Concepts of death and the future life in the New Testament

Thesis (Ph.D.)--Boston University.The problem of this dissertation is to discover what the New Testament says concerning the death and future life of individual persons. It takes into account concepts of the eschatological events in relation to which these matters must be understood, but the primary focus is on the individual. The primary data for the study are drawn from the New Testament. Every statement pertaining to the subject has been isolated according to definite standards, then classified and listed under ten basic categories. A number of these statements were selected for exegetical study. As a background for this exegetical study an historical survey was made of concepts of death and the future life in the thought of first century Judaism and Hellenism. From this total study several basic concepts have emerged, derived directly from the New Testament statements, and, especially, from the exegesis. In different strands of writing these concepts received varying emphases, and were expressed differently. Nevertheless, they are found throughout the New Testament as components of its total thought concerning death and the future life. [TRUNCATED

Controlling chaos in spatially extended beam-plasma system by the continuous delayed feedback

In present paper we discuss the control of complex spatio-temporal dynamics in a {spatially extended} non-linear system (fluid model of Pierce diode) based on the concepts of controlling chaos in the systems with few degrees of freedom. A presented method is connected with stabilization of unstable homogeneous equilibrium state and the unstable spatio-temporal periodical states analogous to unstable periodic orbits of chaotic dynamics of the systems with few degrees of freedom. We show that this method is effective and allows to achieve desired regular dynamics chosen from a number of possible in the considered system.Comment: 12 pages, 12 figure

Intestinal epithelial replacement by transplantation of cultured murine and human cells into the small intestine.

Adult intestinal epithelial stem cells are a promising resource for treatment of intestinal epithelial disorders that cause intestinal failure and for intestinal tissue engineering. We developed two different animal models to study the implantation of cultured murine and human intestinal epithelial cells in the less differentiated "spheroid" state and the more differentiated "enteroid" state into the denuded small intestine of mice. Engraftment of donor cells could not be achieved while the recipient intestine remained in continuity. However, we were able to demonstrate successful implantation of murine and human epithelial cells when the graft segment was in a bypassed loop of jejunum. Implantation of donor cells occurred in a random fashion in villus and crypt areas. Engraftment was observed in 75% of recipients for murine and 36% of recipients for human cells. Engrafted spheroid cells differentiated into the full complement of intestinal epithelial cells. These findings demonstrate for the first time successful engraftment into the small bowel which is optimized in a bypassed loop surgical model

Experience With Radical Resection in The Management of Proximal Bile Duct Cancer

Multiple surgical and nonsurgical approaches have been advocated for the treatment of proximal bile duct cancer. However, survival appears longest when a resection can be performed. Fifteen patients treated at a university center were managed with an aggressive surgical approach. Resection of the tumor was performed in 13 of 15 patients (87%). Of the patients undergoing resection, major hepatic resection was performed in 8 (62%), while excision of vessels with reconstruction was performed in 5 (38%). Eleven of the 13 resected patients (85%) were discharged from the hospital. Clinical symptoms of recurrent disease occurred between 3 and 36 months after surgery in 7 patients, 6 of whom have died. Three other patients are alive at 5, 21, and 36 months without clinical evidence of recurrence. There was no correlation between the completeness of resection and the duration of disease-free survival

Probing structural relaxation in complex fluids by critical fluctuations

Complex fluids, such as polymer solutions and blends, colloids and gels, are of growing interest in fundamental and applied soft-condensed-matter science. A common feature of all such systems is the presence of a mesoscopic structural length scale intermediate between atomic and macroscopic scales. This mesoscopic structure of complex fluids is often fragile and sensitive to external perturbations. Complex fluids are frequently viscoelastic (showing a combination of viscous and elastic behaviour) with their dynamic response depending on the time and length scales. Recently, non-invasive methods to infer the rheological response of complex fluids have gained popularity through the technique of microrheology, where the diffusion of probe spheres in a viscoelastic fluid is monitored with the aid of light scattering or microscopy. Here we propose an alternative to traditional microrheology that does not require doping of probe particles in the fluid (which can sometimes drastically alter the molecular environment). Instead, our proposed method makes use of the phenomenon of "avoided crossing" between modes associated with the structural relaxation and critical fluctuations that are spontaneously generated in the system.Comment: 4 pages, 4 figure

Properties of an acid-tolerant, persistent Cheddar cheese isolate, Lacticaseibacillus paracasei GCRL163

The distinctive flavours in hard cheeses are attributed largely to the activity of nonstarter lactic acid bacteria (NSLAB) which dominate the cheese matrix during maturation after lactose is consumed. Understanding how different strains of NSLAB survive, compete, and scavenge available nutrients is fundamental to selecting strains as potential adjunct starters which may influence product traits. Three Lacticaseibacillus paracasei isolates which dominated at different stages over 63-week maturation periods of Australian Cheddar cheeses had the same molecular biotype. They shared many phenotypic traits, including salt tolerance, optimum growth temperature, growth on N-acetylglucosamine and N-acetylgalactosamine plus delayed growth on D-ribose, carbon sources likely present in cheese due to bacterial autolysis. However, strains 124 and 163 (later named GCRL163) survived longer at low pH and grew on D-tagatose and D-mannitol, differentiating this phenotype from strain 122. When cultured on growth-limiting lactose (0.2%, wt/vol) in the presence of high concentrations of L-leucine and other amino acids, GCRL163 produced, and subsequently consumed lactate, forming acetic and formic acids, and demonstrated temporal accumulation of intermediates in pyruvate metabolism in long-term cultures. Strain GCRL163 grew in Tween 80-tryptone broths, a trait not shared by all L. casei-group dairy isolates screened in this study. Including citrate in this medium stimulated growth of GCRL163 above citrate alone, suggesting cometabolism of citrate and Tween 80. Proteomic analysis of cytosolic proteins indicated that growth in Tween 80 produced a higher stress state and increased relative abundance of three cell envelope proteinases (CEPs) (including PrtP and Dumpy), amongst over 230 differentially expressed proteins

Amélioration de la connaissance des causes d'incendie de forêt et mise en place d'une base de données géoréférencées

Dans le cadre du programme Forest Focus, le Cemagref d'Aix-en-Provence a réalisé un guide technique intitulé « Amélioration de la connaissance des causes de départ de feu de forêt » et l'agence MTDA a développé le prototype d'un module de saisie et de cartographie interactive des incendies de forêt. Cet article présente la méthode d'investigation de recherche des causes de départ de feu adaptée au contexte méditerranéen français ; un encadré concerne spécifiquement le module de saisie et de cartographie interactive permettant d'alimenter une base de données géoréférencées

Developing a methodology towards sustainable PCD compact core drilling on planet Mars

ABSTRACT This paper describes a study of core drilling into basalt rock in anticipation of a Mars mission. Since the objective is to maintain a sustainable drilling mission on this distant planet, we perform a methodical study to examine parameters which influence sustainability including PCD tool-wear and drilling forces. INTRODUCTION Two gradual modes of insert-wear are experimentally measured: flank wear (VB) and cutting edge radius wear (CERW). Furthermore, relevant equations that relate wear to several factors including rock strength and process parameters are developed. The findings suggest a strong influence of rock hardness, process parameters, and tool geometry on tool-wear. Similar functional dependence is found for the generated thrust force and torque on rock hardness, rake angle, spindle speed, and drill feed. Consequently, equations are derived to model thrust force and torque as functions of these variables

Molecular phenotyping of multiple mouse strains under metabolic challenge uncovers a role for <i>Elovl2</i> in glucose-induced insulin secretion.

In type 2 diabetes (T2D), pancreatic β cells become progressively dysfunctional, leading to a decline in insulin secretion over time. In this study, we aimed to identify key genes involved in pancreatic beta cell dysfunction by analyzing multiple mouse strains in parallel under metabolic stress. Male mice from six commonly used non-diabetic mouse strains were fed a high fat or regular chow diet for three months. Pancreatic islets were extracted and phenotypic measurements were recorded at 2 days, 10 days, 30 days, and 90 days to assess diabetes progression. RNA-Seq was performed on islet tissue at each time-point and integrated with the phenotypic data in a network-based analysis. A module of co-expressed genes was selected for further investigation as it showed the strongest correlation to insulin secretion and oral glucose tolerance phenotypes. One of the predicted network hub genes was &lt;i&gt;Elovl2&lt;/i&gt; , encoding Elongase of very long chain fatty acids 2. &lt;i&gt;Elovl2&lt;/i&gt; silencing decreased glucose-stimulated insulin secretion in mouse and human β cell lines. Our results suggest a role for &lt;i&gt;Elovl2&lt;/i&gt; in ensuring normal insulin secretory responses to glucose. Moreover, the large comprehensive dataset and integrative network-based approach provides a new resource to dissect the molecular etiology of β cell failure under metabolic stress