World market or regional integration and food security in West Africa

The problem of food security in West Africa was put on the international agenda in 1974 at the international food conference in Rome following the Great Sahelian Drought of 1968-1973. In those years preoccupation with food security was limited mainly to the Sahel countries and concentrated on estimating the availability and use of resources for grain production. Nowadays, studies in the field of food security focus not only on production, but also on the functioning of the food market, and on consumption and nutrition. This paper concentrates on the debate whether sustainable food security in West Africa will be achieved by protection measures for national food production, by a liberalization of the food trade that facih'tates cheap imports of food from the world market, or by stimulating regional food trade through regional co-operation

Regional food trade and policy in West Africa in relation to structural adjustment

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Comparison between land suitability and actual crop distribution in an irrigation district of the Ebro valley (Spain)

El objetivo de la presente investigación fue analizar la correspondencia entre los resultados de una evaluación de tierras con la distribución real de los cultivos. Para ello la aptitud biofísica de las tierras se comparó con diferentes tipologías de frecuencia de ocurrencia de los cultivos y rotaciones derivadas de mapas de cultivos multitemporales. La investigación fue llevada a cabo en el distrito de riego de Flumen (33.000 ha), localizado en el valle del Ebro (NE España). La evaluación de tierras se basó en una cartografía de suelos 1:100.000, según el esquema FAO, para los principales cultivos presentes en el área de estudio (alfalfa, cereales de invierno, maíz, arroz y girasol). Se utilizaron tres mapas de frecuencia de cultivos y un mapa de rotaciones, derivado de una serie temporal de imágenes Landsat TM y ETM+ del periodo 1993-2000, y se compararon con los mapas de aptitud de tierras para los diferentes cultivos. Se analizó estadísticamente (Pearson χ2, Cramer V, Gamma y Somers D) la relación entre los dos tipos de variables. Los resultados muestran la existencia de una relación significativa (P=0,001) entre la localización de los cultivos y la idoneidad de las tierras, excepto de cultivos oportunistas como el girasol, muy influenciado por las subvenciones en el periodo estudiado. Las rotaciones basadas en la alfalfa muestran los mayores porcentajes (52%) de ocupación en las tierras más aptas para la agricultura en el área de estudio. El presente enfoque multitemporal de análisis de la información ofrece una visión más real que la comparación entre un mapa de evaluación de tierras y un mapa de cultivos de una fecha determinada, cuando se valora el grado de acuerdo entre las recomendaciones sobre la aptitud de las tierras y los cultivos realmente cultivados por los agricultores.The present research aims to obtain a better insight into the agreement between land evaluation results and actual crop spatial distribution by comparing biophysical land suitability with different crop frequency parameters and with crop rotations derived from multi-year crop maps. The research was carried out in the Flumen district (33,000 ha), which is located in the Ebro Valley (northeast Spain). Land evaluation was based on a 1:100,000 soil survey according to the FAO framework for the main crops in the study area (alfalfa, winter cereals, maize, rice and sunflower). Three crop frequency maps and a crop rotation map, derived from a time-series of Landsat TM and ETM+ images of the period 1993-2000 were used for comparison with land suitability maps. The relationships between the two types of variables were analyzed by means of statistical tests (Pearson chi-square (χ2), Cramer ́s V, Gamma and Somers ́ D). The results show the existence of a significant (P=0.001) relationship between crops’ location and land suitability, except for opportunist crops as sunflower, which is very much influenced by subsidies in the study period. The alfalfa-based rotations show the highest distribution percentages (52%) on the land most suitable for agriculture in the area. The present multitemporal analysis approach offers a more realistic insight than the comparison between a land evaluation map and static year crop map in assessing the degree of agreement of land evaluation recommendations with crops actually cultivated by farmers

Possible Heavy-Fermion Behaviour of New U(Cu, Al)5 Compounds

We have synthesized several new UCuxAl5 - x compounds in the composition range between x = 2.9 and x = 3.5, which were found to form in crystal structures related to the CaCu5 structure. Specific-heat measurements reveal a considerable enhancement of the low-temperature specific-heat coefficient γ for all U(Cu, Al)5 compounds investigated, with a maximum value of 450 mJ/molK2 at 1.2 K for UCu2.9Al2.1. © 1995.Acknowledgement: Work was supported by the "Sticht-ing voor Fundamenteel Onderzoek der Materie" (FOM)

The superconducting ferromagnet UCoGe

The correlated metal UCoGe is a weak itinerant ferromagnet with a Curie temperature T_C = 3 K and a superconductor with a transition temperature T_s = 0.6 K. We review its basic thermal, magnetic - on the macro and microscopic scale - and transport properties, as well as the response to high pressure. The data unambiguously show that superconductivity and ferromagnetism coexist below T_s = 0.6 K and are carried by the same 5f electrons. We present evidence that UCoGe is a p-wave superconductor and argue that superconductivity is mediated by critical ferromagnetic spin fluctuations.Comment: 19 pages; review paper; accepted for publication in the Journal of Low Temperature Physics (Special issue: Quantum Phase Transitions 2010

Putative role of the adenosine A3 receptor in the antiproliferative action of N6-(2-isopentenyl)adenosine

We tested a panel of naturally occurring nucleosides for their affinity towards adenosine receptors. Both N6-(2-isopentenyl)adenosine (IPA) and racemic zeatin riboside were shown to be selective human adenosine A3 receptor (hA3R) ligands with affinities in the high nanomolar range (Ki values of 159 and 649 nM, respectively). These values were comparable to the observed Ki value of adenosine on hA3R, which was 847 nM in the same radioligand binding assay. IPA also bound with micromolar affinity to the rat A3R. In a functional assay in Chinese hamster ovary cells transfected with hA3R, IPA and zeatin riboside inhibited forskolin-induced cAMP formation at micromolar potencies. The effect of IPA could be blocked by the A3R antagonist VUF5574. Both IPA and reference A3R agonist 2-chloro-N6-(3-iodobenzyl)adenosine-5′-N-methylcarboxamide (Cl-IB-MECA) have known antitumor effects. We demonstrated strong and highly similar antiproliferative effects of IPA and Cl-IB-MECA on human and rat tumor cell lines LNCaP and N1S1. Importantly, the antiproliferative effect of low concentrations of IPA on LNCaP cells could be fully blocked by the selective A3R antagonist MRS1523. At higher concentrations, IPA appeared to inhibit cell growth by an A3R-independent mechanism, as was previously reported for other A3R agonists. We used HPLC to investigate the presence of endogenous IPA in rat muscle tissue, but we could not detect the compound. In conclusion, the antiproliferative effects of the naturally occurring nucleoside IPA are at least in part mediated by the A3R

Functional selectivity of adenosine receptor ligands

Adenosine receptors are plasma membrane proteins that transduce an extracellular signal into the interior of the cell. Basically every mammalian cell expresses at least one of the four adenosine receptor subtypes. Recent insight in signal transduction cascades teaches us that the current classification of receptor ligands into agonists, antagonists, and inverse agonists relies very much on the experimental setup that was used. Upon activation of the receptors by the ubiquitous endogenous ligand adenosine they engage classical G protein-mediated pathways, resulting in production of second messengers and activation of kinases. Besides this well-described G protein-mediated signaling pathway, adenosine receptors activate scaffold proteins such as β-arrestins. Using innovative and sensitive experimental tools, it has been possible to detect ligands that preferentially stimulate the β-arrestin pathway over the G protein-mediated signal transduction route, or vice versa. This phenomenon is referred to as functional selectivity or biased signaling and implies that an antagonist for one pathway may be a full agonist for the other signaling route. Functional selectivity makes it necessary to redefine the functional properties of currently used adenosine receptor ligands and opens possibilities for new and more selective ligands. This review focuses on the current knowledge of functionally selective adenosine receptor ligands and on G protein-independent signaling of adenosine receptors through scaffold proteins