Vertical distribution and diurnal fluctuations of zooplankton in the Gotland Deep, June 1969, a Baltic Year study : preliminary report

The study describes the results of zooplankton sampling during a short period of the International Baltic Year at station F 81 (BY 15 A) in the Gotland Deep. An analysis has been made of the abundance at different depths of the commonest species belonging to the groups: Copepoda, Cladocera, Rotifera, and "others". A clear diurnal pattern could be distinguished mainly for the copepods, which were strongly dominant. Their vertical distribution showed both interspecific differences and intraspecific differences between developmental stages. The cladocerans were still very rare at that time of the summer, their numbers being too low for any definite conclusions

Intermittency of Height Fluctuations and Velocity Increment of The Kardar-Parisi-Zhang and Burgers Equations with infinitesimal surface tension and Viscosity in 1+1 Dimensions

The Kardar-Parisi-Zhang (KPZ) equation with infinitesimal surface tension, dynamically develops sharply connected valley structures within which the height derivative is not continuous. We discuss the intermittency issue in the problem of stationary state forced KPZ equation in 1+1--dimensions. It is proved that the moments of height increments $C_a =$ behave as $|x_1 -x_2|^{\xi_a}$ with $\xi_a = a$ for length scales $|x_1-x_2| << \sigma$. The length scale $\sigma$ is the characteristic length of the forcing term. We have checked the analytical results by direct numerical simulation.Comment: 13 pages, 9 figure

The decline of macrofauna in the deeper parts of the Baltic proper and the Gulf of Finland

An attempt is made to describe the large-scale changes in the benthic soft bottom macrofauna in the deep parts of the Bornholm Basin, the Gulf of Gdansk, the Central Basin and the Gulf of Finland, from the beginning of Baltic zoobenthos research to the present day. The authors also try to correlate these changes with fluctuations in the oxygen content and salinity in near-bottom water layers. The paper surveys the literature and presents recent, earlier unpublished results. During the later part of last century and the first decades of the twentieth century no area of the Baltic Sea seems to have been total ly devoid of macrofauna. Unfortunately there are considerable gaps in our knowledge of the time before the middle of this century. The most striking decline has taken place, generally speaking, after the exceptionally great inflow in 1951-1952, and the subsequent prolonged stagnation. The first records of "dead" bottoms in the Bornholm Basin are from 1948, when no macrofauna was recorded below 80 m. Records from 1954 show that the deepest parts of the Eastern Gotland Basin and the deep area between Öland and Gotland were devoid of macrofauna at that time, but that the deep areas of the northernmost Baltic proper and the Gulf of Finland were still populated. The change continued, and during the 1960s the communities dominated by lamellibranchs in the Bornholm and Gdansk Deeps disappeared, and were subsequently replaced by polychaete cummunities. These have been wiped out during periods of bad oxygen conditions, but quickly re-established when conditions had improved. The lamellibranch community has not been restored. In the Northern Central Basin and the Gulf of Finland the depopulation of the deep bottoms probably began later, in the late 50s. In the 70s practically no macrofauna has been recorded below the permanent halocline in the Central Basin (except the southernmost parts of it) and the Gulf of Finland. During the 60s and 70s the area with periodically unfavourable oxygen conditions has covered about 100000 km2, which is c. 25 % of the total area of the Baltic Sea

Matrix generalizations of some dynamic field theories

We introduce matrix generalizations of the Navier--Stokes (NS) equation for fluid flow, and the Kardar--Parisi--Zhang (KPZ) equation for interface growth. The underlying field, velocity for the NS equation, or the height in the case of KPZ, is promoted to a matrix that transforms as the adjoint representation of $SU(N)$. Perturbative expansions simplify in the $N\to\infty$ limit, dominated by planar graphs. We provide the results of a one--loop analysis, but have not succeeded in finding the full solution of the theory in this limit.Comment: 9 pages, Hard copy figures available from: [email protected]

A Non-Associative Deformation of Yang-Mills Gauge Theory

An ansatz is presented for a possible non-associative deformation of the standard Yang-Mills type gauge theories. An explicit algebraic structure for the deformed gauge symmetry is put forward and the resulting gauge theory developed. The non-associative deformation is constructed in such a way that an apparently associative Lie algebraic structure is retained modulo a closure problem for the generators. It is this failure to close which leads to new physics in the model as manifest in the gauge field kinetic term in the resulting Lagrangian. A possible connection between this model and quantum group gauge theories is also investigated.Comment: 18 pages, RevTeX, also uses aps.st

In vivo microdialysis to determine subcutaneous interstitial fluid penetration and pharmacokinetics of fluconazole in intensive care unit patients with sepsis

The objective of the study was to describe the subcutaneous interstitial fluid (ISF) pharmacokinetics of fluconazole in critically ill patients with sepsis. This prospective observational study was conducted at two tertiary intensive care units in Australia. Serial fluconazole concentrations were measured over 24 h in plasma and subcutaneous ISF using microdialysis. The concentrations in plasma and microdialysate were measured using a validated high-performance liquid chromatography system with electrospray mass spectrometer detector method. Noncompartmental pharmacokinetic analysis was performed. Twelve critically ill patients with sepsis were enrolled. The mean in vivo fluconazole recovery rates +/- standard deviation (SD) for microdialysis were 51.4% +/- 16.1% with a mean (+/- SD) fluconazole ISF penetration ratio of 0.52 +/- 0.30 (coefficient of variation, 58%). The median free plasma area under the concentration-time curve from 0 to 24 h (AUC(0-24)) was significantly higher than the median ISF AUC(0-24) (340.4 versus 141.1 mg . h/liter; P = 0.004). There was no statistical difference in median fluconazole ISF penetration between patients receiving and not receiving vasopressors (median, 0.28 versus 0.78; P = 0.106). Both minimum and the maximum concentrations of drug in serum (C-max and C-min) showed a significant correlation with the fluconazole plasma exposure (Cmax, R-2 = 0.86, P < 0.0001; Cmin, R-2 = 0.75, P < 0.001). Our data suggest that fluconazole was distributed variably, but incompletely, from plasma into subcutaneous interstitial fluid in this cohort of critically ill patients with sepsis. Given the variability of fluconazole interstitial fluid exposures and lack of clinically identifiable factors by which to recognize patients with reduced distribution/exposure, we suggest higher than standard doses to ensure that drug exposure is adequate at the site of infection

Universal Ratios in the 2-D Tricritical Ising Model

We consider the universality class of the two-dimensional Tricritical Ising Model. The scaling form of the free-energy naturally leads to the definition of universal ratios of critical amplitudes which may have experimental relevance. We compute these universal ratios by a combined use of results coming from Perturbed Conformal Field Theory, Integrable Quantum Field Theory and numerical methods.Comment: 4 pages, LATEX fil

Utilización del túnel de viento como herramienta para el análisis de tanques de petróleo en la Norpatagonia

En este trabajo se presentan una serie de ensayos realizados en túnel de viento, sobre distintos modelos de tanques correspondientes a dimensiones que se emplean con frecuencia en la industria del petróleo en las provincias de Río Negro y Neuquén, unos para analizar los colapsos ocurridos en tanques aislados y en fase de construcción, otros sobre tanques agrupados en baterías para cuantificar las sobrecargas que se generan por interferencia entre los mismos. Los modelos ensayados correspondientes a tanques en etapa constructiva tienen la condición de abierto en la parte superior, ya que el techo aun no estaba montado, mientras que los modelos para evaluar el efecto de grupo tienen techo cónico, considerándose diferentes separaciones entre ambos y direcciones de incidencia de viento variables. Los ensayos arrojaron patrones de flujos que produjeron cargas adicionales que no se tienen en cuenta en las actuales normas de diseño. Los coeficientes de presión medidos permiten realizar modelaciones numéricas para analizar la estabilidad de los tanques.Laboratorio de Capa Límite y Fluidodinámica AmbientalGrupo Fluidodinámica Computaciona

Effect of obesity on the population pharmacokinetics of meropenem in critically ill patients

Severe pathophysiological changes in critical illness can lead to dramatically altered antimicrobial pharmacokinetics (PK). The additional effect of obesity on PK potentially increases the challenge for effective dosing. The aim of this prospective study was to describe the population PK of meropenem for a cohort of critically ill patients, including obese and morbidly obese patients. Critically ill patients prescribed meropenem were recruited into the following three body mass index (BMI) groups: nonobese (18.5 to 29.9 kg/m(2)), obese (30.0 to 39.9 kg/m(2)), and morbidly obese (>= 40 kg/m(2)). Serial plasma samples were taken, and meropenem concentrations were determined using a validated chromatographic method. Population PK analysis and Monte Carlo dosing simulations were undertaken with Pmetrics. Nineteen critically ill patients with different BMI categories were enrolled. The patients' mean +/- standard deviation (SD) age, weight, and BMI were 49 +/- 15.9 years, 95 +/- 22.0 kg, and 33 +/- 7.0 kg/m(2), respectively. A two-compartment model described the data adequately. The mean +/- SD parameter estimates for the final covariate model were as follows: clearance (CL), 15.5 +/- 6.0 liters/h; volume of distribution in the central compartment (V-1), 11.7 +/- 5.8 liters; intercompartmental clearance from the central compartment to the peripheral compartment, 25.6 +/- 35.1 liters h(-1); and intercompartmental clearance from the peripheral compartment to the central compartment, 8.32 +/- 12.24 liters h(-1). Higher creatinine clearance (CLCR) was associated with a lower probability of target attainment, with BMI having little effect. Although obesity was found to be associated with an increased V-1, dose adjustment based on CLCR appears to be more important than patient BMI