25 research outputs found
Place de lâAndrocurÂź dans le traitement de lâalopĂ©cie fĂ©minine diffuse
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S1 guideline for diagnostic evaluation in androgenetic alopecia in men, women and adolescents
Ătude randomisĂ©e en double aveugle contre placebo Ă©valuant lâefficacitĂ© du mĂ©thotrexate seul ou associĂ© Ă une faible corticothĂ©rapie gĂ©nĂ©rale dans les formes sĂ©vĂšres de pelade (totales/universelles) dâĂ©volution chronique
Clobetasol propionate shampoo 0.05% and calcipotriol solution 0.005%: a randomized comparison of efficacy and safety in subjects with scalp psoriasis
Background: Scalp involvement in psoriatic patients represents a common issue. Treatment of the hairy skin requires adequate pharmaceutical formulations; hence, a new specific shampoo formulation of clobetasol propionate 0.05% was developed by Galderma R&D, Inc. Methods: For this multicenter, randomized, investigator-masked, parallel group study, 151 subjects with moderate to severe scalp psoriasis were randomized to 4 weeks of treatment with clobetasol propionate shampoo or calcipotriol solution. Results: Clobetasol propionate demonstrated significantly superior efficacy to calcipotriol solution (total severity score: mean difference 0.51, 95% CI 0.05-0.97, p=0.028; global severity score: mean difference 0.43, 95% CI 0.08-0.78, p=0.016). Adverse events were more common in the calcipotriol group than in the clobetasol propionate shampoo group. Telangiectasia and skin atrophy did not differ significantly between treatments; however, a burning sensation was significantly more common in the calcipotriol solution group. Conclusions: Short contact therapy of scalp psoriasis with this new shampoo formulation of clobetasol propionate was significantly more effective and better tolerated than calcipotriol solution for the treatment of scalp psoriasis
DĂ©tection folliculaire du titane au cours de lâalopĂ©cie frontale fibrosante (AFF) et du lichen plan pilaire (LPP) par imagerie de nano-fluorescence X
A single typical trichoscopic feature is predictive of tinea capitis: a prospective multicentre study
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Study of gene expression alteration in male androgenetic alopecia: evidence of predominant molecular signaling pathways
International audienceMale androgenetic alopecia (AGA) is the most common form of hair loss in men. It is characterized by a distinct pattern of progressive hair loss starting from the frontal area and the vertex of the scalp. Although several genetic risk loci have been identified, relevant genes for AGA remain to be defined