Characterization of wavelength interleaving in radio-over-fiber systems employing WDM/SCM

A radio-over-fiber (RoF) distribution system incorporating both sub-carrier multiplexing and wavelength division multiplexing (WDM) technologies is presented. This signal is directly modulated onto three high-speed lasers. Bragg filters are employed at the receiver base station in order to both demultiplex the required optical channel, and ensure that the detected signal is single side band (in order to overcome dispersion limitations of the link). System spectral efficiency is optimised by wavelength interleaving. The channel spacing between the WDM channels is varied and the system performance for different values of channel spacing and spectral efficiencies is investigated. The results show that wavelength interleaving is a reliable technique that could be used to increase the spectral efficiency of RoF systems

Overcoming laser diode nonlinearity issues in multi-channel radio-over-fiber systems

The authors demonstrate how external light injection into a directly modulated laser diode may be used to enhance the performance of a multi-channel radio-over-fiber system operating at a frequency of 6 GHz. Performance improvements of up to 2 dB were achieved by linearisation of the lasers-modulation response. To verify the experimental work a simulation of the complete system was carried out using Matlab. Good correlation was observed between experimental and simulated results

Cost efficient narrow linewidth laser transmitter for coherent detection

Authors present a cost efficient narrow linewidth laser transmitter for future coherent detection systems. The spectral purity of the laser allows the phase modulation of data signals at bit rates as low as 155 Mb/s

Optimized pulse source based on a gain-switched laser diode in conjuction with a non-linearly chirped grating for 40 Gbit/s systems

A technique based on the design of an optimized source of pico-second optical pulses, which exhibits excellent temporal and spectral purity, is presented. The procedure entails an initial complete intensity and chirp characterization of pulses, from an externally injected-gain switched laser (EI-GSL), using the technique of frequency resolved optical gating (FROG). This characterization yields the parameters that are required for the design of a non-linearly chirped fibre Bragg grating (NC FBG) with a chirp profile that is opposite to that measured across the pulse. By employing the tailor made NC FBG after the gain-switched laser, direct compression of the gain-switched pulses is achieved, to obtain pedestal-free, near transform-limited, 7 ps pulses. The system viability, characterized by simulations, portrays a 6 dB difference in performance between a pulse source with insufficient TPSR and one that exhibits adequate TPSR &(ge; 30 dB)

Performance Issues Associated With WDM Optical Systems Using Self-Seeded Gain Switched Pulse Sources Due to Mode Partition Noise Effects

Abstract-Bit-error-rate measurements have been carried out on a four-channel wavelength division multiplexed setup using tunable self-seeded gain-switched pulse sources. These measurements demonstrate the degradation in overall system performance, due to mode partition noise, as the sidemode suppression ratio of the self-seeded gain-switched optical pulse sources is reduced. The results also show that the constraints on the minimum sidemode suppression ratio required increase with the number of channels in the system. Index Terms-Optical fiber communications, optical pulse generation, mode partition noise, semiconductor laser, wavelength-division multiplexing

Inflammatory and Immunological parameters in adults with Down syndrome

<p>Abstract</p> <p>Background</p> <p>The increase in life expectancy within the general population has resulted in an increasing number of elderly adults, including patients with Down syndrome (DS), with a current life expectancy of about 50 years. We evaluate the parameters of humoral and cellular immune response, the quantitative expression of the regulator of calcineurin1 gene (RCAN1) and the production of cytokines. The study group consisted of adults DS (n = 24) and a control group with intellectual disability without Down syndrome (ID) (n = 21) and living in a similar environmental background. It was evaluated serology, immunophenotyping, the quantitative gene expression of RCAN1 and the production of cytokines.</p> <p>Results</p> <p>In the DS group, the results showed an increase in NK cells, CD8, decreased CD19 (p < 0.05) and an increase spontaneous production of IFNgamma, TNFalpha and IL-10 (p < 0.05). There was not any difference in RCAN1 gene expression between the groups.</p> <p>Conclusions</p> <p>These data suggest a similar humoral response in the two groups. The immunophenotyping suggests sign of premature aging of the immune system and the cytokine production show a proinflammatory profile.</p

Stress, ageing and their influence on functional, cellular and molecular aspects of the immune system

The immune response is essential for keeping an organism healthy and for defending it from different types of pathogens. It is a complex system that consists of a large number of components performing different functions. The adequate and controlled interaction between these components is necessary for a robust and strong immune response. There are, however, many factors that interfere with the way the immune response functions. Stress and ageing now consistently appear in the literature as factors that act upon the immune system in the way that is often damaging. This review focuses on the role of stress and ageing in altering the robustness of the immune response first separately, and then simultaneously, discussing the effects that emerge from their interplay. The special focus is on the psychological stress and the impact that it has at different levels, from the whole system to the individual molecules, resulting in consequences for physical health