Electromagnetic Simulation and Design of a Novel Waveguide RF Wien Filter for Electric Dipole Moment Measurements of Protons and Deuterons

The conventional Wien filter is a device with orthogonal static magnetic and electric fields, often used for velocity separation of charged particles. Here we describe the electromagnetic design calculations for a novel waveguide RF Wien filter that will be employed to solely manipulate the spins of protons or deuterons at frequencies of about 0.1 to 2 MHz at the COoler SYnchrotron COSY at J\"ulich. The device will be used in a future experiment that aims at measuring the proton and deuteron electric dipole moments, which are expected to be very small. Their determination, however, would have a huge impact on our understanding of the universe.Comment: 10 pages, 10 figures, 4 table

Polarizing a stored proton beam by spin flip?

We discuss polarizing a proton beam in a storage ring, either by selective removal or by spin flip of the stored ions. Prompted by recent, conflicting calculations, we have carried out a measurement of the spin flip cross section in low-energy electron-proton scattering. The experiment uses the cooling electron beam at COSY as an electron target. The measured cross sections are too small for making spin flip a viable tool in polarizing a stored beam. This invalidates a recent proposal to use co-moving polarized positrons to polarize a stored antiproton beam.Comment: 18 pages, 6 figure

Measurement of the Spin-Dependence of the pbar-p Interaction at the AD-Ring

We propose to use an internal polarized hydrogen storage cell gas target in the AD ring to determine for the first time the two total spin-dependent pbar-p cross sections sigma_1 and sigma_2 at antiproton beam energies in the range from 50 to 450 MeV. The data obtained are of interest by themselves for the general theory of pbar-p interactions since they will provide a first experimental constraint of the spin-spin dependence of the nucleon-antinucleon potential in the energy range of interest. In addition, measurements of the polarization buildup of stored antiprotons are required to define the optimum parameters of a future, dedicated Antiproton Polarizer Ring (APR), intended to feed a double-polarized asymmetric pbar-p collider with polarized antiprotons. Such a machine has recently been proposed by the PAX collaboration for the new Facility for Antiproton and Ion Research (FAIR) at GSI in Darmstadt, Germany. The availability of an intense stored beam of polarized antiprotons will provide access to a wealth of single- and double-spin observables, thereby opening a new window on QCD spin physics.Comment: 51 pages, 23 figures, proposal submitted to the SPS committee of CER

Vitamin D in incident nephrotic syndrome: a Midwest Pediatric Nephrology Consortium study

Cross-sectional studies of children with prevalent nephrotic syndrome (NS) have shown 25-vitamin D (25(OH)D) deficiency rates of 20–100 %. Information on 25(OH)D status in incident patients or following remission is limited. This study aimed to assess 25(OH)D status of incident idiopathic NS children at presentation and longitudinally with short-term observation

ELETROOXIDAÇÃO NO TRATAMENTO DE EFLUENTES DE LAVANDERIA HOSPITALAR

No presente estudo foram realizados ensaios de tratamento utilizando os processos oxidativos avançados (POA’s) visando a mineralização e a detoxificação dos efluentes gerados em uma lavanderia hospitalar. Os ensaios envolveram a utilização do processo de eletrooxidação. Foram realizadas análises dos parâmetros globais e análises toxicológicas, antes e após cada ensaio. Desta forma buscou-se avaliar a eficiência dos métodos empregados na redução dos parâmetros globais, e na detoxificação dos efluentes da lavanderia hospitalar em questão. Os ensaios envolvendo o processo de eletrooxidação com condutividade induzida através da adição de NaCl realizados durante 60 minutos obtiveram os melhores desempenhos. O efluente gerado no enxágüe inicial das compressas passou da condição de extremamente tóxico (12,58%) para moderadamente tóxico (61,59%), enquanto que as reduções de DBO5 e DQO foram de respectivamente, 32% e 9%. Com relação ao efluente oriundo da etapa da lavagem, a DQO apresentou uma redução de 41%, enquanto que a toxicidade foi reduzida consideravelmente, passando da condição de extremamente tóxico (6,89%) para pouco tóxico (76,65%

Design and test of a NbTi prototype coil for a low beta section

The design of superconducting quadrupoles for a proton and antiproton low beta section and the test of a prototype coil are presented. Previous studies [1,2] show that high gradient and short quadrupole magnets are required for a compact low beta section in order to allow the insertion of such a magnetic system with minor changes of the lattice [3]; each quadrupole is 400 mm long and has to provide a magnetic induction gradient of 60 T/m. A beam pipe of at least 120 mm diameter is required to avoid beam loss during injection and before the beam cooling. The magnetic design of the superconducting magnets for the low beta section is presented, together with a detailed discussion of the quench protection design. Two prototype coils were produced and one of them was tested. A detailed description of the test setup and a full discussion of the results will be presented

Recurrence of nephrotic syndrome following kidney transplantation is associated with initial native kidney biopsy findings

Background and objectives: Steroid-resistant nephrotic syndrome (SRNS) due to focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD) is a leading cause of end-stage kidney disease in children. Recurrence of primary disease following transplantation is a major cause of allograft loss. The clinical determinants of disease recurrence are not completely known. Our objectives were to determine risk factors for recurrence of FSGS/MCD following kidney transplantation and factors that predict response to immunosuppression following recurrence. Methods: Multicenter study of pediatric patients with kidney transplants performed for ESKD due to SRNS between 1/2006 and 12/2015. Demographics, clinical course, and biopsy data were collected. Patients with primary-SRNS (PSRNS) were defined as those initially resistant to corticosteroid therapy at diagnosis, and patients with late-SRNS (LSRNS) as those initially responsive to steroids who subsequently developed steroid resistance. We performed logistic regression to determine risk factors associated with nephrotic syndrome (NS) recurrence. Results: We analyzed 158 patients; 64 (41%) had recurrence of NS in their renal allograft. Disease recurrence occurred in 78% of patients with LSRNS compared to 39% of those with PSRNS. Patients with MCD on initial native kidney biopsy had a 76% recurrence rate compared with a 40% recurrence rate in those with FSGS. Multivariable analysis showed that MCD histology (OR; 95% CI 5.6; 1.3–23.7) compared to FSGS predicted disease recurrence. Conclusions: Pediatric patients with MCD and LSRNS are at higher risk of disease recurrence following kidney transplantation. These findings may be useful for designing studies to test strategies for preventing recurrence