2,631 research outputs found
Polariton Squeezing in Semiconductor Microcavities
We report squeezed polariton generation using parametric polariton four-wave
mixing in semiconductor microcavities in the strong coupling regime. The
geometry of the experiment corresponds to degenerate four-wave mixing, which
gives rise to a bistability threshold. Spatial effects in the nonlinear regime
are evidenced, and spatial filtering is required in order to optimize the
measured squeezing. By measuring the noise of the outgoing light, we infer a 9
percent squeezing on the polariton field close to the bistability turning
point
Twin polaritons in semiconductor microcavities
The quantum correlations between the beams generated by polariton pair
scattering in a semiconductor microcavity above the parametric oscillation
threshold are computed analytically. The influence of various parameters like
the cavity-exciton detuning, the intensity mismatch between the signal and
idler beams and the amount of spurious noise is analyzed. We show that very
strong quantum correlations between the signal and idler polaritons can be
achieved. The quantum effects on the outgoing light fields are strongly reduced
due to the large mismatch in the coupling of the signal and idler polaritons to
the external photons
Signatures of the Youngest Starbursts: Optically-thick Thermal Bremsstrahlung Radio Sources in Henize 2-10
VLA radio continuum imaging reveals compact (<8 pc) ~1 mJy radio sources in
the central 5" starburst region of the blue compact galaxy Henize 2-10. We
interpret these radio knots as extremely young, ultra-dense HII regions. We
model their luminosities and spectral energy distributions, finding that they
are consistent with unusually dense HII regions having electron densities, 1500
cm^-3 < n_e < 5000 cm^-3, and sizes of 3-8 pc. Since these H II regions are not
visible in optical images, we propose that the radio data preferentially reveal
the youngest, densest, and most highly obscured starforming events. Energy
considerations imply that each of the five \HII regions contains ~750 O7V
equivalent stars, greater than the number found in 30 Doradus in the LMC. The
high densities imply an over-pressure compared to the typical interstellar
medium so that such objects must be short-lived (<0.5 Myr expansion
timescales). We conclude that the radio continuum maps reveal the very young
(<0.5 Myr) precursors of ``super starclusters'' or ``proto globular clusters''
which are prominent at optical and UV wavelengths in He 2-10. If the
ultra-dense HII regions are typical of those which we predict will be found in
other starbursting systems, then super starclusters spend 15% of their lifetime
in heavily-obscured environments, similar to Galactic ultra-compact HII
regions. This body of work leads us to propose that massive extragalactic star
clusters (i.e. proto globular clusters) with ages <10^6 yr may be most easily
identified by finding compact radio sources with optically-thick thermal
bremsstrahlung spectral signatures.Comment: AASTeX, 8 figures 2 included with psfig in text; other 6 in jpeg
format; Postscript versions of figures may be found at
http://zem.ucolick.org/chip/Research/young_clusters.html -- Accepted for
publication in the Astrophysical Journa
Mechanical testing ontology for digital-twins: A roadmap based on EMMO
The enormous amount of materials data currently generated by high throughput experiments and computations poses a significant challenge in terms of data integration and sharing. A common ontology lays the foundation for solving this issue, enabling semantic interoperability of models, experiments, software and data which is vital for a more rational and efficient development of novel materials. This paper is based on the current efforts by the European Materials Modelling Council (EMMC) on establishing common standards for materials through the European Materials & Modelling Ontology (EMMO) and demonstrates the application of EMMO to the mechanical testing field. The focus of this paper is to outline the approach to develop EMMO compliant domain ontologies
The role of microtubule movement in bidirectional organelle transport
We study the role of microtubule movement in bidirectional organelle
transport in Drosophila S2 cells and show that EGFP-tagged peroxisomes in cells
serve as sensitive probes of motor induced, noisy cytoskeletal motions.
Multiple peroxisomes move in unison over large time windows and show
correlations with microtubule tip positions, indicating rapid microtubule
fluctuations in the longitudinal direction. We report the first high-resolution
measurement of longitudinal microtubule fluctuations performed by tracing such
pairs of co-moving peroxisomes. The resulting picture shows that
motor-dependent longitudinal microtubule oscillations contribute significantly
to cargo movement along microtubules. Thus, contrary to the conventional view,
organelle transport cannot be described solely in terms of cargo movement along
stationary microtubule tracks, but instead includes a strong contribution from
the movement of the tracks.Comment: 24 pages, 5 figure
Photodynamic therapy as adjuvant therapy in surgically treated pleural malignancies.
Five patients with a pleural malignancy (four malignant mesotheliomas and one localized low grade carcinoid) were treated with maximal surgical resection of the tumour followed by intraoperative adjuvant photodynamic therapy (PDT). The additional photodynamic treatment was performed with light of 652 nm from a high power diode laser, and meta-tetrahydroxy phenylchlorin as the photosensitizer. The light delivery to the thoracic cavity was monitored by in situ isotropic light detectors. The position of the light delivery fibre was adjusted to achieve optimal light distribution, taking account of reflected and scattered light in this hollow cavity. There was no 30-day post-operative mortality and only one patient suffered from a major complication (diaphragmatic rupture and haematopericardium). The operation time was increased by a maximum of 1 h to illuminate the total hemithoracic surface with 10 J cm(-2) (incident and scattered light). The effect of the adjuvant PDT was monitored by examination of biopsies taken 24 h after surgery under thoracoscopic guidance. Significant damage, including necrosis, was observed in the marker lesions with remaining malignancy compared with normal tissue samples, which showed only an infiltration with PMN cells and oedema of the striated muscles cells. Of the five patients treated, four are alive with no signs of recurrent tumour with a follow-up of 9-11 months. One patient was diagnosed as having a tumour dissemination in the skin around the thoracoscopy scar and died of abdominal tumour spread. Light delivery to large surfaces for adjuvant PDT is feasible in a relatively short period of time (< 1 h). In situ dosimetry ensures optimal light distribution and allows total doses (incident plus scattered light) to be monitored at different positions within the cavity. This combination of light delivery and dosimetry is well suited for adjuvant treatment with PDT in malignant pleural tumours
Extending standard testing period in honeybees to predict lifespan impacts of pesticides and heavy metals using dynamic energy budget modelling
Concern over reported honeybee (Apis mellifera spp.) losses has highlighted chemical exposure as a risk. Current laboratory oral toxicity tests in A. mellifera spp. use short-term, maximum 96 hour, exposures which may not necessarily account for chronic and cumulative toxicity. Here, we use extended 240 hour (10 day) exposures to examine seven agrochemicals and trace environmental pollutant toxicities for adult honeybees. Data were used to parameterise a dynamic energy budget model (DEBtox) to further examine potential survival effects up to 30 day and 90 day summer and winter worker lifespans. Honeybees were most sensitive to insecticides (clothianidin > dimethoate ≫ tau-fluvalinate), then trace metals/metalloids (cadmium, arsenic), followed by the fungicide propiconazole and herbicide 2,4-dichlorophenoxyacetic acid (2,4-D). LC50s calculated from DEBtox parameters indicated a 27 fold change comparing exposure from 48 to 720 hours (summer worker lifespan) for cadmium, as the most time-dependent chemical as driven by slow toxicokinetics. Clothianidin and dimethoate exhibited more rapid toxicokinetics with 48 to 720 hour LC50s changes of <4 fold. As effects from long-term exposure may exceed those measured in short-term tests, future regulatory tests should extend to 96 hours as standard, with extension to 240 hour exposures further improving realism
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Women's views of continuity of information provided during and after pregnancy: A qualitative interview study
Straightforward transfer of care from pregnancy to the postpartum period is associated with health benefits and is desired by women worldwide. Underpinning this transfer of care is the sharing of information between healthcare professionals and the provision of consistent information to women. In this qualitative study, two aspects of continuity of information were examined; first the information passed on from midwife to health visitor regarding a woman and her baby before the health visitor meets the woman postnatally and second, the consistency of information received by women from these two healthcare professionals (the main healthcare providers during and after pregnancy in England). To be eligible for the study, women had to have had a baby in England within 12Â months prior to the interview. Participants also needed to be able to read and speak English and be over 18Â years old. Recruitment of participants was via word of mouth and social media. Twenty-nine mothers were interviewed of whom 19 were first time mothers. The interviews took place in the summer and autumn of 2016 and were transcribed verbatim and analysed using Framework Analysis. Two overarching themes were identified: not feeling listened to and information inconsistencies. Women reported little experience of midwives and health visitors sharing information about their care, forcing women to repeat information. This made women feel not listened to and participants recommended that healthcare professionals share information; prioritising information about labour, mental health, and chronic conditions. Women had mixed experiences regarding receiving information from midwives and health visitors, with examples of both consistent and inconsistent information received. To avoid inconsistent information, joint appointments were recommended. Findings from this study clearly suggest that better communication pathways need to be developed and effectively implemented for midwives and health visitors to improve the care that they provide to women
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