1,004 research outputs found

    Comparative Analysis Between Banking and Insurance Sector on Perception of Transformational Leadership Styles

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    Purpose: The purpose of this study is to examine the differences in leadership styles prevalent in the public sector with those working in the banking and insurance industries. Cluster variables from both industries included in the analysis are as follows: Idealized influence, inspiring motivation, intellectual stimulation, and individualized consideration are all components of leadership.   Theoretical Framework: Due to its apparent efficacy, transformational leadership has received a lot of attention from public sector researchers over the past decade. Successful leaders alter their teams by enlisting their followers' help in effecting change. A transformational leader is one who "transforms" their followers by inspiring them to make positive personal and professional shifts.   Design / Methodology / Approach:The study is exploratory research design using Quantitative data collected from the Banking and Insurance sector employees. The study uses a well-structured questionnaire using Likert scale items. The sample was chosen on Convenience basis from 5 select public sector Insurance companies and 5 select public sector Insurance companies. 100 Questionnaires each were distributed and 97 valid responses were selected for banking industry and 90 responses from Insurance Industry were selected for the study. Paired t test using SPSS software was utilised for analysing the data in the study.   Findings:The findings of the study show that there is significant difference between the leadership styles practices in Banking and Insurance industry. The banking sector employees showed a greater inclination towards transformational leadership with higher mean scores and statistically significant outcomes.   Research Implications: Banking and insurance each have their own distinct cultures and management philosophies; as a result, they cannot be studied as a single entity under the umbrella of the BFSI sector. Additional research on the various leadership styles currently in use within the banking and insurance sectors is necessary.   Originality/Value: There are no studies related comparative analysis between Insurance and Banking industry on the leadership styles in Public sector

    Occupational exposure to unburnt bidi tobacco elevates mutagenic burden among tobacco processors

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    The nature of mutagenic burden due to occupational exposure to tobacco flakes and dust was determined among 20 female tobacco processors (TP) and 20 matched controls (C) by testing urinary mutagenicity in the Ames assay. In addition, urinary cotinine mutagenicity in the Ames assay. In addition, urinary continine was estimated as a marker of tobacco absorption. Workers and controls were sub-divided into those with no tobacco habit (NH) and those habituated to use of masheri (a pyrolysed form of tobacco) as a dentifrice (MH). Cotinine was not detected in samples from C-NH while the mean urinary cotinine levels in TP-NH and TP-MH were significantly higer than that in C-MH (3.46 ± 0.95 and 3.57 ± 0.46 versus 1.80 ± 0.58 mM/M creatinine; P < 0.02). The majority of the urine samples from C-NH were non-mutagenic in the presence or absence of rat liver S9 while those from C-MH were mutagenic to TA98,TA100 and TA102 strains upon metabolic activation. On the other hand, direct mutagenicity to TA98, TA100 and TA102 strains respectively was noted in 6/10, 5/10 and 8/10 samples from TP-NH and 7/10, 4/10, and 3/10 samples from TP-MH. Generally, ß-glucuronidase treatment reduced or abolished the mutagenic potential of workers' urine samples indicating that glucuronide conjugates may have partially contributed to direct mutagenicity. Experiments using scavengers of reactive oxygen species revealed mainly via hydroxyl radicals. The results clearly demonstrate that tobacco processors are exposed to a wide spectrum of mutagens that cause frame-shift, base pair substitution and oxidative damage

    THE EFFECT OF CHAVYADI CHURNAM AND MUSTAKARISHTA IN MANAGEMENT OF GRAHANI W.S.R. TO IRRITABLE BOWEL SYNDROME

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    Grahani roga described in classical text books of Ayurveda represents a group of disorders of digestive system caused by impairment of Agni. Imbalance of Agni and Samanavata are the most predominant factors involved in the pathogenesis of Grahani roga. The cardinal features of Grahani explained in the clinical text books of Ayurveda, have at most similarities with the clinical features of Irritable Bowel Syndrome (IBS) explained in western medicine.The study “A clinical study to evaluate the combined effect of Chavyadi Churnam Mustakarishta in Grahani w.s.r.to IBS” was undertaken to evaluate the combined effect of Mustakarishta and Chavyadichurnam in Grahani, with a stipulated time period of 40 days. One more observation after 3 months completion of treatment was made without any intervention to check the relapses if any.In this study 30 patients were incidentally selected and assigned under a single group by confirming the clinical features of Grahani along with Rome II criteria. In the intervention Chavyadi Churna was administered 3 gms twice in a day with Takra as Anupana and Mustakarishta, 15ml twice daily after food with equal water. Overall 26 patients (86.6%) got complete relief, 4 patients (13.3%) got moderate relief. The results obtained on the parameters of study were highly significant with p< 0.001. At the end with these obtained results it can be concluded that the combination of Chavyadi Churnam and Mustakarishta are very effective in the management of Vataja Grahani i.e. IBS

    Using Transcranial Magnetic Stimulation (TMS) to Compare Cortical Excitability Among Depressed Patients, Sleep-Deprived Controls, and Rested Controls

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    Objective: To compare cortical excitability among sleep-deprived and rested controls, and depressed subjects. Methods: 3 controls and 4 depressed patients (average HAM-D 19) wererecruited. Sleep-deprived controls were instructed to sleep \u3c=4 hours the previous night. TMS-produced motor evoked potentials (MEPs) were measured before and after subjects engaged in sets of non-fatiguing manual exercise. Results: Post-exercise MEP increased 71+1-19% for rested controls, 28+1-32% for sleep deprived controls, and 8+1-15% for depressed patients. This increase, facilitation, was significantly greater in rested controls than in depressed patients (p=0.011). No significant difference in facilitation was found between sleep-deprived controls and depressed patients. Conclusion: Sleep-deprivation may partially account for reduced cortical excitability in depressed patients

    FORMULATION AND IN VITRO EVALUATION OF DAPAGLIFLOZIN AND SAXAGLIPTIN BILAYERED TABLETS

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    Dapagliflozin (DG) is a sodium glucose cotransporter-2 (SGLT-2) inhibitor and Saxagliptin (SG) is a dipeptidyl peptidase-4 (DPP-4) inhibitor. The aim of the present work is to formulate a bilayered tablet (BT) of DG as immediate release (IR) layer and SG as sustained release (SR) layer by direct compression method for the effective treatment of type 2 diabetes mellitus. Type and concentration of superdisintegrant among [sodium starch glycolate (SSG)/Lycoat RS720/ Ludiflash] was optimized to enhance the dissolution rate (DR) of DG from the IR layer of BT. Type and concentration of SR polymer among (Carbapol 940/ Karaya gum/ HPMC K15M) was optimized to extend the release of SG up to 12 h with zero order release profile from the SR layer of BT. It was concluded that the optimization of the ratio of SG: SR polymer (HPMC K15M), had significant effect on extending the release profiles of SG. The ratio of SG: HPMC K15M at 1:18 respectively forms a better matrix for the extending the release of SG up to 12 h from the SR layer of BT. The optimized formulation; BT9 [IR9 (6% w/w Ludiflash as superdisintegrant and SR9 (with 60% HPMC K15M as SR polymer)] releases 100% of DG from the IR layer with in 45 min and extends the release of SG up to 12 h with a better zero order release profile (r2=0.994). It passes the accelerated stability studies as per ICH guidelines. A combination of these two classes [SGLT-2 inhibitors (DG) and DPP-4 inhibitors (SG)] of glucose-lowering agents and formulating them as a BT is more effective in the treatment and maintenance of type 2 diabetes mellitus

    Alternative management in a case of placenta accreta with previous caesarean

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    The rate of caesarean is increasing day by day, and with it the chance of repeat caesarean. This has led to a rise in the chance of occurrence of placenta accreta. Control of bleeding is the main goal in such cases, which usually necessitates hysterectomy. But alternative methods are useful when retaining fertility is important. We present this case of a 30 yr old female who was admitted as a case of central placenta previa with previous caesarean. Per operatively, placenta was attached along the incision and baby was delivered by separating the placenta attached above the upper margin of incision. On attempting to remove the placenta attached to lower part of incision, it was found to be adherent along the previous scar. So placenta was removed piece meal, some part was left behind. Box sutures were taken over that part and uterine packing was done to control the bleeding. Post operatively the patient was fine and given injection Methotrexate on 8th day following the regime of 1, 3, 5, 7 days. She failed to expulse the placenta by 6wks, so D&E was done and retained products were removed. Leaving the placenta in situ followed by Methotrexate and interval removal of placenta can thus be helpful in conserving the uterus and hence, the fertility

    Numerical Simulation of Flow Past a Prolate Spheroid

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    The prolate spheroid is geometrically very simple but the flow characteristics are complex which are dominated by transition and three-dimensional separation phenomenon having both primary and secondary vortex. The transition phenomenon in this flow is triggered due to the stream wise Tollmien-Schlichting (T-S) wake instability and cross flow instability, which makes the prediction more challenging due to lack of effective predictive tool to model transition. The present work aims at simulating numerically the three-dimensional turbulent flow past 6:1 prolate spheroid at Re=4.2 x 106 using RANS approach for which experimental data are available in literature. These simulations have been carried out using parallel version of the in-house multiblock structured incompressible flow solution code 3D-PURLES (3D Pressure based Unsteady Reynolds Average Navier Stokes and LES solver)

    PHYTOCHEMICAL STUDY OF GOKSHUR (TRIBULUS TERRESTRIS LINN.) AND EVALUATION OF ITS ANTIBACTERIAL ACTIVITY WITH SPECIAL REFERENCE TO MUTRAKRUCHCHA

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    Infection of the urinary tract is the second commonest site after respiratory tract infection. It is more frequent in women than men. Almost 50% women suffer UTI. In our classical texts, urinary tract infection is described as Mutrakruchcha. A great Acharya Charak has mentioned it in Chikitsa sthana, Trimarmiya adhyay, its 8 types and Basti as a Marma. For the treatment of all types of Mutrakruchcha, Gokshur is mentioned. Gokshur is diuretic, aphrodisiac, tonic and rejuvenating herb with the ability to build lean muscle and strength. Gokshur possess Madhur rasa, Madhur vipaka and sheet Virya which causes diuresis by increasing Kleda in the body. So in this study 30 patients complaining of urinary tract infection were taken. 50 ml of Gokshur decoction, twice a day was given orally for 30 days. Weekly assessment was done on the basis of sign and symptoms like Mutra daha (burning micturition), Sashula mutrapravruti (painful micturition), Bastishul (suprapubic pain), Mutrapravruti (frequency of micturition), Jwaraprachiti (fever with chills), Sarakta mutrapravruti (haematuria), Sapuya mutrapravruti (pyuria). Objective improvement was done on the basis of reduction in pus cells in urine and serum creatinine at initial and after 30 days. Subjective improvement was shown in percentage it was 67.71%. The observations were found to be significant. Paired t test was found to be highly significant at 1 % level of significance i. e. p < 0. 01

    Mutagenic potential of Indian tobacco products

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    The mutagenic potential of aqueous extracts of masheri (ME), chewing tobacco alone (CTE) and a mixture of chewing tobacco plus lime (CTLE) was tested using the Ames assay. ME exhibited mutagenicity in Salmonella typhimurium TA98 upon metabolic activation with aroclor-1254-induced rat liver S9, while nitrosation rendered it mutagenic in TA100 and TA102. CTE exhibited borderline mutagenicity in the absence or presence of S9 in TA98 and TA100 and after nitrosation in TA102, while nitrosation led to doubling of TA98 and TA100 revertants. In contrast, CTLE exhibited direct mutagenicity in TA98, TA100 and TA102, was mutagenic to TA98 upon S9 addition and induced mutagenic responses in all three tester strains after nitrosation. Experiments using scavengers of reactive oxygen species (ROS) suggested that CTLE-induced oxidat-ive damage in TA102 was mediated by a variety of ROS. The high mutagenic potency of CTLE vis a vis that of CTE may be attributed to changes in the pH leading to differences in the amount and nature of compounds extracted from tobacco. Thus, exposure to a wide spectrum of tobacco-derived mutagcns and promutagens may play a critical role in the development of oral cancer among users of tobacco plus lime
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