Using corrugation stitch in submammary fold at the reconstructive breast surgery

The aim of the research was to develop a new technique for suturing the surgical incision in submammary area after subpectoral reconstructive breast surgery with good cosmetic result. Clinical observation group included 10 patients. It was found that the new technique of suturing the surgical incision, in comparison with the method offered by M.B. Calobrace et al. (2014), allows to decrease the duration of suturing from 6 min 10 ± 0.06 sec down to 5 min 29 ± 0.04 sec (р < 0.01), to reduce number of stitches from 24 down to 15, to shorten postoperative stitch from 4.24 ± 0.06 cm down to 3.71 ± 0.07 cm (р < 0.01), and to shorten cicatrix length in 1 year after the operation from 4.78 ± 0.19 cm down to 4.25 ± 0.22 cm (р < 0.05). Therefore, the developed technique of suturing the surgical wound provides the location of postoperative cicatrix in the area of submammary fold which makes it less noticeable. Moreover, it allows to shorten the length of postoperative cicatrix, decrease the duration of the surgery and to secure adequate stability of implant fixation

КОНТРОЛЬ ОСТАТОЧНЫХ НАПРЯЖЕНИЙ В СТРУКТУРАХ SI-SIO2

The consideration is made of the ways leading to increasing the control of residual stresses in structures such as silicon dioxide-monocrystal silicon substrate. The results concerning the determination of the level of residual stresses in structures Si-SiO2 are presented.Рассмотрены пути повышения точности контроля величины остаточных напряжений в структурах диоксид кремния-монокристаллическая кремниевая подложка. Приведены результаты определения уровня остаточных напряжений в структурах Si-SiO2

Dynamic tests of multi-detector radiometric system on central blood circulation phantom

Phantoms of organs and biological systems are widely used for verification of radioisotope protocols. The construction and operation of the heart and circulation phantom is described. The present model was designed for experimental testing of multi-detector radiometric system, prototype of which was designed in Ural Federal University as an extension and alternative to Anger camera and single-photon-emission tomography radionuclide diagnostics. The model represents vital dynamic properties of the single-chamber pulsing heart and circulation, featuring adjustable heart rate, blood volume, ejection fraction and flowrate. The trial experiments were performed with 99m Tc-pertechnetate to obtain time-activity curves and the ejection fraction was thus measured basing on first-pass radio angiography technique. © Published under licence by IOP Publishing Ltd

Copper Inhibits the Water and Glycerol Permeability of Aquaporin-3

Aquaporin-3 (AQP3) is an aquaglyceroporin expressed in erythrocytes and several other tissues. Erythrocytes are, together with kidney and liver, the main targets for copper toxicity. Here we report that both water and glycerol permeability of human AQP3 is inhibited by copper. Inhibition is fast, dose-dependent, and reversible. If copper is dissolved in carbonic acid-bicarbonate buffer, the natural buffer system in our body, doses in the range of those observed in Wilson disease and in copper poisoning caused significant inhibition. AQP7, another aquaglyceroporin, was insensitive to copper. Three extracellular amino acid residues, Trp128, Ser152, and His241, were identified as responsible for the effect of copper on AQP3. We have previously shown that Ser152 is involved in regulation of AQP3 by pH. The fact that Ser152 mediates regulation of AQP3 by copper may explain the phenomenon of exquisite sensitivity of human erythrocytes to copper at acidic pH. When AQP3 was co-expressed with another AQP, only glycerol but not water permeability was inhibited by copper. Our results provide a better understanding of processes that occur in severe copper metabolism defects such as Wilson disease and in copper poisoning

Developing the structure of the personality's ecological culture

The article is devoted to a detailed analysis of the personality's ecological cultureand the description of its components. The author systematizes the elements of ecological culture, selected and described by modern researchers in the field of forming ecological culture and environmental consciousness of the person, systematizes them and establishes a functional relationship between them. The author considers the implementation of personal ecologically oriented activities to be the main purpose of forming ecological culture; therefore, the author proposes to enlarge the structure of ecological culture under consideration with such elements, as expert opinions and scientific environmental assessment (expert review). Copyright@ EM International

Dynamic Coupling Between Links Of Articulated Transport Systems

The issues of improving the operational properties of transport systems are considered. Various ways to improve productivity, economic and environmental performance, operational reliability, as well as improve and automate the transport system controls are shown. One of the most important issues in the theory of movement, i.e., the effective distribution of the power flow between the drive axles and sections is considered. The coupling between the transport system links is estimated. The coupling between the links of active articulated multi-section machines has been analyzed based on various variants of the kinematic misalignment in the drive. The state graph of a two-section active articulated transport and production machine is considered. The coupling between the links of the articulated transport system is considered and formalized for the pole trailer supported simultaneously by two or more machine sections. The areas of further link coupling analysis based on the state graph of a two-section active articulated transport system are determined. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG

ORTHOTOPIC INTESTINOPLASTY OF URINARY BLADDER - A COMPLEX APPROACH

We analyzed the results of treatment of 57 patients who had. cystectomy with forming of orthotopic cystoplastte urinary bladder. Cystoplastis was performed by the original method. The approach to the choice of method, for creating orthotopic bladder was complex. Take into account the length of ileum resection, the technique of formation and the shape of the bladder, pre-calculated volume of orthotopic urinary bladder technique was used to create antireflux ureteral-intestinal anastomosis. Such an approach to reduce the risk of postoperative complications and to maintain the high, quality of life for patients

COMPLiCATiONS AFTER CYSTECTOMY AND THEiR TREATMENT

We analyzed the results of treatment of 110 patients who had. cystectomy with, different types of urinary diversion. In the early postoperative period next complications occurred: prolonged intestinal paresis, dynamic ileus, thrombosis of the external iliac artery failure of intestinal anastomosis and the uretero-reservoir anastomosis, lymphocele formation, exacerbation of chronic pyelonephritis. In the late postoperative major complications were: urinary incontinence, stricture of the uretero-reservoir anastomosis, bladder stone formation. Conducted. operational and conservative methods of treatment allowed the arrest caused complications

Genomic sequencing and biological characteristics of a novel Escherichia Coli bacteriophage 9g, a putative representative of a new siphoviridae genus

© 2014 by the authors; licensee MDPI, Basel, Switzerland. Bacteriophage 9g was isolated from horse feces using Escherichia coli C600 as a host strain. Phage 9g has a slightly elongated capsid 62 × 76 nm in diameter and a non-contractile tail about 185 nm long. The complete genome sequence of this bacteriophage consists of 56,703 bp encoding 70 predicted open reading frames. The closest relative of phage 9g is phage PhiJL001 infecting marine alpha-proteobacterium associated with Ircinia strobilina sponge, sharing with phage 9g 51% of amino acid identity in the main capsid protein sequence. The DNA of 9g is resistant to most restriction endonucleases tested, indicating the presence of hypermodified bases. The gene cluster encoding a biosynthesis pathway similar to biosynthesis of the unusual nucleoside queuosine was detected in the phage 9g genome. The genomic map organization is somewhat similar to the typical temperate phage gene layout but no integrase gene was detected. Phage 9g efficiently forms stable associations with its host that continues to produce the phage over multiple passages, but the phage can be easily eliminated via viricide treatment indicating that no true lysogens are formed. Since the sequence, genomic organization and biological properties of bacteriophage 9g are clearly distinct from other known Enterobacteriaceae phages, we propose to consider it as the representative of a novel genus of the Siphoviridae family

Conditionally university student readiness of the person to self-development by means of physical education

The article discusses conditionality desire of students to self-development and the formation of competence readiness in this area of knowledge in classes of P.E. Designed levels determination of formation of readiness for self-development of students of the university. The system contributes to self-realization of the personality of students, formation of physical culture and sports competences and the competence of self-development. The fact is that the current situation in the development of the society and the analysis of the world's sociocultural and educational trends indicate that in recent years, various aspects of the individual's behavior towards his health have become the object of intense public attention and the subject of interdisciplinary research in many highly developed countries under the slogan: "Health is not everything, but everything without health is nothing". Hence the tasks of the student's personality self-development during the intensive preparation for professional activity at the university are aimed at maintaining their own health and improving their physical fitness, considering formation of professional motor skills for effective mastering the future profession and career growth after graduation.peer-reviewe