14,270 research outputs found
Tiltrotor CFD part II: aerodynamic optimisation of tiltrotor blades
This paper presents aerodynamic optimisation of tiltrotor blades with high-fidelity computational
fluid dynamics. The employed optimisation framework is based on a quasi-Newton
method, and the required high-fidelity flow gradients were computed using a discrete adjoint
solver. Single-point optimisations were first performed, to highlight the contrasting requirements
of the helicopter and aeroplane flight regimes. It is then shown how a trade-off blade
design can be obtained using a multi-point optimisation strategy. The parametrisation of the
blade shape allowed to modify the twist and chord distributions, and to introduce a swept tip.
The work shows how these main blade shape parameters influence the optimal performance
of the tiltrotor in helicopter and aeroplane modes, and how a compromise blade shape can
increase the overall tiltrotor performance. Moreover, in all the presented cases, the accuracy
of the adjoint gradients resulted in a small number of flow evaluations for finding the optimal
solution, thus indicating gradient-based optimisation as a viable tool for modern tiltrotor
design
Immunopathogenesis of canine chronic ulcerative stomatitis.
Canine Chronic Ulcerative Stomatitis is a spontaneously occurring inflammatory disease of the oral mucosa. An immune-mediated pathogenesis is suspected though not yet proven. We have recently reported on the clinical and histologic features, and identification of select leukocyte cell populations within the lesion. A clinical and histologic similarity to oral lichen planus of people was proposed. In the present study, these initial observations are extended by examining lesions from 24 dogs with clinical evidence of chronic ulcerative stomatitis. Because dogs with chronic ulcerative stomatitis often have concurrent periodontal disease, we wondered if dental plaque/biofilm may be a common instigator of inflammation in both lesions. We hypothesized that dogs with chronic ulcerative stomatitis would exhibit a spectrum of pathologic changes and phenotype of infiltrating leukocytes that would inform lesion pathogenesis and that these changes would differ from inflammatory phenotypes in periodontitis. Previously we identified chronic ulcerative stomatitis lesions to be rich in FoxP3+ and IL17+ cells. As such, we suspect that these leukocytes play an important role in lesion pathogenesis. The current study confirms the presence of moderate to large numbers of FoxP3+ T cells and IL17+ cells in all ulcerative stomatitis lesions using confocal immunofluorescence. Interestingly, the majority of IL17+ cells were determined to be non-T cells and IL17+ cell frequencies were negatively correlated with severity on the clinical scoring system. Three histologic subtypes of ulcerative stomatitis were determined; lichenoid, deep stomatitis and granulomatous. Periodontitis lesions, like stomatitis lesions, were B cell and plasma cell rich, but otherwise differed from the stomatitis lesions. Direct immunofluorescence results did not support an autoantibody-mediated autoimmune disease process. This investigation contributes to the body of literature regarding leukocyte involvement in canine idiopathic inflammatory disease pathogenesis
The Cosmic Neutrino Background and the Age of the Universe
We discuss the cosmological degeneracy between the age of the Universe, the
Hubble parameter and the effective number of relativistic particles N_eff. We
show that independent determinations of the Hubble parameter H(z) as those
recently provided by Simon,Verde, Jimenez (2006), combined with other
cosmological data sets can provide the most stringent constraint on N_eff,
yielding N_eff=3.7 (-1.2) (+1.1) at 95% confidence level. A neutrino background
is detected with high significance: N_eff >1.8 at better than 99% confidence
level. Constraints on the age of the universe in the framework of an extra
background of relativistic particles are improved by a factor 3.Comment: JCAP, in pres
Space Station Freedom photovoltaic power module design status
Electric power generation for Space Station Freedom will be provided by four photovoltaic (PV) power modules using silicon solar cells during Phase 1 operation. Each PV power module requires two solar arrays with 32,800 solar cells generating 18.75 kW of dc power for a total of 75 kW. A portion of this power will be stored in nickel-hydrogen batteries for use during eclipse, and the balance will be processed and converted to 20 kHz ac power for distribution to end users through the power management and distribution system. The design incorporates an optimized thermal control system, pointing and tracking provision with the application of gimbals, and the use of orbital replacement units (ORU's) to achieve modularization. Design status of the PV power module, as derived from major trade studies, is discussed at hardware levels ranging from component to system. Details of the design are presented where appropriate
Detection of periodic signatures in the solar power spectrum. On the track of l=1 gravity modes
In the present work we show robust indications of the existence of g modes in
the Sun using 10 years of GOLF data. The present analysis is based on the
exploitation of the collective properties of the predicted low-frequency (25 to
140 microHz) g modes: their asymptotic nature, which implies a quasi
equidistant separation of their periods for a given angular degree (l). The
Power Spectrum (PS) of the Power Spectrum Density (PSD), reveals a significant
structure indicating the presence of features (peaks) in the PSD with near
equidistant periods corresponding to l=1 modes in the range n=-4 to n=-26. The
study of its statistical significance of this feature was fully undertaken and
complemented with Monte Carlo simulations. This structure has a confidence
level better than 99.86% not to be due to pure noise. Furthermore, a detailed
study of this structure suggests that the gravity modes have a much more
complex structure than the one initially expected (line-widths, magnetic
splittings...). Compared to the latest solar models, the obtained results tend
to favor a solar core rotating significantly faster than the rest of the
radiative zone. In the framework of the Phoebus group, we have also applied the
same methodology to other helioseismology instruments on board SoHO and ground
based networks.Comment: Proceedings of the SOHO-18/GONG2006/HELAS I: Beyond the spherical Su
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