Systematization of climate data in the virtual research environment on the basis of ontology approach

The first version of a primitive OWL-ontology of collections climate and meteorological data of Institute of Monitoring of Climatic and Ecological Systems SB RAS is presented. The ontology is a component of expert and decision support systems intended for quick search for climate and meteorological data required for solution of a certain class of applied problems

MESENCHYMAL STROMAL CELLS IN CORRECTION OF NEUROLOGICAL DEFICIT AND MORPHOLOGICAL CHANGES IN THE RAT MODEL OF FOCAL CEREBRAL LESIONS INDUCED BY VENOUS BLOOD FLOW DISORDER

The paper presents the results of assessing the effect of bone marrow-derived mesenchymal stromal cells (MSCs) on the severity of neurological deficit and the brain morphology and function in a model of focal lesions induced by a venous blood flow disorder. Cerebral lesions were induced in Wistar rats by coagulation of the superior sagittal sinus followed by coagulation of cortical veins in the left parietotemporal region. MSCs were injected intravenously on days 1 and 7, and the dynamics of neurological disorders and morphological changes were assessed at 7, 14 and 21 days in comparison to controls. MSCs infusion was accompanied by a significant reduction. in neurological deficit, the most pronounced with MSCs injections on day 1. Morphological investigation of the damaged region have shown that the administration of MSCs led to a decrease in the area of necrosis, stimulation of angiogenesis, and improvement of structural and cellular parameters as compared to the control group. As a result, by day 21 the area of necrosis in animals with MSC transplantation was replaced by glial-mesodermal scar, whereas the scar formation in control animals was less pronounced, and in some cases was accompanied by cystic transformation. Transplantation of MSCs has a positive effect on neurological and morphofunctional recovery of the brain in experimental animal models of cerebral venous circulation disorders

Remote and local monitoring of dissolved and suspended fluorescent organic matter off the Svalbard

Distribution maps of CDOM and algal pigments, both in superficial and deep waters, have been obtained operating a portable dual laser spectrofluorometer and a lidar fluorosensor equipments for the first time during two polish AREX oceanographic campaigns in 2006 and 2007 summertime in the Svalbard area. The different hydrological regimes strongly affected the biological factors in the waters around the Svalbard Islands as monitored during the campaigns with strong regional differentiations between the two years. The occurrence of large phytoplanktonic blooms and patches have been observed in the western area of the Spitsbergen Island coastline due to the nutrient release from pack ice and/or iceberg melting with values of more than 10 µg/l in both campaigns. Different CDOM fractions have been monitored with the remote and local instruments and inverse proportionality with salinity is confirmed along the water column. Phycobilin pigments, as phycoerythrin and phycocyanin accessory algal pigments, have been monitored in the northern area as well as tyrosine and tryptophan protein-like fluorescence distribution. The double filtration, performed with the dual laser spectrofluorometer, allows to retrieve the small fluorescence contribution due to NADPH and carotenoids pigments in the blue fluorescence emission. Successively, the large spectroscopic data base has been critically analyzed with a robust statistic instrument, thus identifying different marine provinces and retrieve distinctive CDOM fractions

Temporal and structural genetic variation in reindeer (Rangifer tarandus) associated with the pastoral transition in Northwestern Siberia

Funding Information NordForsk. Grant Number: 76915 ERC Advanced Grant. Grant Numbers: 295458, ESRC ES/, M011054/1 JPI HUMANOR ERC Starting GrantPeer reviewedPublisher PD

Origin and Post-Glacial Dispersal of Mitochondrial DNA Haplogroups C and D in Northern Asia

More than a half of the northern Asian pool of human mitochondrial DNA (mtDNA) is fragmented into a number of subclades of haplogroups C and D, two of the most frequent haplogroups throughout northern, eastern, central Asia and America. While there has been considerable recent progress in studying mitochondrial variation in eastern Asia and America at the complete genome resolution, little comparable data is available for regions such as southern Siberia – the area where most of northern Asian haplogroups, including C and D, likely diversified. This gap in our knowledge causes a serious barrier for progress in understanding the demographic pre-history of northern Eurasia in general. Here we describe the phylogeography of haplogroups C and D in the populations of northern and eastern Asia. We have analyzed 770 samples from haplogroups C and D (174 and 596, respectively) at high resolution, including 182 novel complete mtDNA sequences representing haplogroups C and D (83 and 99, respectively). The present-day variation of haplogroups C and D suggests that these mtDNA clades expanded before the Last Glacial Maximum (LGM), with their oldest lineages being present in the eastern Asia. Unlike in eastern Asia, most of the northern Asian variants of haplogroups C and D began the expansion after the LGM, thus pointing to post-glacial re-colonization of northern Asia. Our results show that both haplogroups were involved in migrations, from eastern Asia and southern Siberia to eastern and northeastern Europe, likely during the middle Holocene