Magnetic Fields and Afterglows of BdHNe: Inferences from GRB 130427A, GRB 160509A, GRB 160625B, GRB 180728A and GRB 190114C

GRB 190114C is the first binary-driven hypernova (BdHN) fully observed from the initial supernova appearance to the final emergence of the optical SN signal. It offers an unprecedented testing ground for the BdHN theory and it is here determined and further extended to additional gamma-ray bursts (GRBs). BdHNe comprise two subclasses of long GRBs with progenitors a binary system composed of a carbon-oxygen star (CO$_\textrm{core}$) and a neutron star (NS) companion. The CO$_\textrm{core}$ explodes as a SN leaving at its center a newborn NS ($\nu$NS). The SN ejecta hypercritically accretes both on the $\nu$NS and the NS companion. BdHNe I are the tightest binaries where the accretion leads the companion NS to gravitational collapse into a black hole (BH). In BdHN II the accretion onto the NS is lower, so there is no BH formation. We observe the same structure of the afterglow for GRB 190114C and other selected examples of BdHNe I (GRB 130427A, GRB 160509A, GRB 160625B) and for BdHN II (GRB 180728A). In all the cases the explanation of the afterglow is reached via the synchrotron emission powered by the $\nu$NS: their magnetic fields structures and their spin are determined. For BdHNe I, we discuss the properties of the magnetic field embedding the newborn BH, inherited from the collapsed NS and amplified during the gravitational collapse process, and surrounded by the SN ejecta.Comment: 7 figures, 3 tables, submitted to Ap

Association of mutations in the basal core promoter and pre-core regions of the hepatitis B viral genome and longitudinal changes in HBV level in HBEAG negative individuals: Results from a cohort study in northern Iran

Background: Although certain HBV mutations are known to affect the expression of Hepatitis e antigen, their association with HBV viral level or clinical outcomes is less clear. Objectives: We evaluated associations between different mutations in the Basal Core promoter (BCP) and Pre-core (PC) regions of HBV genome and subsequent changes in HBV viral DNA level over seven years in a population of untreated HBeAg negative chronic hepatitis B (CHB) participants in Northeast of Iran. Materials and Methods: Participants in the current study were drawn from the Golestan Hepatitis B Cohort Study (GHBCS), a cohort of approximately 2590 HBsAg positive subjects (living in Gonbad city) embedded in the Golestan Cohort Study (GCS). At baseline, HBsAg was measured in all participants and revealed 2590 HBsAg positive cases. We randomly selected 304 participants who their blood sample were taken at both baseline and seven years later in follow-up and had not been treated for HBV during this time. HBV viral load were assessed at baseline and at year 7. The BCP and PC regions of the HBV DNA, at baseline, were amplified via hemi-nested PCR and sequenced by cycle sequencing. At year 7, liver stiffness was assessed by fibroscan; also, other parameters of liver disease were assessed following standard clinical protocols. Associations were assessed via tabulation, chi-square, t-tests and logistic regression. P values < 0.05 were considered statistically significant and all tests were two-sided. Results: Among 304 HBsAg positive participants, 99 had detectable HBV DNA at study baseline. Of these, 61.6% had PC mutations (48.5% A1896 and 25.2% G1899). In contrast to other mutations, A1896 was associated with a higher proportion of detectable HBV DNA at year 7 (39.6%) compared to patients with the wild type (13.7%) (OR: 4.36, CI95% = 1.63-11.70; P Value = 0.002). Although participants with the A1896 mutation had higher year-7 HBV viral load than participants with G1896 (2.30 ± 1.66 IU/mL vs. 1.76 ± 1 IU/mL among patients with detectable HBV; P value = 0.052), no association was observed with either serum level ALT or liver stiffness. Interestingly, mutations in the basal core promoter (BCP) region had no significant effect on virus DNA detection. Conclusions: In this population with chronic HBeAg negative hepatitis B, an association was observed between the G1896A mutation in the Pre-core region of HBV and subsequent level of HBV DNA seven years later, which indicated that mutations in this region of HBV genome may contribute to disease progression in these patients and play an important role in HBV natural course of disease. © 2015, Kowsar Corp

The newborn black hole in GRB 191014C proves that it is alive

A multi-decade theoretical effort has been devoted to finding an efficient mechanism to use the rotational and electrodynamical extractable energy of a Kerr-Newman black hole (BH), to power the most energetic astrophysical sources such as gamma-ray bursts (GRBs) and active galactic nuclei (AGN). We show an efficient general relativistic electrodynamical process which occurs in the "inner engine" of a binary driven hypernova (BdHN). The {inner engine} is composed of a rotating Kerr BH of mass $M$ and dimensionless spin parameter $\alpha$, a magnetic field of strength $B_0$ aligned and parallel to the rotation axis, and a very low-density ionized plasma. Here, we show that the gravitomagnetic interaction between the BH and the magnetic field induces an electric field that accelerates electrons and protons from the environment to ultrarelativistic energies emitting synchrotron radiation. We show that in GRB 190114C the BH of mass $M = 4.4~M_\odot$, $\alpha= 0.4$, and $B_0 \approx 4\times 10^{10}$ G can lead to a high-energy ($\gtrsim$GeV) luminosity of $10^{51}$ erg s$^{-1}$. The inner engine parameters are determined by requiring 1) that the BH extractable energy explains the GeV and ultrahigh-energy emission energetics, 2) that the emitted photons are not subjected to magnetic-pair production, and 3) that the synchrotron radiation timescale agrees with the observed high-energy timescale. We find for GRB 190114C a clear jetted emission of GeV energies with a semi-aperture angle of approximately $60^\circ$ with respect to the BH rotation axis.Comment: Matches version to appear in A&

Distance-generalized Core Decomposition

The $k$-core of a graph is defined as the maximal subgraph in which every vertex is connected to at least $k$ other vertices within that subgraph. In this work we introduce a distance-based generalization of the notion of $k$-core, which we refer to as the $(k,h)$-core, i.e., the maximal subgraph in which every vertex has at least $k$ other vertices at distance $\leq h$ within that subgraph. We study the properties of the $(k,h)$-core showing that it preserves many of the nice features of the classic core decomposition (e.g., its connection with the notion of distance-generalized chromatic number) and it preserves its usefulness to speed-up or approximate distance-generalized notions of dense structures, such as $h$-club. Computing the distance-generalized core decomposition over large networks is intrinsically complex. However, by exploiting clever upper and lower bounds we can partition the computation in a set of totally independent subcomputations, opening the door to top-down exploration and to multithreading, and thus achieving an efficient algorithm

Electromagnetic emission of white dwarf binary mergers

It has been recently proposed that the ejected matter from white dwarf (WD) binary mergers can produce transient, optical and infrared emission similar to the "kilonovae" of neutron star (NS) binary mergers. To confirm this we calculate the electromagnetic emission from WD-WD mergers and compare with kilonova observations. We simulate WD-WD mergers leading to a massive, fast rotating, highly magnetized WD with an adapted version of the smoothed-particle-hydrodynamics (SPH) code Phantom. We thus obtain initial conditions for the ejecta such as escape velocity, mass and initial position and distribution. The subsequent thermal and dynamical evolution of the ejecta is obtained by integrating the energy-conservation equation accounting for expansion cooling and a heating source given by the fallback accretion onto the newly-formed WD and its magneto-dipole radiation. We show that magnetospheric processes in the merger can lead to a prompt, short gamma-ray emission of up to $\approx 10^{46}$ erg in a timescale of $0.1$-$1$ s. The bulk of the ejecta initially expands non-relativistically with velocity $0.01 c$ and then it accelerates to $0.1 c$ due to the injection of fallback accretion energy. The ejecta become transparent at optical wavelengths around $\sim 7$ days post-merger with a luminosity $10^{41}$-$10^{42}$ erg s$^{-1}$. The X-ray emission from the fallback accretion becomes visible around $\sim 150$-$200$ day post-merger with a luminosity of $10^{39}$ erg s$^{-1}$. We also predict the post-merger time at which the central WD should appear as a pulsar depending on the value of the magnetic field and rotation period.Comment: 12 pages, Accepted for publication in JCA

GRB 170817A-GW170817-AT 2017gfo and the observations of NS-NS, NS-WD and WD-WD mergers

The LIGO-Virgo Collaboration has announced the detection of GW170817 and has associated it with GRB 170817A. These signals have been followed after 11 hours by the optical and infrared emission of AT 2017gfo. The origin of this complex phenomenon has been attributed to a neutron star-neutron star (NS-NS) merger. In order to probe this association we confront our current understanding of the gravitational waves and associated electromagnetic radiation with four observed GRBs originating in binaries composed of different combinations NSs and white dwarfs (WDs). We consider 1) GRB 090510 the prototype of NS-NS merger leading to a black hole (BH); 2) GRB 130603B the prototype of a NS-NS merger leading to massive NS (MNS) with an associated kilonova; 3) GRB 060614 the prototype of a NS-WD merger leading to a MNS with an associated kilonova candidate; 4) GRB 170817A the prototype of a WD-WD merger leading to massive WD with an associated AT 2017gfo-like emission. None of these systems support the above mentioned association. The clear association between GRB 170817A and AT 2017gfo has led to introduce a new model based on on a new subfamily of GRBs originating from WD-WD mergers. We show how this novel model is in agreement with the exceptional observations in the optical, infrared, X- and gamma-rays of GRB 170817A-AT 2017gfo.Comment: version accepted for publication in JCAP. Missing references adde

Combined efficacy of silver nanoparticles and commercial antibiotics on different phylogenetic groups of Escherichia coli

NO ABSTRACT AVAILABLESilver nanoparticles (Ag-NPs) can attach to flexible polymeric chains of antibiotics, hence it can be used in combination with antibiotics against resistant bacteria. In this study, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and MBC/MIC ratio of Ag-NPs and antibiotics (gentamicin, tetracycline, erythromycin, ciprofloxacin, nalidixic acid, cefixime, cephalexin, amoxicillin, ampicillin, and penicillin) were quantified against 50 Escherichia coli isolates (25 human urinary tract infection and 25 avian colibacillosis). All isolates had been assigned as four phylogenetic groups A, B1, B2, and D. The results showed that the majority of the human and broiler isolates belonged to phylogenetic groups A and B2. MBC/MIC ratio of Ag-NPs in combination with antibiotics was assessed. It was found that the MIC of the majority of broiler isolates to Ag-NPs was equal to or greater than 50 μg/ml. To conclude, a combination of penicillin and ciprofloxacin with Ag-NPs exhibited profound impact against isolates, the combinations might be applicable for treating multidrug-resistant bacteria

Pattern of mandibular third molar impaction: A cross‑sectional study in northeast of Iran

Objectives: Impacted teeth, if left untreated, have a potential to induce various complications. The aim of the current study was to determine the prevalence and pattern of impacted mandibular third molar in the Iranian population.Study Design: This cross‑sectional study was performed in patients who were referred to the Department of Oral Radiology between July 2009 and October 2010 to obtain an orthopantomogram (OPG). Data were collected regarding age and gender, prevalence of impacted mandibular third molars, angulation of impacted teeth (Winter’s classification), level of impaction (Pell and Gregory classification), and relationship of the mandibular third molar with the ramus (Pell and Gregory classification). The collected data were analyzed using SPSS software version 11.0 with a confidence interval of 95%.Results: Among the 1433 patients included in the study, 489 (34.12%) patients were male and 944 (65.88%) were female. Of the total OPGs performed, 871 (60.78%) OPGs demonstrated at least one impacted mandibular third molar. In addition, of the 2866 mandibular third molars investigated, 1397 (48.74%) were found to be impacted. A significant association was observed between gender and the number of impacted teeth or the presence of impaction of any mandibular tooth (or teeth) (P &lt; 0.05). The most common type of tooth angulation was mesioangular (48.67%). In addition, the most prevalent type of impaction level and ramus relationship was level B (63.85%) and Class II (48.46%), respectively. There were no significant differences between the two sides of the mandible for the prevalence of impacted third molar (P &gt; 0.05).Conclusion: The pattern of mandibular third molars in the Northeast region of Iran revealed a high prevalence of impaction, which was mostly mesioangular, level B, and Class II with a gender predilection for females.Keywords: Impaction, Iran, mandibular third molar, orthopantomogram, patter