279 research outputs found

    Implementing and optimizing the operation of membrane bioreactors for petroleum wastewater treatment

    Get PDF
    In the recent Kazakhstan Upstream Oil and Gas Technology and R&D Roadmap, water management has been recognized one of the fifteen main challenges that must be dealt with. This roadmap mentions that chemical processes are increasingly used for wastewater treatment; however it is recognized that "the preferred, longer term solution is likely to be membrane technology, which present a local R&D opportunity since further development is needed. This could lead to local opportunities for design, installation and maintenance of membrane separation equipment"[1]. In line with the above requirements the proposed project develops and optimizes a membrane based treatment scheme for the treating & recycling of the water within the industry. Another objective is to investigate several biological processes within the membrane bioreactor (MBR) including nitrification/denitrification and biological removal of cyanides

    Implementing and optimizing the operation of membrane bioreactors for petroleum wastewater treatment

    Get PDF
    In the recent Kazakhstan Upstream Oil and Gas Technology and R&D Roadmap, water management has been recognized one of the fifteen main challenges that must be dealt with. This roadmap mentions that chemical processes are increasingly used for wastewater treatment; however it is recognized that "the preferred, longer term solution is likely to be membrane technology, which present a local R&D opportunity since further development is needed. This could lead to local opportunities for design, installation and maintenance of membrane separation equipment"[1]. In line with the above requirements the proposed project develops and optimizes a membrane based treatment scheme for the treating & recycling of the water within the industry. Another objective is to investigate several biological processes within the membrane bioreactor (MBR) including nitrification/denitrification and biological removal of cyanides

    Noninvasive Ultrasound Monitoring of Embryonic and Fetal Development in Chinchilla lanigera to Predict Gestational Age: Preliminary Evaluation of This Species as a Novel Animal Model of Human Pregnancy

    Get PDF
    Ultrasound is a noninvasive routine method that allows real-time monitoring of fetal development in utero to determine gestational age and to detect congenital anomalies and multiple pregnancies. To date, the developmental biology of Chinchilla lanigera has not yet been characterized. This species has been found to undergo placentation, long gestation, and fetal dimensions similar to those in humans. The aim of this study was to assess the use of high-frequency ultrasound (HFUS) and clinical ultrasound (US) to predict gestational age in chinchillas and evaluate the possibility of this species as a new animal model for the study of human pregnancy. In this study, 35 pregnant females and a total of 74 embryos and fetuses were monitored. Ultrasound examination was feasible in almost all chinchilla subjects. It was possible to monitor the chinchilla embryo with HFUS from embryonic day (E) 15 to 60 and with US from E15 to E115 due to fetus dimensions. The placenta could be visualized and measured with HFUS from E15, but not with US until E30. From E30, the heartbeat became detectable and it was possible to measure fetal biometrics. In the late stages of pregnancy, stomach, eyes, and lenses became visible. Our study demonstrated the importance of employing both techniques while monitoring embryonic and fetal development to obtain an overall and detailed view of all structures and to recognize any malformation at an early stage. Pregnancy in chinchillas can be confirmed as early as the 15th day postmating, and sonographic changes and gestational age are well correlated. The quantitative measurements of fetal and placental growth performed in this study could be useful in setting up a database for comparison with human fetal ultrasounds. We speculate that, in the future, the chinchilla could be used as an animal model for the study of US in human pregnancy

    Outcome after Modified Maquet Procedure in dogs with unilateral cranial cruciate ligament rupture: Evaluation of recovery limb function by use of force plate gait analysis

    Get PDF
    Introduction Cranial cruciate ligament failure is one of the principal causes of canine lameness. Several surgical procedures were proposed to achieve joint stabilisation; among these, the Modified Maquet Procedure involves using a titanium foam wedge to achieve and maintain the tibial tuberosity advancement. The force-plate analysis provides to objectively assess normal and abnormal gait and the outcome of different surgical techniques. The study evaluates the outcome of limbs that underwent Modified Maquet Procedure using land-force plate analysis comparing the operated limb with its healthy contralateral one as a control. Materials and methods Thirty-five dogs with unilateral cranial cruciate ligament rupture were evaluated. Outcome after surgery was assessed by orthopaedic and radiographic evaluations and force plate gait analysis performed before surgery, at 15, 30 and 90 days after surgery. For objective comparison of ground reaction forces, data of operated limb were compared to contralateral limb on each time control and Symmetry Index at 90 days was determined. Healing radiographic signs, minor and major complication were reported. Results A significant improvement in ground reaction forces was reached in all the treated limbs between set time intervals. The median percentage increase in ground reaction forces was constant from 15 to 90 days, with a Symmetry Index >9 in 54.2% of patients suggesting a normal gait symmetry. A complete bone healing was noticed at 90 days follow-up radiographic assessment. We experienced three major (8.5%) and one minor (2.8%) complications. Conclusions To the Authors' knowledge, this is the first study in the veterinary literature that assessed outcomes of dogs undergoing Modified Maquet Procedure for the treatment of cranial cruciate ligament rupture using force plate gait analysis and healthy contralateral limb as a control group. Our results confirm that Modified Maquet Procedure is an effective method to stabilise the stifle joint

    Development of a Novel Process Integrating the Treatment of Sludge Reject Water and the Production of Polyhydroxyalkanoates (PHAs)

    Get PDF
    The Supporting Information is available free of charge on the ACS Publications website at DOI: https://doi.org/10.1021/acs.est.5b01776This study was carried out within the framework of the European projects LIVE WASTE (LIFE 12 ENV/CY/000544)

    Embracing additive manufacture: implications for foot and ankle orthosis design

    Get PDF
    <p>Abstract</p> <p>Background</p> <p>The design of foot and ankle orthoses is currently limited by the methods used to fabricate the devices, particularly in terms of geometric freedom and potential to include innovative new features. Additive manufacturing (AM) technologies, where objects are constructed via a series of sub-millimetre layers of a substrate material, may present the opportunity to overcome these limitations and allow novel devices to be produced that are highly personalised for the individual, both in terms of fit and functionality.</p> <p>Two novel devices, a foot orthosis (FO) designed to include adjustable elements to relieve pressure at the metatarsal heads, and an ankle foot orthosis (AFO) designed to have adjustable stiffness levels in the sagittal plane, were developed and fabricated using AM. The devices were then tested on a healthy participant to determine if the intended biomechanical modes of action were achieved.</p> <p>Results</p> <p>The adjustable, pressure relieving FO was found to be able to significantly reduce pressure under the targeted metatarsal heads. The AFO was shown to have distinct effects on ankle kinematics which could be varied by adjusting the stiffness level of the device.</p> <p>Conclusions</p> <p>The results presented here demonstrate the potential design freedom made available by AM, and suggest that it may allow novel personalised orthotic devices to be produced which are beyond the current state of the art.</p

    How a Diverse Research Ecosystem Has Generated New Rehabilitation Technologies: Review of NIDILRR’s Rehabilitation Engineering Research Centers

    Get PDF
    Over 50 million United States citizens (1 in 6 people in the US) have a developmental, acquired, or degenerative disability. The average US citizen can expect to live 20% of his or her life with a disability. Rehabilitation technologies play a major role in improving the quality of life for people with a disability, yet widespread and highly challenging needs remain. Within the US, a major effort aimed at the creation and evaluation of rehabilitation technology has been the Rehabilitation Engineering Research Centers (RERCs) sponsored by the National Institute on Disability, Independent Living, and Rehabilitation Research. As envisioned at their conception by a panel of the National Academy of Science in 1970, these centers were intended to take a “total approach to rehabilitation”, combining medicine, engineering, and related science, to improve the quality of life of individuals with a disability. Here, we review the scope, achievements, and ongoing projects of an unbiased sample of 19 currently active or recently terminated RERCs. Specifically, for each center, we briefly explain the needs it targets, summarize key historical advances, identify emerging innovations, and consider future directions. Our assessment from this review is that the RERC program indeed involves a multidisciplinary approach, with 36 professional fields involved, although 70% of research and development staff are in engineering fields, 23% in clinical fields, and only 7% in basic science fields; significantly, 11% of the professional staff have a disability related to their research. We observe that the RERC program has substantially diversified the scope of its work since the 1970’s, addressing more types of disabilities using more technologies, and, in particular, often now focusing on information technologies. RERC work also now often views users as integrated into an interdependent society through technologies that both people with and without disabilities co-use (such as the internet, wireless communication, and architecture). In addition, RERC research has evolved to view users as able at improving outcomes through learning, exercise, and plasticity (rather than being static), which can be optimally timed. We provide examples of rehabilitation technology innovation produced by the RERCs that illustrate this increasingly diversifying scope and evolving perspective. We conclude by discussing growth opportunities and possible future directions of the RERC program

    An advanced tool integrating failure and sensitivity analysis into novel modeling of the stormwater flood volume

    Get PDF
    An innovative tool for modeling the specific flood volume was presented that can be applied to assess the need for stormwater network modernization as well as for advanced flood risk assessment. Field measurements for a catchment area in Kielce, Poland, were used to apply the model and demonstrate its usefulness. This model extends the capability of recently developed statistical and machine learning hydrodynamic models developed from multiple runs of the US Environmental Protection Agency (EPA) Storm Water Management Model (SWMM). The extensions enable the inclusion of (1) the characteristics of the catchment and its stormwater network, calibrated model parameters expressing catchment retention, and the capacity of the sewer system; (2) extended sensitivity analysis; and (3) risk analysis. Sensitivity coefficients of calibrated model parameters include correction coefficients for percentage area, flow path, depth of storage, and impervious area; Manning roughness coefficients for impervious areas; and Manning roughness coefficients for sewer channels. Sensitivity coefficients were determined with respect to rainfall intensity and characteristics of the catchment and stormwater network. Extended sensitivity analysis enabled an evaluation of the variability in the specific flood volume and sensitivity coefficients within a catchment, in order to identify the most vulnerable areas threatened by flooding. Thus, the model can be used to identify areas particularly susceptible to stormwater network failure and the sections of the network where corrective action should be taken to reduce the probability of system failure. The simulator developed to determine the specific flood volume represents an alternative approach to the SWMM that, unlike current approaches, can be calibrated with limited topological data availability; therefore, the aforementioned simulator incurs a lower cost due to the lower number and lower specificity of data required.</p
    corecore