Multi-Dimensional Simulations of the Accretion-Induced Collapse of White Dwarfs to Neutron Stars

We present 2.5D radiation-hydrodynamics simulations of the accretion-induced collapse (AIC) of white dwarfs, starting from 2D rotational equilibrium configurations of a 1.46-Msun and a 1.92-Msun model. Electron capture leads to the collapse to nuclear densities of these cores within a few tens of milliseconds. The shock generated at bounce moves slowly, but steadily, outwards. Within 50-100ms, the stalled shock breaks out of the white dwarf along the poles. The blast is followed by a neutrino-driven wind that develops within the white dwarf, in a cone of ~40deg opening angle about the poles, with a mass loss rate of 5-8 x 10^{-3} Msun/yr. The ejecta have an entropy on the order of 20-50 k_B/baryon, and an electron fraction distribution that is bimodal. By the end of the simulations, at >600ms after bounce, the explosion energy has reached 3-4 x 10^{49}erg and the total ejecta mass has reached a few times 0.001Msun. We estimate the asymptotic explosion energies to be lower than 10^{50}erg, significantly lower than those inferred for standard core collapse. The AIC of white dwarfs thus represents one instance where a neutrino mechanism leads undoubtedly to a successful, albeit weak, explosion. We document in detail the numerous effects of the fast rotation of the progenitors: The neutron stars are aspherical; the ``nu_mu'' and anti-nu_e neutrino luminosities are reduced compared to the nu_e neutrino luminosity; the deleptonized region has a butterfly shape; the neutrino flux and electron fraction depend strongly upon latitude (a la von Zeipel); and a quasi-Keplerian 0.1-0.5-Msun accretion disk is formed.Comment: 25 pages, 19 figures, accpeted to ApJ, high resolution of the paper and movies available at http://hermes.as.arizona.edu/~luc/aic/aic.htm

High Diversity, Low Disparity and Small Body Size in Plesiosaurs (Reptilia, Sauropterygia) from the Triassic–Jurassic Boundary

Invasion of the open ocean by tetrapods represents a major evolutionary transition that occurred independently in cetaceans, mosasauroids, chelonioids (sea turtles), ichthyosaurs and plesiosaurs. Plesiosaurian reptiles invaded pelagic ocean environments immediately following the Late Triassic extinctions. This diversification is recorded by three intensively-sampled European fossil faunas, spanning 20 million years (Ma). These provide an unparalleled opportunity to document changes in key macroevolutionary parameters associated with secondary adaptation to pelagic life in tetrapods. A comprehensive assessment focuses on the oldest fauna, from the Blue Lias Formation of Street, and nearby localities, in Somerset, UK (Earliest Jurassic: 200 Ma), identifying three new species representing two small-bodied rhomaleosaurids (Stratesaurus taylori gen et sp. nov.; Avalonnectes arturi gen. et sp. nov) and the most basal plesiosauroid, Eoplesiosaurus antiquior gen. et sp. nov. The initial radiation of plesiosaurs was characterised by high, but short-lived, diversity of an archaic clade, Rhomaleosauridae. Representatives of this initial radiation were replaced by derived, neoplesiosaurian plesiosaurs at small-medium body sizes during a more gradual accumulation of morphological disparity. This gradualistic modality suggests that adaptive radiations within tetrapod subclades are not always characterised by the initially high levels of disparity observed in the Paleozoic origins of major metazoan body plans, or in the origin of tetrapods. High rhomaleosaurid diversity immediately following the Triassic-Jurassic boundary supports the gradual model of Late Triassic extinctions, mostly predating the boundary itself. Increase in both maximum and minimum body length early in plesiosaurian history suggests a driven evolutionary trend. However, Maximum-likelihood models suggest only passive expansion into higher body size categories

DNA Methylation Profiling Identifies Distinct Clusters in Angiosarcomas

Contains fulltext : 218858.pdf (Publisher’s version ) (Closed access)PURPOSE: DNA methylation profiling has previously uncovered biologically and clinically meaningful subgroups within many tumor types, but was not yet performed in angiosarcoma. Angiosarcoma is a rare sarcoma with very heterogeneous clinical presentations, which may be based on differences in biological background. In this exploratory study, DNA methylation profiling of 36 primary angiosarcoma samples from visceral, deep soft tissue, radiation-induced, and UV-induced localizations was performed. EXPERIMENTAL DESIGN: Primary angiosarcoma formalin-fixed paraffin-embedded samples from visceral, soft tissue, radiation-induced, and UV-induced origin were collected from a nationwide search for angiosarcoma in the Netherlands. DNA was extracted for methylation profiling with the Illumina Infinium MethylationEPIC array. Quality control assessment and unsupervised hierarchical clustering were performed. Copy-number profiles were generated and analyzed for chromosomal stability. Clinical data were obtained from the Netherlands Cancer Registry. RESULTS: DNA methylation profiling by unsupervised hierarchical clustering of 36 angiosarcoma samples (6 visceral, 5 soft tissue, 14 radiation-induced, 11 UV-induced) revealed two main clusters (A and B), which were divided into four subclusters. The clusters largely corresponded with clinical subtypes, showing enrichment of UV-induced cases in cluster A1 and radiation-induced cases in cluster A2. Visceral and soft tissue cases almost exclusively fell into cluster B. Cluster A showed significantly increased chromosomal instability and better overall survival (22 vs. 6 months, P = 0.046) compared with cluster B. CONCLUSIONS: In this novel methylation profiling study, we demonstrated for the first time four different angiosarcoma clusters. These clusters correlated with clinical subtype, overall survival, and chromosomal stability