46 research outputs found

    Constructing populations in biobanking

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    This article poses the question of whether biobanking practices and standards are giving rise to the construction of populations from which various biobanking initiatives increasingly draw on for legitimacy? We argue that although recent biobanking policies encourage various forms of engagement with publics to ensure legitimacy, different biobanks conceptualize their engagement strategies very differently. We suggest that biobanks undertake a broad range of different strategies with regard to engagement. We argue that these different approaches to engagement strategies are contributing to the construction of populations, whereby specific nationalities, communities, societies, patient groups and political systems become imbued or bio-objectified with particular characteristics, such as compliant, distant, positive, commercialized or authoritarian. This bio-objectification process is problematic in relation to policy aspirations ascribed to biobanking engagement since it gives rise to reified notions of different populations.Peer reviewe

    The effect of heat treatments and homogenisation of cows' milk on gastrointestinal symptoms, inflammation markers and postprandial lipid metabolism

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    Dairy products are often reported as a source of stomach discomfort, and processing of cows' milk has been claimed to be one reason for this. To investigate the role of milk processing on adverse gastrointestinal symptoms, a cross-over, double blind clinical trial with fourteen milk sensitive subjects was set up. Pasteurised, pasteurised and homogenised, and ultra-high temperature-treated and homogenised milk, representing products from the mildest and hardest processing, were used as study meals. The amount, severity or duration of the reported symptoms or postprandial lipaemia did not differ, while significant differences were seen in the postprandial fatty acid composition of plasma between the milk types. The 92 inflammation markers measured in plasma did not differ between the subjects who consumed different types of milk. The results of the present study do not support the hypothesis that cows' milk processing could induce gastrointestinal symptoms in milk sensitive but lactose tolerant subjects. (C) 2018 Elsevier Ltd. All rights reserved

    Effect of homogenised and pasteurised versus native cows' milk on gastrointestinal symptoms, intestinal pressure and postprandial lipid metabolism

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    Some people experience gastrointestinal symptoms related to cow's milk consumption even if neither lactose intolerance nor cow's milk allergy can be diagnosed. To investigate whether milk homogenization could cause gastrointestinal problems, homogenized and pasteurized milk and native milk were served to eleven volunteers who reported such sensitivity in a random order together with an ingestible pressure measuring capsule. Postprandial lipemia did not differ between the two milk types, but significant differences were found in the postprandial plasma fatty acid composition. No significant difference was found in the amount of gastrointestinal symptoms or in the intestinal pressure after the consumption of native and processed milk. However, the obtained results on pressure in the large intestine (P = 0.068) as well as reported symptoms (P = 0.103) suggest that further studies in this area are needed with a bigger subject group and with longer exposure times to differently processed milk types. (C) 2017 Elsevier Ltd. All rights reserved

    Consent for Use of Clinical Leftover Biosample: A Survey among Chinese Patients and the General Public

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    Background: Storage of leftover biosamples generates rich biobanks for future studies, saving time and money and limiting physical impact to sample donors. Objective: To investigate the attitudes of Chinese patients and the general public on providing consent for storage and use of leftover biosamples. Design, Setting and Participants: Cross-sectional surveys were conducted among randomly selected patients admitted to a Shanghai city hospital (n = 648) and members of the general public (n = 492) from May 2010 to July 2010. Main Outcome Measures: Face-to-face interviews collected respondents-report of their willingness to donate residual biosample, trust in medical institutions, motivation for donation, concerns of donated sample use, expectations for research results return, and so on. Results: The response rate was 83.0%. Of the respondents, 89.1 % stated that they completely understood or understood most of questions. Willingness to donate residual sample was stated by 64.7%, of which 16.7 % desired the option to withdraw their donations anytime afterwards. Only 42.3 % of respondents stated they ‘‘trust’ ’ or ‘‘strongly trust’ ’ medical institutions, the attitude of trusting or strongly trusting medical institutions were significantly associated with willingness to donate in the general public group.(p,0.05) The overall assent rate for future research without specific consents was als
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