160 research outputs found

    Analysis of the Folders of the Freshman Agricultural Students Taking First Semester Freshman English supplemented by a Classified Bibliography of Periodical Literature for the Teaching of English

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    This study attempts to combine, in one book, some hints and suggestions for good writing, based upon sound principles and written primarily for the Prairie View student, with a varied collection of errors taken from compositions, letters, and other papers in the folders of thirty-five Freshman Agricultural students taking Freshman English. Supplementary material has been added in the form of a classified bibliography of periodical literature for the teaching of English. In Part I a classification of errors is given. Part II consists of a test composed of common errors made by students in the class. Letter-writing is given special notice in Part III, and a classified bibliography is given in Part IV. The course outline will be found in the Appendix. The writer has endeavored to give to each part the proportionate space and the kind which will perhaps gain the attention of the average student. No thought is held by the author of these pages that new material is being added to what has previously been written but she is convinced that many students coming to the college have had little preparation, and that the usual presentation of rhetoric and composition leaves many of them struggling with strange material. It is not, however, the purpose of this treatise to give instruction in English Grammar. It is hoped and expected that those who take up this treatise for guidance will have received a good groundwork in grammar

    Attachment and couple sexual functioning

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    Within the last several years, there has been a surge in the publications that focus on attachment within the couple relationships, including how it pertains to infidelity treatment. Despite the interest in couple relationships and attachment, however, a limited amount of literature focuses on how varying styles of attachment manifest in a couple\u27s level of sexual functioning. This study is a response to the need to explore the literature and related gaps in literature

    Lower Limb Muscle Activation in Young Adults Walking in Water and on Land

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    Previous research has shown that exercise interventions requiring increased activation of the tibialis anterior (TA), the primary ankle dorsiflexor, can improve walking performance in individuals with foot drop. Correspondingly, heightened drag forces experienced during walking performed in water may augment TA activation during the swing phase of gait, potentially leading to improved walking gait on land. Therefore, this study aimed to compare surface electromyographic (sEMG) activation in the TA and medial gastrocnemius (GM) during gait performed in water versus on land. Thirty-eight healthy, recreationally active young adults, comprising 18 females and 20 males, participated in the study. Each participant completed 2 min walking trials under five conditions: land 2.5 mph, land 3.5 mph, water 2.5 mph, water 3.5 mph, and water 3.5 mph with added jet resistance. Stride kinematics were collected using 2-dimensional underwater motion capture. TA and GM, muscle activation magnitudes, were quantified using sEMG root-mean-square (RMS) amplitudes for both the swing and stance phases of walking. Additionally, TA and GM co-activation (Co-A) indices were estimated. Two-way within-subjects repeated measures analyses of variance were used to evaluate the main effects of and interactions between the environment and walking speed. Additionally, paired sample t-tests were conducted as a secondary analysis to investigate differences between walking in water at 3.5 mph with and without added jet resistance. Main effects and interactions were observed across various stride kinematics and sEMG measures. Notably, TA sEMG RMS during the swing phase of walking gait performed at 2.5 mph was 15% greater in water than on land (p \u3c 0.001). This effect increased when walking gait was performed at 3.5 mph (94%; p \u3c 0.001) and when jet resistance was added to the 3.5 mph condition (52%; p \u3c 0.001). Furthermore, TA Co-A was increased during the stance phase of gait in water compared to on land (p \u3c 0.001), while GM Co-A was reduced during the swing phase (p \u3c 0.001). The findings of this study offer compelling evidence supporting the efficacy of aquatic treadmill walking as a potential treatment for individuals suffering from foot drop. However, further research is needed to evaluate whether a causal relationship exists between heightened TA activation observed during aquatic treadmill walking and improvements in voluntary dorsiflexion during gait

    The gene product Murr1 restricts HIV-1 replication in resting CD4(+) lymphocytes

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    Although human immunodeficiency virus-1 (HIV-1) infects quiescent and proliferating CD4(+) lymphocytes, the virus replicates poorly in resting T cells(1-6). Factors that block viral replication in these cells might help to prolong the asymptomatic phase of HIV infection(7); however, the molecular mechanisms that control this process are not fully understood. Here we show that Murr1, a gene product known previously for its involvement in copper regulation(8,9), inhibits HIV-1 growth in unstimulated CD4(+) T cells. This inhibition was mediated in part through its ability to inhibit basal and cytokine-stimulated nuclear factor (NF)-kappaB activity. Knockdown of Murr1 increased NF-kappaB activity and decreased IkappaB-alpha concentrations by facilitating phospho-IkappaB-alpha degradation by the proteasome. Murr1 was detected in CD4(+) T cells, and RNA-mediated interference of Murr1 in primary resting CD4(+) lymphocytes increased HIV-1 replication. Through its effects on the proteasome, Murr1 acts as a genetic restriction factor that inhibits HIV-1 replication in lymphocytes, which could contribute to the regulation of asymptomatic HIV infection and the progression of AIDS.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/62709/1/nature02171.pd

    How Methods for Navigating Uncertainty Connect Science and Policy at the Water-Energy-Food Nexus

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    As the water-energy-food (WEF) nexus becomes an increasingly common framework for bridging science and policy, there is a growing need to unpack and make explicit many of the methods and assumptions being used to operationalize the nexus. In this paper, we focus on two common approaches to nexus research, quantitative modeling and futures thinking, and the ways that each set of methodological tools address uncertainty. We first review the underlying assumptions of each approach with a focus on sources of and ability to measure uncertainty, and potential complementarities. Quantitative modeling takes a probabilistic approach to predicting the likelihood of a specific outcome or future state based on estimates of current system dynamics. In contrast, futures thinking approaches, such as scenario processes, explore novel changes that cannot be fully predicted or even anticipated based on current understandings of the nexus. We then examine a set of applied nexus projects that bridge science and policy-making contexts to better understand practitioner experiences with different methodological tools and how they are utilized to navigate uncertainty. We explore one nexus case study, LIVES Cambodia, in-depth, to better understand the opportunities and challenges associated with participatory modeling and stakeholder engagement with uncertainty in a policy-making context. Across the cases, practitioners identify the complementarity between modeling and futures thinking approaches, and those projects that integrated both into the planning process experienced benefits from having multiple angles on uncertainty within the nexus. In particular, stakeholder engagement provided critical opportunities to address some types of uncertainties (e.g., data gaps) through the use of local knowledge. Explicit discussions of model uncertainty and use of scenario processes also enabled stakeholders to deepen their understandings of uncertainties and envision policy pathways that would be robust to uncertainty. In many senses, models became boundary objects that encouraged critical thinking and questioning of assumptions across diverse stakeholders. And, for some nexus projects, confronting uncertainty in explicit and transparent ways build capacity for policy flexibility and adaptiveness. We conclude with a discussion of when and how these benefits can be fully realized through the strategic use of appropriate approaches to characterizing and navigating nexus uncertainty

    Ten Considerations for Research Funders Seeking to Enhance Knowledge Exchange and the Impact of Marine Science on Policy and Practice

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    Research funders can play an important role in supporting the integration of marine science into policy and practice to enable evidence-informed decision-making. However, to date, there is a paucity of guidance available to help research funders understand the specific actions they can take to support knowledge exchange among the researchers that they fund and relevant stakeholders, particularly within marine contexts. This Brief Research Report aims to begin to fill this gap through an in-depth case study of the Lenfest Ocean Program (LOP). Specifically, through qualitative interviews with 32 participants across eight LOP funded research projects (i.e., case studies) we sought to: (i) understand the types of impacts that have resulted from the LOP funded research, (ii) determine which activities undertaken by the LOP enabled funded research projects to achieve these impacts, and (iii) synthesize findings to articulate the core lessons that have emerged from our examination of these research projects. Results show that the concept of “research impact” is complex and can be interpreted in a number of ways including: (i) raising awareness of research among end-users, (ii) development and expansion of social networks, (iii) the provision of information to decision-makers, (iv) the development of decision-support tools, and (v) a direct contribution to policy change. We highlight the ways by which the LOP has supported the attainment of these impacts, as well as 10 general considerations that research funders should consider when seeking to enhance the impact of the research that they fund on marine policy and practice.Funding for this research was provided by the Pew Charitable Trusts

    Embryo movement is more frequent in avian brood parasites than birds with parental reproductive strategies.

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    Funder: Tanzanian Commission for Science and TechnologyFunder: Tanzania Wildlife Research InstituteFunder: NERCFunder: National Science FoundationFunder: Ministry of EducationFunder: German Academic Exchange ServiceFunder: University of Cape TownFunder: Max-Planck-GesellschaftMovement of the embryo is essential for musculoskeletal development in vertebrates, yet little is known about whether, and why, species vary. Avian brood parasites exhibit feats of strength in early life as adaptations to exploit the hosts that rear them. We hypothesized that an increase in embryonic movement could allow brood parasites to develop the required musculature for these demands. We measured embryo movement across incubation for multiple brood-parasitic and non-parasitic bird species. Using a phylogenetically controlled analysis, we found that brood parasites exhibited significantly increased muscular movement during incubation compared to non-parasites. This suggests that increased embryo movement may facilitate the development of the stronger musculoskeletal system required for the demanding tasks undertaken by young brood parasites

    Understanding the Impacts of Research Synthesis

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    Research synthesis is the integration of existing knowledge and research findings pertinent to an issue. The aim of synthesis is to increase the generality and applicability of those findings and to develop new knowledge through the process of integration. Synthesis is promoted as an approach that deals with the challenge of öinformation overload’, delivering products that further our understanding of problems and distil relevant evidence for decision-making. However, despite the increasing prominence of synthesis efforts in the science and policy landscape, we know very little about the impacts these initiatives have on research, policy and practice and the assumptions underpinning how they will lead to change. This paper presents a framework for considering the conceptual, strategic, instrumental and network-based impacts of research synthesis on policy. This framework provides insight into the range of underlying assumptions and impacts on policy and practice from 10 case studies of research synthesis related to contemporary sustainability challenges. Findings suggest that research synthesis is having diverse impacts on research, policy and practice including creating a new understanding of problems, establishing new networks, and contributing to changes in policy and practice. These impacts emerged across a range of contexts, synthesis methods, assumptions and operating models. This suggests that there is no single öcorrect way’ to design research synthesis for impact, but rather a need to tailor the approach for the context of intended use
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