Effect of dissipation and measurement on a tunneling system

We consider a parametrically driven Kerr medium in which the pumping may be sinusoidally varied. It has been previously found that this system exhibits coherent tunneling between two fixed points which can be either enhanced or suppressed by altering the driving frequency and strength. We numerically investigate the dynamics when damping is included. This is done both by solving a master equation and using the quantum-trajectory method. In the latter case it is also possible to model the result of a continuous heterodyne measurement of the cavity output. The dissipation destroys the coherences which give rise to the tunneling, causing the sinusoidal oscillation of the mean to give way to a stochastic jumping between the fixed points, manifested as a random telegraph signal. In the quantum-trajectory picture we show that the coherences responsible for tunneling are an exponentially decreasing function of the signal-to-noise ratio for heterodyne measurements. However, evidence of both the bare tunneling rate and the driving modified tunneling rate are still apparent in the random telegraph signal

Entanglement of coherent states and decoherence

A possibility to produce entangled superpositions of strong coherent states is discussed. A recent proposal by Howell and Yazell [Phys. Rev. A 62, 012102 (2000)] of a device which entangles two strong coherent coherent states is critically examined. A serious flaw in their design is found. New modified scheme is proposed and it is shown that it really can generate non-classical states that can violate Bell inequality. Moreover, a profound analysis of the effect of losses and decoherence on the degree of entanglement is accomplished. It reveals the high sensitivity of the device to any disturbances and the fragility of generated states

Detection of Coxiella burnetii in complex matrices by using multiplex quantitative PCR during a major Q fever outbreak in the Netherlands

Q fever, caused by Coxiella burnetii, is a zoonosis with a worldwide distribution. A large rural area in the southeast of the Netherlands was heavily affected by Q fever between 2007 and 2009. This initiated the development of a robust and internally controlled multiplex quantitative PCR (qPCR) assay for the detection of C. burnetii DNA in veterinary and environmental matrices on suspected Q fever-affected farms. The qPCR detects three C. burnetii targets (icd, com1, and IS1111) and one Bacillus thuringiensis internal control target (cry1b). Bacillus thuringiensis spores were added to samples to control both DNA extraction and PCR amplification. The performance of the qPCR assay was investigated and showed a high efficiency; a limit of detection of 13.0, 10.6, and 10.4 copies per reaction for the targets icd, com1, and IS1111, respectively; and no crossreactivity with the nontarget organisms tested. Screening for C. burnetii DNA on 29 suspected Q fever-affected farms during the Q fever epidemic in 2008 showed that swabs from dust-accumulating surfaces contained higher levels of C. burnetii DNA than vaginal swabs from goats or sheep. PCR inhibition by coextracted substances was observed in some environmental samples, and 10- or 100-fold dilutions of samples were sufficient to obtain interpretable signals for both the C. burnetii targets and the internal control. The inclusion of an internal control target and three C. burnetii targets in one multiplex qPCR assay showed that complex veterinary and environmental matrices can be screened reliably for the presence of C. burnetii DNA during an outbreak. © 2011, American Society for Microbiology

Genotyping of Giardia in Dutch patients and animals: a phylogenetic analysis of human and animal isolates.

Giardia duodenalis (syn. Giardia lamblia, Giardia intestinalis) is a protozoan organism that can infect the intestinal tract of many animal species including mammals. Genetic heterogeneity of G. duodenalis is well described but the zoonotic potential is still not clear. In this study, we analysed 100 Giardia DNA samples directly isolated from human stool specimens, to get more insight in the different G. duodenalis assemblages present in the Dutch human population. Results showed that these human isolates could be divided into two main Assemblages A and B within the G. duodenalis group on the basis of PCR assays specific for the Assemblages A and B and the DNA sequences of 18S ribosomal RNA and the glutamate dehydrogenase (gdh) genes. Genotyping results showed that G. duodenalis isolates originating from Dutch human patients belonged in 35% of the cases to Assemblage A (34/98) and in 65% of the cases to Assemblage B (64/98) whereas two human cases remained negative in all assays tested. In addition, we compared these human samples with animal samples from the Netherlands and human and animal samples from other countries. A phylogenetic analysis was carried out on the DNA sequences obtained from these Giardia and those available in GenBank. Using gdh DNA sequence analysis, human and animal Assemblage A and B Giardia isolates could be identified. However, phylogenetic analysis revealed different sub-clustering for human and animal isolates where host-species-specific assemblages (C, D, E, F and G) could be identified. The geographic origin of the human and animal samples was not a discriminating factor

Knowledge-Level Reflection

This paper presents an overview of the REFLECT project. It defines the notion of knowledge level reflection that has been central to the project, it compares this notion with existing approaches to reflection in related fields, and investigates some of the consequences of the concept of knowledge level reflection: what is a general architecture for knowledge level reflection, how to model the object component in such an architecture, what is the nature of reflective theories, how can we design such architectures, and what are the results of our actual experiments with such systems

Multipartite entangled coherent states

We propose a scheme for generating multipartite entangled coherent states via entanglement swapping, with an example of a physical realization in ion traps. Bipartite entanglement of these multipartite states is quantified by the concurrence. We also use the $N$--tangle to compute multipartite entanglement for certain systems. Finally we establish that these results for entanglement can be applied to more general multipartite entangled nonorthogonal states.Comment: 7 pages, two figures. We added more detail discussions on the generation of multipartite entangled coherent states and multipartite entangelemen

Nonclassical Fields and the Nonlinear Interferometer

We demonstrate several new results for the nonlinear interferometer, which emerge from a formalism which describes in an elegant way the output field of the nonlinear interferometer as two-mode entangled coherent states. We clarify the relationship between squeezing and entangled coherent states, since a weak nonlinear evolution produces a squeezed output, while a strong nonlinear evolution produces a two-mode, two-state entangled coherent state. In between these two extremes exist superpositions of two-mode coherent states manifesting varying degrees of entanglement for arbitrary values of the nonlinearity. The cardinality of the basis set of the entangled coherent states is finite when the ratio $\chi / \pi$ is rational, where $\chi$ is the nonlinear strength. We also show that entangled coherent states can be produced from product coherent states via a nonlinear medium without the need for the interferometric configuration. This provides an important experimental simplification in the process of creating entangled coherent states.Comment: 21 pages, 2 figure

Quantum nonlocality and applications in quantum-information processing of hybrid entangled states

The hybrid entangled states generated, e.g., in a trapped-ion or atom-cavity system, have exactly one ebit of entanglement, but are not maximally entangled. We demonstrate this by showing that they violate, but in general do not maximally violate, Bell's inequality due to Clauser, Horne, Shimony and Holt. These states are interesting in that they exhibit the entanglement between two distinct degrees of freedom (one is discrete and another is continuous). We then demonstrate these entangled states as a valuable resource in quantum information processing including quantum teleportation, entanglement swapping and quantum computation with "parity qubits". Our work establishes an interesting link between quantum information protocols of discrete and continuous variables.Comment: 5 pages, no figur