АВВА - dimephosphon = trental > actovegin; АВВА - actovegin = dimephosphon, trental is not effective; АВВА - dimephosphon = actovegin = trental; АВВА - all these preparations are not effective; АВВА - trental > dimephosphon = actovegin. The DPA mechanism of dimephosphon depends on its ability to join in the different links of homeostasis and mediately to provide the functional correction of violated local (myogenic and metabolic) and remote neurohormonal mechanisms that regulate blood flow to the skin

The effect of zinc complex of N-isopropenylimidazole on the morphological characteristics of gum tissues in experimental endodontic-periodontal lesions in rats Authors

Introduction: Combined inflammatory and destructive processes affecting the dental pulp and tissues of the periodontal complex are among the most problem diseases of the dental system. Current therapy with use of available pharmacological agents does not always allow achieving the expected positive result. In addition, often the lack of information about morphological processes in the tissues of the dental system, in particular the gums, with endodontic-periodontal lesion (EPL) limits the ability of dentists to carry out targeted pharmacotherapy with both traditional and, in particular, new medications. The aim of the study was to evaluate the morphological characteristics of gum tissues in a therapeutic context of N-isopropenylimidazole zinc complex derivative in experimental endodontic-periodontal lesion in rats. Materials and Methods: A simulation of EPL in rats was performed in two ways: simultaneous induction of acute periodontitis and parodontitis by pulp extraction and natural infection of the pulp cavity, as well as by ligation of the necks of lower incisors. The research protocols included 5 groups of animals: 1st – intact group (control-1); 2nd – animals with simulated EPL (control-2); 3rd – animals with simulated EPL and treated with Metrogyl Denta® gel (M-D); 4th – animals with simulated EPL and treated with N–isopropenylimidazole zinc complex derivative gel under the laboratory code Pilim-1; and 5th – animals with simulated EPL and treated with the combination of M-D + Pilim-1. The gum of the lower incisors was taken for morphological studies. Slides were stained with hematoxylin and eosin. Computer morphometry was performed using the ImageJ software. Results and Discussion: The substances M-D, Pilim-1 and, especially, the combination of M-D+Pilim-1 (against the background of chlorhexidine bigluconate used as oral rinse) for 14 days in rats with simulated EPL cause a significant improvement of the morphological structure of the gum with minimal residual dystrophy and sclerosis. The combination M-D + Pilim-1 led to a 1.3-time increase in epithelial thickness, and a 1.5-time decrease in acanthosis depth in comparison with M-D, while the number of capillaries and their diameter had no significant differences. Compared with Pilim-1, the epithelial thickness increased 1.5 times, and the acanthosis depth and the number of capillaries decreased 1.6 and 1.4 times, respectively, whereas the diameter of the capillaries did not change significantly. The pronounced protective effect of the combination M-D + Pilim-1 on the morphological structure of the gingival mucosa of rats with simulated EPL may be associated with antimicrobial, anti-inflammatory, regenerating, angioprotective and antioxidant properties of both M-D and Pilim-1 separately, and, possibly to a greater extent, of the combination M-D + Pilim-1. Conclusion: The substances M-D, Pilim-1 and, especially, the combination M-D + Pilim-1 (against the background of chlorhexidine bigluconate used as oral rinse) for 14 days in rats with simulated EPL have a protective effect on the epithelial structure and the connective tissue of the proper mucous plate, manifested in active normalization of pathological changes and significant restoration of their organotypic structure