Spatial variation in the MRE throughout the Scottish Post-Roman to late Medieval period: North Sea values (500-1350 BP)

The marine radiocarbon reservoir effect (MRE) occurs as a spatially and temporally dependent variable owing to localized changes in oceanic water composition. This study investigates ΔR values (deviations from the global average MRE whose ΔR = 0) during the period 500–1350 BP for the east coast of Scotland, where a complex estuarine system exists that drains into the semi-enclosed North Sea basin. Due to the availability of suitable archaeological samples, the data set has a distinct Medieval focus that spans the area from Aberdeen in the north to East Lothian in the south. Many of the ΔR values are not significantly different from 0 (the global average), but there are occasional excursions to negative values (max –172 ± 20) indicating the presence of younger water. These values show greater variability compared to other published data for this general region, suggesting that considerable care must be taken when dating marine derived samples from archaeological sites on the east coast of Scotland

Numerical investigation of gapped edge states in fractional quantum Hall-superconductor heterostructures

Fractional quantum Hall-superconductor heterostructures may provide a platform towards non-abelian topological modes beyond Majoranas. However their quantitative theoretical study remains extremely challenging. We propose and implement a numerical setup for studying edge states of fractional quantum Hall droplets with a superconducting instability. The fully gapped edges carry a topological degree of freedom that can encode quantum information protected against local perturbations. We simulate such a system numerically using exact diagonalization by restricting the calculation to the quasihole-subspace of a (time-reversal symmetric) bilayer fractional quantum Hall system of Laughlin $\nu=1/3$ states. We show that the edge ground states are permuted by spin-dependent flux insertion and demonstrate their fractional $6\pi$ Josephson effect, evidencing their topological nature and the Cooper pairing of fractionalized quasiparticles.Comment: 12 pages, 9 figure

Fragmentation of Nuclei at Intermediate and High Energies in Modified Cascade Model

The process of nuclear multifragmentation has been implemented, together with evaporation and fission channels of the disintegration of excited remnants in nucleus-nucleus collisions using percolation theory and the intranuclear cascade model. Colliding nuclei are treated as face--centered--cubic lattices with nucleons occupying the nodes of the lattice. The site--bond percolation model is used. The code can be applied for calculation of the fragmentation of nuclei in spallation and multifragmentation reactions.Comment: 19 pages, 10 figure

Structure of human transthyretin complexed with bromophenols: a new mode of binding

The binding of two organohalogen substances, pentabromophenol (PBP) and 2,4,6-tribromophenol (TBP), to human transthyretin (TTR), a thyroid hormone transport protein, has been studied by in vitro competitive binding assays and by X-ray crystallography. Both compounds bind to TTR with high affinity, in competition with the natural ligand thyroxine (

Ceramic regenerator systems development program

Ceramic regenerator cores are considered that can be used in passenger car gas turbine engines, Stirling engines, and industrial/truck gas turbine engines. Improved materials and design concepts aimed at reducing or eliminating chemical attack were placed on durability test in Ford 707 industrial gas turbine engines. The results of 19,600 hours of turbine engine durability testing are described. Two materials, aluminum silicate and magnesium aluminum silicate, continue to show promise toward achieving the durability objectives of this program. A regenerator core made from aluminum silicate showed minimal evidence of chemical attack damage after 6935 hours of engine test at 800 C and another showed little distress after 3510 hours at 982 C. Results obtained in ceramic material screening tests, aerothermodynamic performance tests, stress analysis, cost studies, and material specifications are also included

Evaluation of advanced regenerator systems

The major considerations are discussed which will affect the selection of a ceramic regenerative heat exchanger for an improved 100 HP automotive gas turbine engine. The regenerator considered for this application is about 36cm in diameter. Regenerator comparisons are made on the basis of material, method of fabrication, cost, and performance. A regenerator inlet temperature of 1000 C is assumed for performance comparisons, and laboratory test results are discussed for material comparisons at 1100 and 1200 C. Engine test results using the Ford 707 industrial gas turbine engine are also discussed

Tracking Data Acquisition System (TDAS) for the 1990's. Volume 6: TDAS navigation system architecture

One-way range and Doppler methods for providing user orbit and time determination are examined. Forward link beacon tracking, with on-board processing of independent navigation signals broadcast continuously by TDAS spacecraft; forward link scheduled tracking; with on-board processing of navigation data received during scheduled TDAS forward link service intervals; and return link scheduled tracking; with ground-based processing of user generated navigation data during scheduled TDAS return link service intervals are discussed. A system level definition and requirements assessment for each alternative, an evaluation of potential navigation performance and comparison with TDAS mission model requirements is included. TDAS satellite tracking is also addressed for two alternatives: BRTS and VLBI tracking

Immune compromise in HIV-1/HTLV-1 coinfection with paradoxical resolution of CD4 lymphocytosis during antiretroviral therapy: a case report

Human immunodeficiency virus type-1 (HIV-1) and human T lymphotropic virus type-1 (HTLV-1) infections have complex effects on adaptive immunity, with specific tropism for, but contrasting effects on, CD4 T lymphocytes: depletion with HIV-1, proliferation with HTLV-1. Impaired T lymphocyte function occurs early in HIV-1 infection but opportunistic infections (OIs) rarely occur in the absence of CD4 lymphopenia. In the unusual case where a HIV-1 infected individual with a high CD4 count presents with recurrent OIs, a clinician is faced with the possibility of a second underlying comorbidity. We present a case of pseudo-adult T cell leukemia/lymphoma (ATLL) in HIV-1/HTLV-1 coinfection where the individual fulfilled Shimoyama criteria for chronic ATLL and had pulmonary Mycobacterium kansasii, despite a high CD4 lymphocyte count. However, there was no evidence of clonal T-cell proliferation by T-cell receptor gene rearrangement studies nor of monoclonal HTLV-1 integration by high-throughput sequencing. Mutually beneficial interplay between HIV-1 and HTLV-1, maintaining high level HIV-1 and HTLV-1 viremia and proliferation of poorly functional CD4 cells despite chronicity of infection is a postulated mechanism. Despite good microbiological response to antimycobacterial therapy, the patient remained systemically unwell with refractory anemia. Subsequent initiation of combined antiretroviral therapy led to paradoxical resolution of CD4 T lymphocytosis as well as HIV-1 viral suppression and decreased HTLV-1 proviral load. This is proposed to be the result of attenuation of immune activation post-HIV virological control. This case illustrates the importance of screening for HTLV-1 in HIV-1 patients with appropriate clinical presentation and epidemiological risk factors and explores mechanisms for the complex interactions on HIV-1/HTLV-1 adaptive immunity

Conformal thin-sandwich puncture initial data for boosted black holes

We apply the puncture approach to conformal thin-sandwich black-hole initial data. We solve numerically the conformal thin-sandwich puncture (CTSP) equations for a single black hole with non-zero linear momentum. We show that conformally flat solutions for a boosted black hole have the same maximum gravitational radiation content as the corresponding Bowen-York solution in the conformal transverse-traceless decomposition. We find that the physical properties of these data are independent of the free slicing parameter.Comment: 12 pages, 11 figure