1,010 research outputs found
Employment relations via the web with international elements: Issues and proposals as to the applicable law and determination of jurisdiction in light of EU rules and principles
The article addresses the issues of which, from the EU perspective, are the applicable law and the competent courts in respect of employment contracts/relationships performed via the web and characterised by international elements. The study adopts a legal-regulatory approach, focusing, on one hand, on the issues related to the applicable law and, on the other hand, on those concerning the determination of the competent courts in respect of employment contracts/relationships performed via the web and characterised by international elements. The article outlines the
possible detrimental effects on the weaker party of the contractual relationship, deriving from the application of the current connecting factors based on EU rules and regulations, in respect of the applicable law and the competent courts. The article considers only the EU legal framework, but suggests an evolutionary interpretation of EU law, aimed at preserving the anti-dumping rationale underlying the legal regime governing the applicable law and investigates the potential of collective redress mechanisms
Super-hydrodynamic limit in interacting particle systems
This paper is a follow-up of the work initiated in [3], where it has been
investigated the hydrodynamic limit of symmetric independent random walkers
with birth at the origin and death at the rightmost occupied site. Here we
obtain two further results: first we characterize the stationary states on the
hydrodynamic time scale and show that they are given by a family of linear
macroscopic profiles whose parameters are determined by the current reservoirs
and the system mass. Then we prove the existence of a super-hyrdrodynamic time
scale, beyond the hydrodynamic one. On this larger time scale the system mass
fluctuates and correspondingly the macroscopic profile of the system randomly
moves within the family of linear profiles, with the randomness of a Brownian
motion.Comment: 22 page
Titanium nanotubes stimulate osteoblast differentiation of stem cells from pulp and adipose tissue
BACKGROUND:
Titanium is the gold standard among materials used for prosthetic devices because of its good mechanical and chemical properties. When exposed to oxygen, titanium becomes an oxide, anatase that is biocompatible and able to induce osseointegration.
MATERIALS AND METHODS:
IN THIS STUDY WE COMPARED THE EXPRESSION PROFILING OF STEM CELLS CULTIVATED ON TWO TYPES OF SURFACE: Pure titanium disk and nanotube titanium disk in order to detect if nanotube titanium instead (NTD) surface stimulates stem cells towards osteoblast differentiation.
RESULTS:
Stem cells cultivated on nanotube titanium disks showed the upregulation of bone-related genes RUNX2, FOSL1 and SPP1.
CONCLUSIONS:
Results demonstrated that nanotube titanium disk surface is more osteo-induced surface compared to titanium disk, promoting the differentiation of mesenchymal stem cells in osteoblasts
Duality relations for the ASEP conditioned on a low current
We consider the asymmetric simple exclusion process (ASEP) on a finite
lattice with periodic boundary conditions, conditioned to carry an atypically
low current. For an infinite discrete set of currents, parametrized by the
driving strength , , we prove duality relations which arise from
the quantum algebra symmetry of the generator of the
process with reflecting boundary conditions. Using these duality relations we
prove on microscopic level a travelling-wave property of the conditioned
process for a family of shock-antishock measures for particles: If the
initial measure is a member of this family with microscopic shocks at
positions , then the measure at any time of the process
with driving strength is a convex combination of such measures with
shocks at positions . which can be expressed in terms of
-particle transition probabilities of the conditioned ASEP with driving
strength .Comment: 26 page
I decreti attuativi del Jobs Act: prima lettura e interpretazioni. Commentario agli schemi di decreto legislativo presentati al Consiglio dei Ministri del 24 dicembre 2014 e alle disposizioni lavoristiche della legge di stabilitĂ
Con la trasmissione degli schemi di decreto legislativo approvati dal Consiglio dei Ministri dello scorso 24 dicembre alle Camere inizia il rush finale per l’approvazione dei primi tasselli del c.d. Jobs Act. Per accompagnare l’iter parlamentare ADAPT ha realizzato questo instant book, sulla base dei testi diffusi nei giorni successivi, messi ora a disposizione, nella consueta modalità open access, al fine di analizzare i principali nodi applicativi e di sistema che accompagneranno nelle prossime settimane gli interpreti e, soprattutto, le scelte di uomini e donne che ricoprono funzioni di gestione del personale e i loro consulenti giuridici. Per una corretta lettura dei primi commenti è opportuno segnalare ai lettori che, nel passaggio alle Camere, i testi dei decreti sono cambiati, quantomeno con riferimento al contratto di ricollocazione, che pure rappresentava parte rilevante della cifra riformista del Jobs Act, nello scambio tra nuove tutele e flessibilità in uscita dal mercato del lavoro. Da notizie ufficiose pare che comunque nulla cambi e che le disposizioni sul contratto di ricollocazione, ora stralciate dal decreto sulle tutele crescenti, troveranno presto spazio in un futuro decreto su servizi al lavoro e politiche attive. Anche per questa ragione il presente volume si basa sui testi dei decreti diffusi il 24 dicembre
Measurement of the neutron fields produced by a 62 MeV proton beam on a PMMA phantom using extended range Bonner sphere spectrometers
The experimental characterization of the neutron fields produced as parasitic effect in medical accelerators is assuming an increased importance for either the patient protection or the facility design aspects. Medical accelerators are diverse in terms of particle type (electrons or hadrons) and energy, but the radiation fields around them have in common (provided that a given threshold energy is reached) the presence of neutrons with energy span over several orders of magnitude. Due to the large variability of neutron energy, field or dosimetry measurements in these workplaces are very complex, and in general, cannot be performed with ready-to-use commercial instruments. In spite of its poor energy resolution, the Bonner Sphere Spectrometer (BSS) is the only instrument able to simultaneously determine all spectral components in such workplaces. The energy range of this instrument is limited to Eo 20 MeV if only polyethylene spheres are used, but can be extended to hundreds of MeV by including metal-loaded spheres (extended range BSS, indicated with ERBSS). With the aim of providing useful data to the scientific community involved in neutron measurements at hadron therapy facilities, an ERBSS experiment was carried out at the Centro di AdroTerapia e Applicazioni Nucleari Avanzate (CATANA) of INFN—LNS (Laboratori Nazionali del Sud), where a proton beam routinely used for ophthalmic cancer treatments is available. The 62 MeV beam was directed towards a PMMA phantom, simulating the patient, and two neutron measurement points wer
A new strategy against peri-implantitis: Antibacterial internal coating
The bacterial biofilm formation in the oral cavity and the microbial activity around the implant tissue represent a potential factor on the interface between bone and implant fixture that could induce an inflammatory phenomenon and generate an increased risk for mucositis and peri-implantitis. The aim of the present clinical trial was to investigate the bacterial quality of a new antibacterial coating of the internal chamber of the implant in vivo at six months. The PIXIT implant (Edierre srl, Genova Italy) is prepared by coating the implant with an alcoholic solution containing polysiloxane oligomers and chlorhexidine gluconate at 1%. A total of 15 healthy patients (60 implants) with non-contributory past medical history (nine women and six men, all non-smokers, mean age of 53 years, ranging from 45–61 years) were scheduled to receive bilateral fixed prostheses or crown restorations supported by an implant fixture. No adverse effects and no implant failure were reported at four months. All experimental sites showed a good soft tissue healing at the experimental point times and no local evidence of inflammation was observed. Real-Time Polymerase Chain Reaction (PCR) analysis on coated and uncoated implants showed a decrease of the bacterial count in the internal part of the implant chamber. The mean of total bacteria loading (TBL) detected in each PCR reaction was lower in treated implants (81,038 units/reaction) compared to untreated implants (90,057 units/reaction) (p < 0.01). The polymeric chlorhexydine coating of the internal chamber of the implant showed the ability to control the bacterial loading at the level of the peri-implant tissue. Moreover, the investigation demonstrated that the coating is able to influence also the quality of the microbiota, in particular on the species involved in the pathogenesis of peri-implantitis that are involved with a higher risk of long-term failure of the dental implant restoration
Association between oral cleft and transcobalamin 2 polymorphism in a sample study from Nassiriya, Iraq
Orofacial clefts are common congenital defects whose prevalence differs between geographical regions and ethnic groups. The inheritance is complex, involving the contribution of both genetic and environmental factors. The involvement of genes belonging to the folate pathway is still matter of debate, with strong evidences of association and conflicting results. After demonstrating the contribution, for a sample from the Italian population, of common mutations mapping on three genes of the folate pathway, our group tried to unravel their contribution in independent sample studies with different ethnicity. In the present investigation a set of 34 triads with oral cleft from Nassiriya, Iraq, has been genotyped for rs1801133 of MTHFR, rs1801198 of TCN2, and rs4920037 of CBS polymorphisms. Association analysis evidenced a decreased risk of cleft for children carrying the 667G allele at TCN2 gene (P = 0.02). This evidence further supported the relationship between polymorphisms of folate related genes and oral clefts, and outlined the relevance of studying populations having different ethnicity
Prevalence of Enterococci and Vancomycin Resistance in the Throat of Non-Hospitalized Individuals Randomly Selected in Central Italy
Enterococci are commonly found in the environment and humans as a part of the normal microbiota. Among these, Enterococcus faecalis and Enterococcus faecium can convert into opportunistic pathogens, making them a major cause of nosocomial infections. The rapid diffusion of vancomycin-resistant strains and their impact on nosocomial settings is of considerable concern. Approximately one-third of the E. faecium infections in Italy are caused by vancomycin-resistant strains. This study explored the hypothesis that the oral cavity could represent a silent reservoir of virulent enterococci. A sample of 862 oral flora specimens collected from healthy human volunteers in Central Italy was investigated by real-time PCR to detect E. faecalis and E. faecium, as well as the genetic elements that most frequently determine vancomycin resistance. The prevalence of E. faecalis was 19%, a value that was not associated with alcohol consumption, tobacco smoking, or age of the subjects. Less frequently detected, with an overall prevalence of 0.7%, E. faecium was more common among people older than 49 years of age. The genes conferring vancomycin resistance were detected in only one sample. The results indicate that the oral cavity can be considered a reservoir of clinically relevant enterococci; however, our data suggest that healthy individuals rarely carry vancomycin-resistant strains
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