97 research outputs found
Evaluation of Cellular Fibronectin Plasma Levels as a Useful Staging Tool in Different Stages of Transitional Cell Carcinoma of the Bladder and Renal Cell Carcinoma
Reliable markers for both renal cell carcinoma (RCC) and transitional cell carcinoma of the bladder (TCC) are lacking
Determination of the Michel Parameters rho, xi, and delta in tau-Lepton Decays with tau --> rho nu Tags
Using the ARGUS detector at the storage ring DORIS II, we have
measured the Michel parameters , , and for
decays in -pair events produced at
center of mass energies in the region of the resonances. Using
as spin analyzing tags, we find , , , , and . In addition, we report
the combined ARGUS results on , , and using this work
und previous measurements.Comment: 10 pages, well formatted postscript can be found at
http://pktw06.phy.tu-dresden.de/iktp/pub/desy97-194.p
A Search for the Electric Dipole Moment of the Tau-Lepton
Using the ARGUS detector at the e+e- storage ring DORIS II, we have searched
for the real and imaginary part of the electric dipole formfactor d_tau of the
tau lepton in the production of tau pairs at q^2=100 GeV^2. This is the first
direct measurement of this CP violating formfactor. We applied the method of
optimised observables which takes into account all available information on the
observed tau decay products. No evidence for CP violation was found, and we
derive the following results: Re(d_tau)=(1.6+-.9)*10^(-16) ecm and
Im(d_tau)=(-0.2+-0.8)*10^(-16) ecm, where statistical and systematic errors
have been combined.Comment: 8 pages, 5 figures (10 subfigures
Unstable neurons underlie a stable learned behavior
Motor skills can be maintained for decades, but the biological basis of this memory persistence remains largely unknown. The zebra finch, for example, sings a highly stereotyped song that is stable for years, but it is not known whether the precise neural patterns underlying song are stable or shift from day to day. Here we demonstrate that the population of projection neurons coding for song in the premotor nucleus, HVC, change from day to day. The most dramatic shifts occur over intervals of sleep. In contrast to the transient participation of excitatory neurons, ensemble measurements dominated by inhibition persist unchanged even after damage to downstream motor nerves. These observations offer a principle of motor stability: spatiotemporal patterns of inhibition can maintain a stable scaffold for motor dynamics while the population of principal neurons that directly drive behavior shift from one day to the next
General anesthesia globally synchronizes activity selectively in layer 5 cortical pyramidal neurons
General anesthetics induce loss of consciousness, a global change in behavior. However, a corresponding global change in activity in the context of defined cortical cell types has not been identified. Here, we show that spontaneous activity of mouse layer 5 pyramidal neurons, but of no other cortical cell type, becomes consistently synchronized invivo by different general anesthetics. This heightened neuronal synchrony is aperiodic, present across large distances, and absent in cortical neurons presynaptic to layer 5 pyramidal neurons. During the transition to and from anesthesia, changes in synchrony in layer 5 coincide with the loss and recovery of consciousness. Activity within both apical and basal dendrites is synchronous, but only basal dendrites' activity is temporally locked to somatic activity. Given that layer 5 is a major cortical output, our results suggest that brain-wide synchrony in layer 5 pyramidal neurons may contribute to the loss of consciousness during general anesthesia. Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved
On the Effect of Monomer Chemistry on Growth Mechanisms of Nonfouling PEG-like Plasma Polymers
It has been shown that both ions and neutral species
may contribute
to plasma polymer growth. However, the relative contribution from
these mechanisms remains unclear. We present data elucidating the
importance of considering monomer structure with respect to which
the growth mechanism dominates for nonfouling PEG-like plasma polymers.
The deposition rate for saturated monomers is directly linked with
ion flux to the substrate. For unsaturated monomers, the neutral flux
also plays a role, particularly at low power. Increased fragmentation
of the monomer at high power reduces the ability of unsaturated monomers
to grow via neutral grafting. Chemical characterization by X-ray photoelectron
spectroscopy (XPS) and time-of-flight secondary ion mass spectrometry
(ToF-SIMS) confirm the role that plasma phase fragmentation plays
in determining the deposition rate and surface chemistry of the deposited
film. The simple experimental method used here may also be used to
determine which mechanisms dominate plasma deposition for other monomers.
This knowledge may enable significant improvement in future reactor
design and process control
- …