18 research outputs found
Arterial stiffness and stroke in sickle cell disease
BACKGROUND AND PURPOSE: Large vessels are also affected in sickle cell disease. The aim of this study was to assess several parameters in adult patients with sickle cell disease compared with control subjects and in patients with sickle cell disease with stroke. METHODS: Carotid arterial stiffness, intima-media thickness, and transcranial Doppler ultrasonography were measured. RESULTS: Arterial stiffness and transcranial Doppler velocity were significantly increased in 49 patients with sickle cell disease compared with 47 control subjects (P<0.05) and especially in patients with stroke (P<0.05). CONCLUSIONS: These data suggest that transcranial Doppler and arterial stiffness might be associated to stroke in adult patients with sickle cell disease
Hodgkin lymphoma in a sickle cell anaemia child treated with hydroxyurea
International audienc
L’hémolyse post-transfusionnelle retardée : à propos de 3 patients drépanocytaires
International audienc
Hétérogénéité génotypique du déficit en G6PD à l’Ouest de l’Afrique Sub-saharienne
abstract: Hématologie 2000; 6(HS):45info:eu-repo/semantics/nonPublishe
Hb Mont Saint Aignan [beta 128(H6)Ala -> Pro]: A new unstable variant leading to chronic microcytic anemia
Hb Mont Saint-Aignan [beta 128(H6)Ala –> Pro] is a mildly unstable
variant, associated with hemolytic anemia, marked microcytosis and
increased alp biosynthetic ratio (1.55 versus 1.1 +/-0.1 in the
control). The abnormal chain was isolated by selective precipitation
with isopropanol and the structural modification determined by protein
chemistry methods (reversed phase high performance liquid chromatography
and mass spectrometry). Possible mechanisms underlying the beta
(+)-thalassemia-like expression of this variant are discussed
L’hémolyse post-transfusionnelle retardée : à propos de 3 patients drépanocytaires
International audienc
HEREDITARY XEROCYTOSIS: CLINICAL AND BIOLOGICAL PRESENTATION AT DIAGNOSIS IN A RETROSPECTIVE SERIES OF 103 PATIENTS
22nd Congress of the European-Hematology-Association, Madrid, SPAIN, JUN 22-25, 2017International audienc
HEREDITARY XEROCYTOSIS: CLINICAL AND BIOLOGICAL PRESENTATION AT DIAGNOSIS IN A RETROSPECTIVE SERIES OF 103 PATIENTS
22nd Congress of the European-Hematology-Association, Madrid, SPAIN, JUN 22-25, 2017International audienc