1,071 research outputs found
Investigation of reliability attributes and accelerated stress factors on terrestrial solar cells
Major effort during this reporting period was devoted to two tasks: improvement of the electrical measurement instrumentation through the design and construction of a microcomputer controlled short interval tester, and better understanding of second quadrant behavior by developing a mathematical model relating cell temperature to electrical characteristics. In addition, some preliminary work is reported on an investigation into color changes observed after stressing
Effect of localized holes on the long-range order in bilayer antiferromagnets
The effect of localized holes on the long-range antiferromagnetic order in
bilayer cuprates is studied, by applying the renormalization group to the
appropriate non-linear sigma model. The theory accounts quantitatively for the
magnetic phase diagram of Ca doepd YBa_2Cu_3O_6.Comment: 2 pages, to appear in Physica
Phase Field Theory of Heterogeneous Crystal Nucleation
A phase eld approach is developed to model wetting and heterogeneous crystal
nucleation of an undercooled pure liquid in contact with a sharp wall. We
discuss various choices for the boundary condition at the wall and determine
the properties of critical nuclei, including their free energy of formation and
the contact angle as a function of undercooling. We nd for particular choices
of boundary conditions, we may realize either an analog of the classical
spherical cap model or decidedly non-classical behavior, where the contact
angle decreases from its value taken at the melting point towards complete
wetting at a critical undercooling.Comment: 4 figure
Rocket Fin Test Fixture Development & Exploration of Rotation Inducing Fin Design
The purpose of this senior project was to develop a method of applying rotation inducing rocket fin concepts to rockets for the benefit of the University of Akron Akronauts; the student led rocket design team. The project was performed independently of the team’s current efforts as a research and development endeavor for future team projects. Main project goals were divided into three parts: design a fin test fixture for verification testing in the University’s wind tunnel, develop a parameter-driven software model that could be used to generate design options with theoretical performance data as an output, and run fluid dynamics analyses to offer additional support to findings. At a higher level, this project was chosen as an opportunity to exercise a few of the many different facets of the engineering process. Over the course of the project, our team received valuable experience with: idea generation and brainstorming, concept vetting, technical software programming, process troubleshooting, rapid prototyping, and aerodynamic-related testing
Distinguishing ecological from evolutionary approaches to transposable elements
Considerable variation exists not only in the kinds of transposable elements (TEs) occurring within the genomes of different species, but also in their abundance and distribution. Noting a similarity to the assortment of organisms among ecosystems, some researchers have called for an ecological approach to the study of transposon dynamics. However, there are several ways to adopt such an approach, and it is sometimes unclear what an ecological perspective will add to the existing co-evolutionary framework for explaining transposon-host interactions. This review aims to clarify the conceptual foundations of transposon ecology in order to evaluate its explanatory prospects. We begin by identifying three unanswered questions regarding the abundance and distribution of TEs that potentially call for an ecological explanation. We then offer an operational distinction between evolutionary and ecological approaches to these questions. By determining the amount of variance in transposon abundance and distribution that is explained by ecological and evolutionary factors, respectively, it is possible empirically to assess the prospects for each of these explanatory frameworks. To illustrate how this methodology applies to a concrete example, we analyzed whole-genome data for one set of distantly related mammals and another more closely related group of arthropods. Our expectation was that ecological factors are most informative for explaining differences among individual TE lineages, rather than TE families, and for explaining their distribution among closely related as opposed to distantly related host genomes. We found that, in these data sets, ecological factors do in fact explain most of the variation in TE abundance and distribution among TE lineages across less distantly related host organisms. Evolutionary factors were not significant at these levels. However, the explanatory roles of evolution and ecology become inverted at the level of TE families or among more distantly related genomes. Not only does this example demonstrate the utility of our distinction between ecological and evolutionary perspectives, it further suggests an appropriate explanatory domain for the burgeoning discipline of transposon ecology. The fact that ecological processes appear to be impacting TE lineages over relatively short time scales further raises the possibility that transposons might serve as useful model systems for testing more general hypotheses in ecology
Lessons from development: A role for asymmetric stem cell division in cancer
AbstractAsymmetric stem cell division has emerged as a major regulatory mechanism for physiologic control of stem cell numbers. Reinvigoration of the cancer stem cell theory suggests that tumorigenesis may be regulated by maintaining the balance between asymmetric and symmetric cell division. Therefore, mutations affecting this balance could result in aberrant expansion of stem cells. Although a number of molecules have been implicated in regulation of asymmetric stem cell division, here, we highlight known tumor suppressors with established roles in this process. While a subset of these tumor suppressors were originally defined in developmental contexts, recent investigations reveal they are also lost or mutated in human cancers. Mutations in tumor suppressors involved in asymmetric stem cell division provide mechanisms by which cancer stem cells can hyperproliferate and offer an intriguing new focus for understanding cancer biology. Our discussion of this emerging research area derives insight from a frontier area of basic science and links these discoveries to human tumorigenesis. This highlights an important new focus for understanding the mechanism underlying expansion of cancer stem cells in driving tumorigenesis
Light-curve Modulation of Low-mass Stars in K2. I. Identification of 481 Fast Rotators in the Solar Neighborhood
The K2 mission is targeting large numbers of nearby (d 40 mas yr^(−1), V < 20). Additionally, the mission is targeting low-mass, high proper motion stars associated with the local (d < 500 pc) Galactic halo population also selected from SUPERBLINK. K2 campaigns 0 through 8 monitored a total of 26,518 of these cool main-sequence stars. We used the auto-correlation function to search for fast rotators by identifying short-period photometric modulations in the K2 light curves. We identified 481 candidate fast rotators with rotation periods <4 days that show light-curve modulations consistent with starspots. Their kinematics show low average transverse velocities, suggesting that they are part of the young disk population. A subset (13) of the fast rotators is found among those targets with colors and kinematics consistent with the local Galactic halo population and may represent stars spun up by tidal interactions in close binary systems. We further demonstrate that the M dwarf fast rotators selected from the K2 light curves are significantly more likely to have UV excess and discuss the potential of the K2 mission to identify new nearby young GKM dwarfs on the basis of their fast rotation rates. Finally, we discuss the possible use of local halo stars as fiducial, non-variable sources in the Kepler fields
Emotional expression during attention-deficit/hyperactivity disorders treatment: initial assessment of treatment effects.
OBJECTIVE: The purpose of this research was to provide an initial examination of the effects of atomoxetine and stimulants on emotional expression using a newly developed scale for assessing emotional expression in children with attention-deficit/hyperactivity disorder (ADHD).
METHOD: The parent-rated Expression and Emotion Scale for Children (EESC) was collected during two studies. During a cross-sectional validation study, the EESC was completed to assess the child\u27s current treatment and retrospectively for previous medication. In a randomized, placebo-controlled trial of atomoxetine, the EESC was collected at baseline and endpoint.
RESULTS: In the validation study, no statistically significant differences in EESC scores were found between groups taking atomoxetine (n = 74) and stimulants (n = 105). Patients who switched from a stimulant to atomoxetine (n = 40) had greater improvement in emotional expression than those switched to another stimulant (n = 21) (p = 0.008). In the clinical trial, no difference in rates of worsening of emotional expression were observed (atomoxetine 8.8%, placebo 12.3%; p = 0.440).
CONCLUSION: No treatment differences in emotional expression were observed based on current medications. However, stimulant patients needing to switch medications may have greater improvements in emotional expression by switching to atomoxetine
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