Differentiation of the regions of the central federal district of the Russian Federation according to the level of competitive advantages

The article reveals the methodology of competitive positioning of the regions, based on the clustering of the initial key competitive indicators, including those reflecting the regional resource potentia

Combustion and agglomeration of aluminized high-energy compositions

The results of combustion study for high-energy compositions (HECs) based on ammonium perchlorate (AP), butadiene rubber and ultrafine powder (UFP) aluminum Alex, and agglomeration of metal particles on the burning surface and composition of condensed combustion products (CCPs) are presented. It was found that partial replacement 2 wt. % of Alex by iron UFP in HEC increases the burning rate 1.3-1.4 times at the range of nitrogen pressure 2.0-7.5 MPa and reduces the mean diameter of CCPs particles d[43] from 37.4 [mu]m to 33.5 [mu]m at pressure [mu]4 MPa. Upon partial replacement 2 wt. % of Alex by boron UFP in HEC the recoil force of gasification products outflow from burning surface is increased by 9 % and the burning rate of HEC does not change in the above pressure range, while the mean diameter of CCPs particles is reduced to 32.6 [mu]m at p~4 MPa

Aseguramiento de protección contra el fuego en complejos industriales de agrupaciones animales

Aquí se presenta el estudio del aseguramiento de la protección contra el fuego en edificios agrupados de un conjunto de ganadería por medio de optimizar las medidas legislativas respectivas y analizar las influencias en la calidad y fiabilidad de los resultados de evaluar riesgos de incendio. Se llevaron a cabo los estudios a través de hacer valoración profesional, calcular riesgos de incendio individuales y simular la evacuación de la gente en el modelo de flujos humanos individual y en cadena. Los aspectos funcionales conceptuales de los edificios del conjunto resultaron en la necesidad de desarrollar soluciones técnicas y estructurales que podrían ayudar a reducir gastos ineficientes y armonizarían los edificios con las exigencias de la protección contra el fuego. El riesgo de incendios individual para los trabajadores del objeto de protección considerado es 2.91x10-7 por año-1 (0.291x10-6 por año), es decir, no sobrepasa el nivel normal establecido por la ley Federal 123-FZ del 22 de Julio de 2008 «Regulaciones Técnicas de las Exigencias a la Protección contra el Fuego". La adopción en el nivel legislativo del sistema de valorar riesgos de incendio creó para los dueños de objetos la oportunidad de optimizar los gastos para asegurar la protección contra el fuego, incluyendo el aseguramiento del nivel exigido de seguridad human

Aseguramiento de protección contra el fuego en complejos industriales de agrupaciones animales

This study deals with ensuring fire safety in buildings of a cluster animal industrial complex by optimizing legislative measures and analyzing factors that affect the quality and reliability of the results of calculating fire risk. The research involved the following methods: expert assessment; calculating individual fire risk; modeling evacuation of people in the form of an individual flow model of human traffic. The conceptual features of the complex's buildings required developing the design and technical solutions that would reduce inefficient costs on the one hand, and, on the other, would ensure meeting fire safety requirements. The individual fire risk for employees of the asset to be protected is 2.91 ×10-7 per year-1 (0.291 ×10-6 per year). That is, it does not exceed the characteristic value established by Federal law No. 123-FZ dated 22.07.2008 'Technical regulations on fire safety'. After the introduction of the fire risk assessment system at the legislative level, the owners of objects have received the opportunity to optimize the cost of fire safety and the required level of human safety.Aquí se presenta el estudio del aseguramiento de la protección contra el fuego en edificios agrupados de un conjunto de ganadería por medio de optimizar las medidas legislativas respectivas y analizar las influencias en la calidad y fiabilidad de los resultados de evaluar riesgos de incendio. Se llevaron a cabo los estudios a través de hacer valoración profesional, calcular riesgos de incendio individuales y simular la evacuación de la gente en el modelo de flujos humanos individual y en cadena. Los aspectos funcionales conceptuales de los edificios del conjunto resultaron en la necesidad de desarrollar soluciones técnicas y estructurales que podrían ayudar a reducir gastos ineficientes y armonizarían los edificios con las exigencias de la protección contra el fuego. El riesgo de incendios indivudual para los trabajadores del objeto de protección considerado es 2.91x10-7 por año-1 (0.291x10-6 por año), es decir, no sobrepasa el nivel normal establecido por la ley Federal 123-FZ del 22 de Julio de 2008 «Regulaciones Técnicas de las Exigencias a la Protección contra el Fuego». La adopción en el nivel legislativo del sistema de valorar riesgos de incendio creó para los dueños de objetos la oportunidad de optimizar los gastos para asegurar la protección contra el fuego, incluyendo el aseguramiento del nivel exigido de seguridad humana

The surgical treatment of destructive pulmonary tuberculosis in patients with diabetes

The purpose of the study was to improve quality of surgical treatable of destructive pulmonary tuberculosis in patients with diabetes.Materials and Methods. D.B. Giller and employees of the Department of Phthisiopulmonology and Thoracic Surgery of the First Moscow State Medical University M.I. Sechenov performed operations on 200 patients with diabetes due to tuberculosis. Group 1 was mustered from 78 patients from 2004 to 2009. Group 2 was mustered from 122 patients from 2011 to 2017.Results. An analysis of the results showed that after 31 operations, 27 (13.5%) patients from both groups developed 33 complications. The second group (6.6%) had fewer complications after surgery than the first group (24.4%) 3.7 times. The first group had more vulnerary and bronchopleural complications than the second group. 12 patients (15.4%) of the first group and 6 patients (4.9%) of the second group had bronchopleural complications (empyema, residual cavity, delayed expansion of the lung and intrapleural bleeding). 2 patients died in the hospital (30-day mortality was 0.66%) after 303 surgical intervention in both groups. 1 patient (0.9%) died after 106 surgical interventions in the first group. 1 patient (0.5%) died after 197 surgical interventions in the second group. The full effect was achieved in 75 (96.2%) patients in the first group and 114 (93.4%) in the second group. The survival value of patients of the second group was 100% after 1 year, 98% after 2 years, 98.8% after 3 years, 96.9% after 4 years, 95.2% after 5 years. The surgical treatable affected the occupational rehabilitation of patients from group 2. 61.5% of patients from group 2 became able to work after 1 year. 64.5% of patients from group 2 became able to work after 5 years.Conclusion. If doctors use our tactics in patients with destructive pulmonary tuberculosis and diabetes, the risk of complications after surgery will drop and reactivation of tuberculosis will not occur

Fluctuating Asymmetry of Measurable Parameters in Rana arvalis : Methodology

72 Fluctuating asymmetry (FA), i.e., undirected deviations from bilateral symmetry, of both measurable and nonmeasurable characteristics reflects ontogenetic instability, which some authors believe increases in response to genomic or environmental stress. This allows FA to be used for estimating the state of anthropogenically affected natural populations (e.g., Rana arvalis young of the year were captured on August 4 and 5, 2003, in the Kalinovskie Razrezy Park Forest in northern Yekaterinburg ( n = 26) and near the Yuzhnaya Bus Terminal ( n = 15), respectively. Ponds existing in the park forest had resulted from flooding desolate quarries. The vegetation was a herb-grass pine forest containing small shrubs. The results of our hydrochemical analyses performed in 2003 indicate that, according to the ecological sanitary classification of the quality of surface waters suggested by We measured the size parameters of the body that are standard for amphibians The results of the measurements shown in the table indicate that storage in the fixative led to a slight decrease in the mean values of most parameters measured in frogs from both populations. This decrease was the largest (and statistically significant) for the lengths of the thigh, crus, and temporal spot, i.e., the measurements at least partly involving soft tissue (F = 11.13-144.32, d.f. = 1/25 or 1/14, P = 0.004-0.0001 for the results of ANOVA with factors individual, body side

БЛОКЧЕЙН бИТКОИН: Типология участников

The paper describes the classification and criteria for blockchain environment participants. The overview of the main types of blockchain participants is essential for the understanding of blockchain social and economic behaviour. It structured in the description of the several patterns which is often generated inside the Bitcoin blockchain and the list of the economic entities with the criteria of their behaviour. The paper gives the view on the different types of blockchain entities both from outside and inside the blockchain. Also, the paper lists the possible risks of criminal behaviour corresponding to every entity.El artículo describe la clasificación y los criterios para los participantes del entorno de blockchain. La descripción general de los principales tipos de participantes de blockchain es esencial para la comprensión del comportamiento social y económico de blockchain. Se estructura en la descripción de los diversos patrones que a menudo se generan dentro de la cadena de bloques de Bitcoin y la lista de las entidades económicas con los criterios de su comportamiento. El documento ofrece una vista de los diferentes tipos de entidades de blockchain tanto desde fuera como desde dentro de blockchain. Además, el documento enumera los posibles riesgos de comportamiento criminal que corresponden a cada entidad.В статье описывается классификация и критерии классификации участников блокчейн среды. Обзор основных видов блокчейн участников имеет важное значение для понимания социального и экономического поведения в блокчейн. Статья структурирована как описание нескольких моделей, которые часто возникают внутри блокчейн Биткоин и перечень хозяйствующих субъектов с критериями их поведения. В статье дается представление о различных типах блокчейн структур со взглядом как снаружи, так и внутри блокчейн. Кроме того, в документе перечислены возможные риски преступного поведения, соответствующего каждому объект

OPTIMIZATION OF ELECTRONIC EQUIPMENT CONSIDERING ELECTROMAGNETIC COMPATIBILITY

The article discusses the main questions and the criteria for the optimization of electronic equipment considering electromagnetic compatibility

Systematic dissection of biases in whole-exome and whole-genome sequencing reveals major determinants of coding sequence coverage

Advantages and diagnostic effectiveness of the two most widely used resequencing approaches, whole exome (WES) and whole genome (WGS) sequencing, are often debated. WES dominated large-scale resequencing projects because of lower cost and easier data storage and processing. Rapid development of 3(rd) generation sequencing methods and novel exome sequencing kits predicate the need for a robust statistical framework allowing informative and easy performance comparison of the emerging methods. In our study we developed a set of statistical tools to systematically assess coverage of coding regions provided by several modern WES platforms, as well as PCR-free WGS. We identified a substantial problem in most previously published comparisons which did not account for mappability limitations of short reads. Using regression analysis and simple machine learning, as well as several novel metrics of coverage evenness, we analyzed the contribution from the major determinants of CDS coverage. Contrary to a common view, most of the observed bias in modern WES stems from mappability limitations of short reads and exome probe design rather than sequence composition. We also identified the similar to 500kb region of human exome that could not be effectively characterized using short read technology and should receive special attention during variant analysis. Using our novel metrics of sequencing coverage, we identified main determinants of WES and WGS performance. Overall, our study points out avenues for improvement of enrichment-based methods and development of novel approaches that would maximize variant discovery at optimal cost

Association of polymorphism rs10841855 in the glycogen synthase 2 gene with hypercholesterolemia and type 2 diabetes mellitus

The aim of the study: To investigate the association of polymorphism rs10841855 (G>T) GYS2 with the risk of T2D in residents of Central Russiaassessmen