AN INDEX METHOD FOR SELECTING REPRESENTATIVE CITIES OF A TARGET MARKET

An index was developed to rank U.S. metropolitan areas according to overall similarities in their socio-economic characteristics to the U.S. average. This index is given as a solution to matching a representative city or market area to a target market as well as matching a group of cities which are similar to each other. The index shows stability in ranking these cities with different consumption data for similar products and proves to be a promising approach whenever the researcher must find a group of cities which are similar to each other and to the target market.Research Methods/ Statistical Methods,

Geometry of Discrete Quantum Computing

Conventional quantum computing entails a geometry based on the description of an n-qubit state using 2^{n} infinite precision complex numbers denoting a vector in a Hilbert space. Such numbers are in general uncomputable using any real-world resources, and, if we have the idea of physical law as some kind of computational algorithm of the universe, we would be compelled to alter our descriptions of physics to be consistent with computable numbers. Our purpose here is to examine the geometric implications of using finite fields Fp and finite complexified fields Fp^2 (based on primes p congruent to 3 mod{4}) as the basis for computations in a theory of discrete quantum computing, which would therefore become a computable theory. Because the states of a discrete n-qubit system are in principle enumerable, we are able to determine the proportions of entangled and unentangled states. In particular, we extend the Hopf fibration that defines the irreducible state space of conventional continuous n-qubit theories (which is the complex projective space CP{2^{n}-1}) to an analogous discrete geometry in which the Hopf circle for any n is found to be a discrete set of p+1 points. The tally of unit-length n-qubit states is given, and reduced via the generalized Hopf fibration to DCP{2^{n}-1}, the discrete analog of the complex projective space, which has p^{2^{n}-1} (p-1)\prod_{k=1}^{n-1} (p^{2^{k}}+1) irreducible states. Using a measure of entanglement, the purity, we explore the entanglement features of discrete quantum states and find that the n-qubit states based on the complexified field Fp^2 have p^{n} (p-1)^{n} unentangled states (the product of the tally for a single qubit) with purity 1, and they have p^{n+1}(p-1)(p+1)^{n-1} maximally entangled states with purity zero.Comment: 24 page

Modulational instability of ion-acoustic wave packets in quantum pair-ion plasmas

Amplitude modulation of quantum ion-acoustic waves (QIAWs) in a quantum electron-pair-ion plasma is studied. It is shown that the quantum coupling parameter $H$ (being the ratio of the plasmonic energy density to the Fermi energy) is ultimate responsible for the modulational stability of QIAW packets, without which the wave becomes modulational unstable. New regimes for the modulational stability (MS) and instability (MI) are obtained in terms of $H$ and the positive to negative ion density ratio $\beta$. The growth rate of MI is obtained, the maximum value of which increases with $\beta$ and decreases with $H$. The results could be important for understanding the origin of modulated QIAW packets in the environments of dense astrophysical objects, laboratory negative ion plasmas as well as for the next generation laser solid density plasma experiments.Comment: 4 pages, 2 figures (to appear in Astrophysics and Space Science

Breast carcinoma is a multifactorial disease involving FOXN3, SINA3 and NEAT through repression of GATA3 and TJP

No abstract

Microbial-Physical Synthesis of Fe and Fe3O4 Magnetic Nanoparticles Using Aspergillus niger YESM1 and Supercritical Condition of Ethanol

Magnetic Fe and Fe3O4 (magnetite) nanoparticles are successfully synthesized using Aspergillus niger YESM 1 and supercritical condition of liquids. Aspergillus niger is used for decomposition of FeSO4 and FeCl3 to FeS and Fe2O3, respectively. The produced particles are exposed to supercritical condition of ethanol for 1 hour at 300∘ C and pressure of 850 psi. The phase structure and the morphology measurements yield pure iron and major Fe3O4 spherical nanoparticles with average size of 18 and 50 nm, respectively. The crystal size amounts to 9 nm for Fe and 8 nm for Fe3O4. The magnetic properties are measured to exhibit superparamagneticand ferromagnetic-like behaviors for Fe and Fe3O4 nanoparticles, respectively. The saturation magnetization amounts to 112 and 68 emu/g for Fe and Fe3O4, respectively. The obtained results open new route for using the biophysical method for large-scale production of highly magnetic nanoparticles to be used for biomedical applications

Pharmacological Or Genetic Targeting Of Transient Receptor Potential (TRP) Channels Can Disrupt The Planarian Escape Response

In response to noxious stimuli, planarians cease their typical ciliary gliding and exhibit an oscillatory type of locomotion called scrunching. We have previously characterized the biomechanics of scrunching and shown that it is induced by specific stimuli, such as amputation, noxious heat, and extreme pH. Because these specific inducers are known to activate Transient Receptor Potential (TRP) channels in other systems, we hypothesized that TRP channels control scrunching. We found that chemicals known to activate TRPA1 (allyl isothiocyanate (AITC) and hydrogen peroxide) and TRPV (capsaicin and anandamide) in other systems induce scrunching in the planarian species Dugesia japonica and, except for anandamide, in Schmidtea mediterranea. To confirm that these responses were specific to either TRPA1 or TRPV, respectively, we tried to block scrunching using selective TRPA1 or TRPV antagonists and RNA interference (RNAi) mediated knockdown. Unexpectedly, co-treatment with a mammalian TRPA1 antagonist, HC-030031, enhanced AITC-induced scrunching by decreasing the latency time, suggesting an agonistic relationship in planarians. We further confirmed that TRPA1 in both planarian species is necessary for AITC-induced scrunching using RNAi. Conversely, while co-treatment of a mammalian TRPV antagonist, SB-366791, also enhanced capsaicin-induced reactions in D. japonica, combined knockdown of two previously identified D. japonica TRPV genes (DjTRPVa and DjTRPVb) did not inhibit capsaicin-induced scrunching. RNAi of DjTRPVa/DjTRPVb attenuated scrunching induced by the endocannabinoid and TRPV agonist, anandamide. Overall, our results show that although scrunching induction can involve different initial pathways for sensing stimuli, this behavior’s signature dynamical features are independent of the inducer, implying that scrunching is a stereotypical planarian escape behavior in response to various noxious stimuli that converge on a single downstream pathway. Understanding which aspects of nociception are conserved or not across different organisms can provide insight into the underlying regulatory mechanisms to better understand pain sensation