Non-Gaussianity in three fluid curvaton model

The generation of non-gaussianity is studied in a three fluid curvaton model. By utilizing second order perturbation theory we derive general formulae for the large scale temperature fluctuation and non-gaussianity parameter, $f_{NL}$, that includes the possibility of a non-adiabatic final state. In the adiabatic limit we recover previously known results. The results are applied to a three fluid curvaton model where the curvaton decays into radiation and matter. We find that the amount of non-gaussianity decreases as the final state of the system becomes more adiabatic and that the generated non-gaussianity in the scenario is small, $|f_{NL}| \sim \mathcal{O}(1)$.Comment: 10 pages, 2 figure

Hypersonic research engine project. Phase 2: Some combustor test results of NASA aerothermodynamic integration model

Combustor test results of the NASA Aerothermodynamic Integration Model are presented of a ramjet engine developed for operation between Mach 3 and 8. Ground-based and flight experiments which provide the data required to advance the technology of hypersonic air-breathing propulsion systems as well as to evaluate facility and testing techniques are described. The engine was tested with synthetic air at Mach 5, 6, and 7. The hydrogen fuel was heated to 1500 R prior to injection to simulate a regeneratively cooled system. Combustor efficiencies up to 95 percent at Mach 6 were achieved. Combustor process in terms of effectiveness, pressure integral factor, total pressure recovery and Crocco's pressure-area relationship are presented and discussed. Interactions between inlet-combustor, combustor stages, combustor-nozzle, and the effects of altitude, combustor step, and struts are observed and analyzed

Constraints on the three-fluid model of curvaton decay

A three fluid system describing the decay of the curvaton is studied by numerical and analytical means. We place constraints on the allowed interaction strengths between the fluids and initial curvaton density by requiring that the curvaton decays before nucleosynthesis while nucleosynthesis, radiation-matter equality and decoupling occur at correct temperatures. We find that with a continuous, time-independent interaction, a small initial curvaton density is naturally preferred along with a low reheating temperature. Allowing for a time-dependent interaction, this constraint can be relaxed. In both cases, a purely adiabatic final state can be generated, but not without fine-tuning. Unlike in the two fluid system, the time-dependent interactions are found to have a small effect on the curvature perturbation itself due to the different nature of the system. The presence of non-gaussianity in the model is discussed.Comment: 9 pages, 10 figure

Operative strategy for fistula-in-ano without division of the anal sphincter

We would like to thank Mr ER MacDonald for his contribution in data collection during the early years of the study. The material in this paper was presented as a poster at the annual meeting of the American Society of Colon and Rectal Surgeons held in Vancouver, Canada, May 2011.Peer reviewedPublisher PD

Scalar form-factor of the proton with light-cone QCD sum rules

In this article, we calculate the scalar form-factor of the proton in the framework of the light-cone QCD sum rules approach with the three valence quark light-cone distribution amplitudes up to twist-6, and observe the scalar form-factor $\sigma(t=-Q^2)$ at intermediate and large momentum transfers $Q^2> 2GeV^2$ has significant contributions from the end-point (or soft) terms. The numerical values for the $\sigma(t=-Q^2)$ are compatible with the calculations from the chiral quark model and lattice QCD at the region $Q^2>2GeV^2$.Comment: 18 pages, 7 figures, revised versio

Update on the Direct Detection of Supersymmetric Dark Matter

We compare updated predictions for the elastic scattering of supersymmetric neutralino dark matter with the improved experimental upper limit recently published by CDMS II. We take into account the possibility that the \pi-nucleon \Sigma term may be somewhat larger than was previously considered plausible, as may be supported by the masses of exotic baryons reported recently. We also incorporate the new central value of m_t, which affects indirectly constraints on the supersymmetric parameter space, for example via calculations of the relic density. Even if a large value of \Sigma is assumed, the CDMS II data currently exclude only small parts of the parameter space in the constrained MSSM (CMSSM) with universal soft supersymmetry-breaking Higgs, squark and slepton masses. None of the previously-proposed CMSSM benchmark scenarios is excluded for any value of \Sigma, and the CDMS II data do not impinge on the domains of the CMSSM parameter space favoured at the 90 % confidence level in a recent likelihood analysis. However, some models with non-universal Higgs, squark and slepton masses and neutralino masses \lappeq 700 GeV are excluded by the CDMS II data.Comment: 25 pages, 28 eps figure

The Contribution of the Light Quark Condensate to the Pion-Nucleon Sigma Term

There has been a discrepancy between values of the pion-nucleon sigma term extracted by two different methods for many years. Analysis of recent high precision pion-nucleon data has widened the gap between the two determinations. It is argued that the two extractions correspond to different quantities and that the difference between them can be understood and calculated.Comment: Modern Physics Letters A (in press

Neutrino Fluxes from CMSSM LSP Annihilations in the Sun

We evaluate the neutrino fluxes to be expected from neutralino LSP annihilations inside the Sun, within the minimal supersymmetric extension of the Standard Model with supersymmetry-breaking scalar and gaugino masses constrained to be universal at the GUT scale (the CMSSM). We find that there are large regions of typical CMSSM $(m_{1/2}, m_0)$ planes where the LSP density inside the Sun is not in equilibrium, so that the annihilation rate may be far below the capture rate. We show that neutrino fluxes are dependent on the solar model at the 20% level, and adopt the AGSS09 model of Serenelli et al. for our detailed studies. We find that there are large regions of the CMSSM $(m_{1/2}, m_0)$ planes where the capture rate is not dominated by spin-dependent LSP-proton scattering, e.g., at large $m_{1/2}$ along the CMSSM coannihilation strip. We calculate neutrino fluxes above various threshold energies for points along the coannihilation/rapid-annihilation and focus-point strips where the CMSSM yields the correct cosmological relic density for tan(beta) = 10 and 55 for $\mu$ > 0, exploring their sensitivities to uncertainties in the spin-dependent and -independent scattering matrix elements. We also present detailed neutrino spectra for four benchmark models that illustrate generic possibilities within the CMSSM. Scanning the cosmologically-favored parts of the parameter space of the CMSSM, we find that the IceCube/DeepCore detector can probe at best only parts of this parameter space, notably the focus-point region and possibly also at the low-mass tip of the coannihilation strip.Comment: 32 pages, 13 figures. v2: updated/expanded discussion of IceCube/DeepCor

Extracellular matrix-cell interactions: Focus on therapeutic applications

Extracellular matrix (ECM) macromolecules together with a multitude of different molecules residing in the extracellular space play a vital role in the regulation of cellular phenotype and behavior. This is achieved via constant reciprocal interactions between the molecules of the ECM and the cells. The ECM-cell interactions are mediated via cell surface receptors either directly or indirectly with co-operative molecules. The ECM is also under perpetual remodeling process influencing cell-signaling pathways on its part. The fragmentation of ECM macromolecules provides even further complexity for the intricate environment of the cells. However, as long as the interactions between the ECM and the cells are in balance, the health of the body is retained. Alternatively, any dysregulation in these interactions can lead to pathological processes and finally to various diseases. Thus, therapeutic applications that are based on retaining normal ECM-cell interactions are highly rationale. Moreover, in the light of the current knowledge, also concurrent multi-targeting of the complex ECM-cell interactions is required for potent pharmacotherapies to be developed in the future