565 research outputs found
Covariance-based online validation of video tracking
This paper is a postprint of a paper submitted to and accepted for publication in Electronics Letters and is subject to Institution of Engineering and Technology Copyright. The copy of record is available at IEEE Digital LibraryA novel approach is proposed for online evaluation of video tracking without ground-truth data. The temporal evolution of the covariance features is exploited to detect the stability of the tracker output over time. A model validation strategy performs such detection without learning the failure cases of the tracker under evaluation. Then, the tracker performance is estimated by a finite state machine determining whether the tracker is on-target (successful) or not (unsuccessful). The experimental results over a heterogeneous dataset show that the proposed approach outperforms related state-of-the-art approaches in terms of performance and computational cost.This work was supported by the Spanish Government (TEC2011-25995, EventVideo)
Equações para a estimativa de peso da biomassa aérea da bracatinga (Mimosa scabrella Benth.) na idade de corte.
Este trabalho foi estimulado pela escassez de instrumentos para estimar a produtividade da bracatinga na idade de corte, visando estatÃsticas locais ou regionais. Foram amostrados cinco sÃtios, nos municÃpios de Colombo e Bocaiúva do Sul - PR. Em cada sitio selecionaram-se 40 árvores para a determinação dos pesos das frações lenha, galhos, biomassa verde (folhas e ramos tenros) e da biomassa total. Os pesos reais das frações e do total de cada árvore, mais as variáveis independentes altura total e diâmetro a 1,30 m (DAP) foram introduzidos no programa STATGRAPHICS, versão 4.0, para realizar os ajustes necessários para a obtenção das equações de regressão. Três modelos demonstraram ser adequados para estimar o peso de qualquer fração e da biomassa total, sendo que a mais precisa foi Y = a.DAPb, onde Y = peso; a e b = constantes
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The effect of the GLP-1 analogue Exenatide on functional connectivity within an NTS-based network in women with and without obesity.
ObjectiveThe differential effect of GLP-1 agonist Exenatide on functional connectivity of the nucleus tractus solitaries (NTS), a key region associated with homeostasis, and on appetite-related behaviours was investigated in women with normal weight compared with women with obesity.MethodsFollowing an 8-h fast, 19 female subjects (11 lean, 8 obese) participated in a 2-d double blind crossover study. Subjects underwent functional magnetic resonance imaging at fast and 30-min post subcutaneous injection of 5 μg of Exenatide or placebo. Functional connectivity was examined with the NTS. Drug-induced functional connectivity changes within and between groups and correlations with appetite measures were examined in a region of interest approach focusing on the thalamus and hypothalamus.ResultsWomen with obesity reported less hunger after drug injection. Exenatide administration increased functional connectivity of the left NTS with the left thalamus and hypothalamus in the obese group only and increased the correlation between NTS functional connectivity and hunger scores in all subjects, but more so in the obese.ConclusionsObesity can impact the effects of Exenatide on brain connectivity, specifically in the NTS and is linked to changes in appetite control. This has implications for the use of GLP-1 analogues in therapeutic interventions
Smoke and fire dynamics in atria and large enclosures: An overview
The proliferation of atria within modern large buildings is relatively recent. An atrium can be defined as a large open space connecting two or more storeys. Atria are important architectonical features since the 60's and can be found, among others, in shopping centres, office buildings and high-rise buildings, airports, stations and sports centres. However, the atrium represents an innovative, complex and non conventional architectonical element that can lead to fire environments diverging significantly from those in conventional compartments used in the development of current codes and standards. They are a source of discussion in the fire safety community because smoke can easily spread from one floor to another making the traditional methodologies for compartmentation of little or null effect. The design of smoke management in atria has been based on prescriptive codes since the 70's. It was not until the mid 80's that the phenomena started to be the objective of both experimental and numerical studies. It is because of the subsequent improved understanding on fire dynamics and smoke management together with the increased computing power available nowadays, that there is a progressive movement from prescriptive-based to performance-based codes which is also chaning the way atria are designed. The aim of the present work is to provide a broad overview of the current state-of-the-art of fires in atria. A brief introduction to the characteristics and types of atrium structures is presented first. Then, a description of the fire dynamics as well as the main safety problems that arise in case of fire are considered. A historical discussion of the research, including experimental and numerical studies, is presented, and current design methodologies and fire safety strategies are discussed. The final part of the overview addresses the international tendencies towards the introduction of performance-based fire protection codes. This overview highlights the need for further experimental studies and validations of numerical simulations for a wider range of fire conditions. © 2010 by Nova Science Publishers, Inc. All rights reserved
Global mode analysis of axisymmetric bluff-body wakes: Stabilization by base bleed
International audienceThe flow around a slender body with a blunt trailing edge is unstable in most situations of interest. Usually the flow instabilities are generated within the wake behind the bluff body, inducing fluctuating forces and introducing the possibility of resonance mechanisms with modes of the structure. Base bleed is a simple and well-known means of stabilizing the wake. In the present research, we investigate the global instability properties of the laminar-incompressible flow that develops behind a cylinder with sharp edges and axis aligned with the free stream using a spectral domain decomposition method. In particular, we describe the flow instability characteristics as a function of the Reynolds number, Re=?W8D/µ, and the bleed coefficient, defined as the bleed-to-free-stream velocity ratio, Cb=Wb/W8, where D is the diameter of the body and ? and µ the density and viscosity of the free stream, respectively. For a truncated cylinder of aspect ratio L/D=5, where L is the length of the body, our calculations reveal the presence of a first steady bifurcation in the wake at Re?391, as well as a second oscillatory one at Re?715 with an associated Strouhal number St?0.0905 for the most unstable azimuthal mode {pipe}m{pipe}=1. In addition, we report the existence of two critical values of the bleed coefficient Cb1*(Re,{pipe}m{pipe}) and Cb2*(Re,{pipe}m{pipe}) < Cb1*, which vary with the aspect ratio of the body, needed to stabilize both the first and second bifurcations in the range of Reynolds numbers under study, 0=Re=2200. Finally, the numerical results for the oscillatory mode obtained for a bulletlike body of aspect ratio L/D=2 without base bleed are compared with experiments performed in a wind tunnel using hot-wire anemometry, showing the limitations of using an axisymmetric basic flow at Reynolds numbers higher than the critical one corresponding to the first steady bifurcation in the global stability analysis. © 2009 American Institute of Physics
Heterogeneous nature and distribution of interruptions in dinucleotides may indicate the existence of biased substitutions underlying microsatellite evolution
[Abstract] Some aspects of microsatellite evolution, such as the role of base substitutions, are far from being fully understood. To examine the significance of base substitutions underlying the evolution of microsatellites we explored the nature and the distribution of interruptions in dinucleotide repeats from the human genome. The frequencies that we inferred in the repetitive sequences were statistically different from the frequencies observed in other noncoding sequences. Additionally, we detected that the interruptions tended to be towards the ends of the microsatellites and 5′-3′ asymmetry. In all the estimates nucleotides forming the same repetitive motif seem to be affected by different base substitution rates in AC and AG. This tendency itself could generate patterning and similarity in flanking sequences and reconcile these phenomena with the high mutation rate found in flanking sequences without invoking convergent evolution. Nevertheless, our data suggest that there is a regional bias in the substitution pattern of microsatellites. The accumulation of random substitutions alone cannot explain the heterogeneity and the asymmetry of interruptions found in this study or the relative frequency of different compound microsatellites in the human genome. Therefore, we cannot rule out the possibility of a mutational bias leading to convergent or parallel evolution in flanking sequences
Loneliness Mediates the Relationship Between Early Life Stress and Perceived Stress but not Hypothalamic-Pituitary-Adrenal Axis Functioning
Many authors have proposed that early life stress (ELS) provokes a dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis and contributes negatively to the management of stress in adulthood. However, these associations have not always been observed, making it necessary to include new factors that could explain the different results found. In this regard, people with ELS experiences report less social support during adulthood, suggesting that loneliness could be a mediating factor. Thus, our aims were to investigate whether ELS was related to both perceived stress and diurnal HPA axis activity, and whether loneliness mediates these relationships, in a community sample (N=187, 18-55years old). Fourteen cortisol samples were collected on two non-consecutive days to obtain the overall diurnal cortisol, diurnal cortisol slope, and bedtime levels. Additionally, ELS was assessed with the Risky Families Questionnaire (RFQ) and the Recalled Childhood and Adolescence Perceived Stress (ReCAPS) measure. Results revealed that ELS was associated with perceived stress, but not HPA axis functioning, and loneliness mediated the relationship between ELS and perceived stress, but not between ELS and HPA axis functioning. Similar results were found for both ELS questionnaires, suggesting that the ReCAPS is an adequate tool. These results highlight the importance of loneliness in understanding the long-term effects of ELS, and they indicate different effects of ELS on subjective and physiological stress indicators
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