Minimizing the Cost and Enhancing the Security for Cloud Hosting Service

Cloud computing is a new emerging technology which provides different kinds of services through internet and reduces maintenance cost as well as provides data reliability. Now a days many cloud service providers are providing services with different policies and prices. But it leads difficult to customers to choose cloud services with less price. That clients as a rule put their information into a single cloud and after that just trust to luckiness. Proposing new data hosting technique termed as CHARM which supports two strong functionalities.The first is selecting a few suitable clouds and a fitting excess system to store information with minimized financial expense and ensured accessibility.The second is setting off a move procedure to re-disperse information as indicated by the varieties of information access example and evaluating of clouds.In this project defining secret sharing algorithm to reduce the risk of data intrusion and the loss of service availability in the cloud and ensure data integrity. Finally proposed scheme not only saves the cost and also Maintains data and price adjustments

Classroom enrichment through children's specialties.

Thesis (Ed.M.)--Boston Universit

Neurocognition and Disability in Patients with Schizophrenia compared with Healthy Controls

BACKGROUND: Majority of patients with schizophrenia have life-long disability in their social and occupational functioning. Cognitive impairment is recognized as an important domain of schizophrenia, with a wide range of deficits seen among patients with schizophrenia. AIM OF THE STUDY: The current study aimed at assessing the neurocognitive function in clinically stable schizophrenia patients, in comparison with age and gender matched controls. Secondary aim was to assess any correlation between neurocognitive deficits and duration of illness; neurocognitive deficits and disability among patients with schizophrenia. METHODOLOGY: 20 clinically stable schizophrenics & 20 age and gender matched healthy controls were included in the study. Select 8 tests from the NIMHANS Neuropsychological battery was used to assess the neurocognitive functions such as attention, processing speed, verbal learning and memory, executive functions, visual memory and visuospatial skills. RESULTS: Results revealed a statistically significant difference between the two groups in the performance of all neurocognitive tests, with the schizophrenia patients group scoring lesser. Within the patient group, those with duration of illness < 2 years scored more on tasks for attention, verbal learning and memory and visual memory & had lower degree of disability, which were statistically significant. CONCLUSION: The current study emphasizes on the importance of assessing neurocognitive functions in all schizophrenia patients. Recently, cognitive remediation therapy is being done to improve the neurocognitive functioning which can have a significant implication on the overall well-being of the patient

IMPACT TESTING OF 18 ADULT MOUTHGUARDS

Mouthguards are used by sports participants to reduce dental injuries, but there is limited evidence of effectiveness of mouthguards. This research compared biomechanical impact performance data from 18 adult mouthguards available in New Zealand. Repeated impact testing was conducted on the centre of each mouthguard mounted on a dental model. The best mouthguards when impact absorption scores were considered were Avaro International, Shock Doctor Power Hilo v4.5 (upper/lower), and Signature Proplus Gel Type 3; The worst mouthguards were Shock Tec Classic and Professional moulded 1 senior custom laminated. Our impact results seem in contrast to other studies which support the belief that custom mouthguards provide superior protection against injury than boil-and-bite mouthguards (which are all usually EVA low stiffness)

Applying ecological systems theory to juvenile legal system interventions outcomes research: a measurement framework

Intervention research and development for youth in the juvenile legal system (JLS) has often focused on recidivism as the primary outcome of interest. Although recidivism is an important outcome, it is ultimately a downstream marker of success and is affected by changes in other domains of youths’ lives (e.g., family and peer relations, neighborhood safety, local and state-level policies). Thus, the present manuscript proposes the application of ecological systems theory to selecting outcomes to assess intervention effects in JLS intervention research to better capture proximal and distal influences on youth behavior. To that end, we first provide an overview of the strengths and limitations of using recidivism as an outcome measure. Next, the current application of social ecology theory to existing research on both risk and protective factors of JLS involvement is discussed, as well as existing work on assessing social-ecological domains within intervention studies. Then, a measurement framework is introduced for selecting pertinent domains of youths’ social ecologies to assess as intervention outcomes, moderators, and mediators. To facilitate this, we provide examples of concrete constructs and measures that researchers may select. We conclude with potential new avenues of research to which our proposed framework could lead, as well as potential limitations of implementing our framework

Graphic Warning Labels Elicit Affective and Thoughtful Responses from Smokers: Results of a Randomized Clinical Trial

Objective Observational research suggests that placing graphic images on cigarette warning labels can reduce smoking rates, but field studies lack experimental control. Our primary objective was to determine the psychological processes set in motion by naturalistic exposure to graphic vs. text-only warnings in a randomized clinical trial involving exposure to modified cigarette packs over a 4-week period. Theories of graphic-warning impact were tested by examining affect toward smoking, credibility of warning information, risk perceptions, quit intentions, warning label memory, and smoking risk knowledge. Methods Adults who smoked between 5 and 40 cigarettes daily (N = 293; mean age = 33.7), did not have a contra-indicated medical condition, and did not intend to quit were recruited from Philadelphia, PA and Columbus, OH. Smokers were randomly assigned to receive their own brand of cigarettes for four weeks in one of three warning conditions: text only, graphic images plus text, or graphic images with elaborated text. Results Data from 244 participants who completed the trial were analyzed in structural-equation models. The presence of graphic images (compared to text-only) caused more negative affect toward smoking, a process that indirectly influenced risk perceptions and quit intentions (e.g., image-\u3enegative affect-\u3erisk perception-\u3equit intention). Negative affect from graphic images also enhanced warning credibility including through increased scrutiny of the warnings, a process that also indirectly affected risk perceptions and quit intentions (e.g., image-\u3enegative affect-\u3erisk scrutiny-\u3ewarning credibility-\u3erisk perception-\u3equit intention). Unexpectedly, elaborated text reduced warning credibility. Finally, graphic warnings increased warning-information recall and indirectly increased smoking-risk knowledge at the end of the trial and one month later. Conclusions In the first naturalistic clinical trial conducted, graphic warning labels are more effective than text-only warnings in encouraging smokers to consider quitting and in educating them about smoking’s risks. Negative affective reactions to smoking, thinking about risks, and perceptions of credibility are mediators of their impact

CCL2 nitration is a negative regulator of chemokine-mediated inflammation.

Chemokines promote leukocyte recruitment during inflammation. The oxidative burst is an important effector mechanism, this leads to the generation of reactive nitrogen species (RNS), including peroxynitrite (ONOO). The current study was performed to determine the potential for nitration to alter the chemical and biological properties of the prototypical CC chemokine, CCL2. Immunofluorescence was performed to assess the presence of RNS in kidney biopsies. Co-localisation was observed between RNS-modified tyrosine residues and the chemokine CCL2 in diseased kidneys. Nitration reduced the potential of CCL2 to stimulate monocyte migration in diffusion gradient chemotaxis assays (p < 0.05). This was consistent with a trend towards reduced affinity of the nitrated chemokine for its cognate receptor CCR2b. The nitrated chemokine was unable to induce transendothelial monocyte migration in vitro and failed to promote leukocyte recruitment when added to murine air pouches (p < 0.05). This could potentially be attributed to reduced glycosaminoglycan binding ability, as surface plasmon resonance spectroscopy showed that nitration reduced heparan sulphate binding by CCL2. Importantly, intravenous administration of nitrated CCL2 also inhibited the normal recruitment of leukocytes to murine air pouches filled with unmodified CCL2. Together these data suggest that nitration of CCL2 during inflammation provides a mechanism to limit and resolve acute inflammation

Lesbian, gay, bisexual and transgender older people in Ireland: Mental health issues

International policy initiatives have highlighted the need to include older lesbian, gay, bisexual and transgender (LGBT) issues in the provision of appropriate health and social care. However, empirical studies in the area remain sparse. The aim of this study was to investigate the experiences and needs of LGBT people over the age of 55 years living in Ireland and this article reports on specific mental health issues. Mixed methods were used involving 144 surveys and 36 semi-structured in-depth interviews. The findings revealed that a significant number of the survey respondents had experienced a mental health problem at some point in their lives with interview participants providing further details of their concerns. It is recommended that policy makers address the mental health needs of older LGBT people in future strategic directives and develop standards of care that support the principles of equality, inclusion and respect for diversity