Disorder-induced melting of the charge order in thin films of Pr0.5Ca0.5MnO3

We have studied the magnetic-field-induced melting of the charge order in thin films of Pr0.5Ca0.5MnO3 (PCMO) films on SrTiO3 (STO) by X-ray diffraction, magnetization and transport measurement. At small thickness (25 nm) the films are under tensile strain and the low-temperature melting fields are of the order of 20 T or more, comparable to the bulk value. With increasing film thickness the strain relaxes, which leads to a strong decrease of the melting fields. For a film of 150 nm, with in-plane and out-of-plane lattice parameters closer to the bulk value, the melting field has reduced to 4 T at 50 K, with a strong increase in the hysteretic behavior and also an increasing fraction of ferromagnetic material. Strain relaxation by growth on a template of YBa2Cu3O(7-delta) or by post-annealing yields similar results with an even stronger reduction of the melting field. Apparently, strained films behave bulk-like. Relaxation leads to increasing suppression of the CO state, presumably due to atomic scale disorder produced by the relaxation process.Comment: 7 pages, 4 fig

Non-Fermi-liquid behavior in Ce(Ru1−x_{1-x}Fex_x)2_2Ge2_2: cause and effect

We present inelastic neutron scattering measurements on the intermetallic compounds Ce(Ru$_{1-x}$Fe$_x$)$_2$Ge$_2$ ($x$=0.65, 0.76 and 0.87). These compounds represent samples in a magnetically ordered phase, at a quantum critical point and in the heavy-fermion phase, respectively. We show that at high temperatures the three compositions have the identical response of a local moment system. However, at low temperatures the spin fluctuations in the critical composition are given by non-Fermi-liquid dynamics, while the spin fluctuations in the heavy fermion system show a simple exponential decay in time. In both compositions, the lifetime of the fluctuations is determined solely by the distance to the quantum critical point. We discuss the implications of these observations regarding the possible origins of non-Fermi-liquid behavior in this system.Comment: 4 figures, submitted to PR

Proximity effects in the superconductor / heavy fermion bilayer system Nb / CeCu_6

We have investigated the proximity effect between a superconductor (Nb) and a 'Heavy Fermion' system (CeCu_6) by measuring critical temperatures $T_c$ and parallel critical fields H_{c2}^{\parallel}(T) of Nb films with varying thickness deposited on 75 nm thick films of CeCu_6, and comparing the results with the behavior of similar films deposited on the normal metal Cu. For Nb on CeCu_6 we find a strong decrease of T_c with decreasing Nb thickness and a finite critical thickness of the order of 10 nm. Also, dimensional crossovers in H_{c2}^{\parallel}(T) are completely absent, in strong contrast with Nb/Cu. Analysis of the data by a proximity effect model based on the Takahashi-Tachiki theory shows that the data can be explained by taking into account both the high effective mass (or low electronic diffusion constant), {\it and} the large density of states at the Fermi energy which characterize the Heavy Fermion metal.Comment: 7 pages, 2 figure. Manuscript has been submitted to a refereed journa

Validation of an automated dispensing system for subsequent dose dispensing of different radionuclides

Background: Automated dispensing systems (ADSs) for radiopharmaceuticals have been developed to reduce the radiation exposure of personnel, to improve the accuracy of the dispensed dose and to limit the microbiological contamination. However, before implementing such systems, validation according to various applicable guidelines is necessary to ensure safety and quality. Here we present the selection, validation and implementation of the PT459R2 from manufacturer Lynax s.r.o. as a guidance protocol for validation according to GMP and GRPP guidelines. Validation included linearity accuracy and precision of the internal scintillation detector for different isotopes and microbiological validation for aseptic procedures. Results: The ADS can dispense accurate doses in the following linear range: 1000–10,000 MBq for lutetium-177, 20–74 MBq for zirconium-89, 100–1000 MBq for gallium-68 and 100–2000 MBq for fluorine-18. The maximum bias is 2.35% and the maximum coefficient of variation is 3.03% which meets the acceptance criteria of < 5%. Furthermore, the ADS does not affects the GMP class A environment in a laminar airflow cabinet and can dispense aseptically. In addition, radiation exposure is acceptable and data integrity is preserved. Conclusion: The PT459R2 ADS met all the requirements from our performance qualification and is therefore suitable for daily routine use in our center. Our approach can be used as a guidance for PQ of an ADS in a Radiopharmacy according to GMP and GRPP guidelines

Stereotype reputation with limited observability

Assessing trust and reputation is essential in multi-agent systems where agents must decide who to interact with. Assessment typically relies on the direct experience of a trustor with a trustee agent, or on information from witnesses. Where direct or witness information is unavailable, such as when agent turnover is high, stereotypes learned from common traits and behaviour can provide this information. Such traits may be only partially or subjectively observed, with witnesses not observing traits of some trustees or interpreting their observations differently. Existing stereotype-based techniques are unable to account for such partial observability and subjectivity. In this paper we propose a method for extracting information from witness observations that enables stereotypes to be applied in partially and subjectively observable dynamic environments. Specifically, we present a mechanism for learning translations between observations made by trustor and witness agents with subjective interpretations of traits. We show through simulations that such translation is necessary for reliable reputation assessments in dynamic environments with partial and subjective observability

The Haroche-Ramsey experiment as a generalized measurement

A number of atomic beam experiments, related to the Ramsey experiment and a recent experiment by Brune et al., are studied with respect to the question of complementarity. Three different procedures for obtaining information on the state of the incoming atom are compared. Positive operator-valued measures are explicitly calculated. It is demonstrated that, in principle, it is possible to choose the experimental arrangement so as to admit an interpretation as a joint non-ideal measurement yielding interference and ``which-way'' information. Comparison of the different measurements gives insight into the question of which information is provided by a (generalized) quantum mechanical measurement. For this purpose the subspaces of Hilbert-Schmidt space, spanned by the operators of the POVM, are determined for different measurement arrangements and different values of the parameters.Comment: REVTeX, 22 pages, 5 figure

Bone Marrow Stem Cell Treatment for Ischemic Heart Disease in Patients with No Option of Revascularization: A Systematic Review and Meta-Analysis

PMCID: PMC3686792This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited