244 research outputs found
Evidence of Odderon-exchange from scaling properties of elastic scattering at TeV energies
We study the scaling properties of the differential cross section of elastic
proton-proton () and proton-antiproton () collisions at high
energies. We introduce a new scaling function, that scales -- within the
experimental errors -- all the ISR data on elastic scattering from
to GeV to the same universal curve. We explore the
scaling properties of the differential cross-sections of the elastic and
collisions in a limited TeV energy range. Rescaling the TOTEM
data from TeV to and TeV, and comparing it to D0
data at TeV, our results provide an evidence for a -channel
Odderon exchange at TeV energies, with a significance of at least 6.26.
We complete this work with a model-dependent evaluation of the domain of
validity of the new scaling and its violations. We find that the scaling
is valid, model dependently, within GeV TeV,
with a range gradually narrowing with decreasing colliding energies.Comment: Accepted in EPJ C, with typos fixed, reorganized institutions
updated, Appendix A, B, C, D, E added, 60 pages, 29 figures, 13 tables,
Odderon significance: 6.26 sigma, conclusions unchange
Proton Holography -- Discovering Odderon from Scaling Properties of Elastic Scattering
We investigate the scaling properties of elastic scattering data at ISR and
LHC energies and find that the significance of an Odderon observation is larger
than the discovery threshold of 5. As an unexpected by-product of these
investigations, for certain experimentally relevant cases, we also conjecture
the possibility of proton holography with the help of elastic proton-proton
scattering.Comment: 10 pages in one-column (better readable) form, 2 figures, invited
theory talk of T. Csorgo at the ISMD 2019 conference in Santa Fe, NM, USA,
final version, to appear in EPJ Web of Conferences (in two-column format
Production Technology and Competitiveness In the Hungarian Manufacturing Industry
Following the big transformations of the 1990s, enterprise structure and technological level seem to
have become stabilised in Hungary. Under these circumstances it is especially interesting to identify
the elements responsible for competitiveness in general, and the role technology plays in development
in particular, according to managers experienced in production and marketing. This empirical
study â based on in-depth interviews and field research â summarises characteristics of the technological
level in the sectors examined, role of technology and labour in production, effects of foreign
direct investment, relations between competition and firm-level factors determining competitiveness,
and concludes by summing up those most frequently mentioned proposals that should be incorporated
into economic policy according to managers. Main findings indicate that more qualified,
more intensive and cheaper labour can be substituted for high technology. The competitiveness of an
enterprise is not determined by technology alone, but rather by a combination of technology, the parameters
of available labour and the costs of investment increasing productivity. The insufficiency
of inter-company relations, together with a shortage of available assets necessary for investment
constitute the major threat undermining the competitiveness of enterprises in present-day Hungary
Catches of Euxoa tritici in pheromone traps for Anarsia lineatella are due to the presence of (Z)-5-decenyl acetate as an impurity
Traps baited with the synthetic pheromone of Anarsia lineatella Zeller (Lepidoptera: Gelechiidae) frequently captured also Euxoa tritici L. males (Lepidoptera: Noctuidae) in field tests in Hungary. As (E)-monounsaturated compounds are uncommon among sex attractants or pheromone components of Noctuidae, it was hypothesized that the Euxoa catches may have been due to impurities of the (Z) isomer in synthetic (E)-5-decenyl acetate, which is the major component in the pheromone lure of A. lineatella. Traps baited with synthetic (Z)-5-decenyl acetate captured large numbers of E. tritici, and the compound showed a clear doseâresponse effect. Reanalysis of the synthetic batch of (E)-5-decenyl acetate used in preparation of the A. lineatella lure showed the presence of 10% of the (Z) isomer. Traps baited with synthetic (Z)-5-decenyl acetate can be used in the future for detection and monitoring purposes of E. tritici, a widely distributed pest of cereals and other field crops. The compound also showed attraction of Euxoa seliginis Duponche
Laboratory leaching tests to investigate mobilisation and recovery of metals from geothermal reservoirs
The H2020 project âCombined Heat, Power and Metal extractionâ (CHPM2030) aims at developing a novel technology which combines geothermal energy utilisation with the extraction of metals in a single interlinked process. In order to improve the economics of geothermal-based energy production, the project investigates possible technologies for the exploitation of metal-bearing geological formations with geothermal potential at depths of 3â4âkm or deeper. In this way, the coproduction of energy and metals would be possible and could be optimized according to market demands in the future. This technology could allow the mining of deep ore bodies, particularly for critical metals, alongside power production, while minimizing environmental impact and costs. In this paper, we describe laboratory leaching experiments aimed at quantifying the relative rates and magnitudes of metal release and seeing how these vary with different fluids. Specific size fractions (250â500âÎŒm) of ground mineralised rock samples were investigated under various pressures and temperatures up to 250âbar and 250°C. Initial experiments involved testing a variety of potential leaching fluids with various mineralised samples for a relatively long time (up to 720âh) in batch reactors in order to assess leaching effectiveness. Selected fluids were used in a flow-through reactor with shorter contact time (0.6âh). To ensure possible application in a real geothermal reservoir, a range of fluids were considered, from dilute mineral acid to relatively environmentally benign fluids, such as deionised water and acetic acid. The main findings of the study include fast reaction time, meaning that steady-state fluid compositions were reached in the first few hours of reaction and enhanced mobilisation of Ca, Cd, Mn, Pb, S, Si, and Zn. Some critical elements, such as Co, Sr, and W, were also found in notable concentrations during fluid-rock interactions. However, the amount of these useful elements released is much less compared to the common elements found, which include Al, Ca, Fe, K, Mg, Mn, Na, Pb, S, Si, and Zn. Even though concentrations of dissolved metals increased during the tests, some remained low, and this may present technical challenges for metal extraction. Future efforts will work toward attaining actual fluids from depth to more tightly constrain the effect of parameters such as salinity, which will also influence metal solubility
Chronic hyperglycemia induces trans-differentiation of human pancreatic stellate cells and enhances the malignant molecular communication with human pancreatic cancer cells
BACKGROUND:
Diabetes mellitus is linked to pancreatic cancer. We hypothesized a role for pancreatic stellate cells (PSC) in the hyperglycemia induced deterioration of pancreatic cancer and therefore studied two human cell lines (RLT-PSC, T3M4) in hyperglycemic environment.
METHODOLOGY/PRINCIPAL FINDINGS:
The effect of chronic hyperglycemia (CHG) on PSCs was studied using mRNA expression array with real-time PCR validation and bioinformatic pathway analysis, and confirmatory protein studies. The stress fiber formation (IC: αSMA) indicated that PSCs tend to transdifferentiate to a myofibroblast-like state after exposure to CHG. The phosphorylation of p38 and ERK1/2 was increased with a consecutive upregulation of CDC25, SP1, cFOS and p21, and with downregulation of PPARÎł after PSCs were exposed to chronic hyperglycemia. CXCL12 levels increased significantly in PSC supernatant after CHG exposure independently from TGF-ÎČ1 treatment (3.09-fold with a 2.73-fold without TGF-ÎČ1, p<0.05). The upregualtion of the SP1 transcription factor in PSCs after CHG exposure may be implicated in the increased CXCL12 and IGFBP2 production. In cancer cells, hyperglycemia induced an increased expression of CXCR4, a CXCL12 receptor that was also induced by PSC's conditioned medium. The receptor-ligand interaction increased the phosphorylation of ERK1/2 and p38 resulting in activation of MAP kinase pathway, one of the most powerful stimuli for cell proliferation. Certainly, conditioned medium of PSC increased pancreatic cancer cell proliferation and this effect could be partially inhibited by a CXCR4 inhibitor. As the PSC conditioned medium (normal glucose concentration) increased the ERK1/2 and p38 phosphorylation, we concluded that PSCs produce other factor(s) that influence(s) pancreatic cancer behaviour.
CONCLUSIONS:
Hyperglycemia induces increased CXCL12 production by the PSCs, and its receptor, CXCR4 on cancer cells. The ligand-receptor interaction activates MAP kinase signaling that causes increased cancer cell proliferation and migration
Odderon Exchange from Elastic Scattering Differences between pp and pp Data at 1.96 TeV and from pp Forward Scattering Measurements
We describe an analysis comparing the pÂŻp elastic cross section as measured by the D0 Collaboration at a center-of-mass energy of 1.96 TeV to that in pp collisions as measured by the TOTEM Collaboration at 2.76, 7, 8, and 13 TeV using a model-independent approach. The TOTEM crosssections, extrapolated to a center-of-mass energy of âs=1.96ââTeV, are compared with the D0 measurement in the region of the diffractive minimum and the second maximum of the pp cross section. The two data sets disagree at the 3.4Ï level and thus provide evidence for the t-channel exchange of a colorless, C-odd gluonic compound, also known as the odderon. We combine these results with a TOTEM analysis of the same C-odd exchange based on the total cross section and the ratio of the real to imaginary parts of the forward elastic strong interaction scatteringamplitude in pp scattering for which the significance is between 3.4Ï and 4.6Ï. The combined significance is larger than 5Ï and is interpreted as the first observation of the exchange of a colorless, C-odd gluonic compound
- âŠ