Representations and Positive Definite Functions on Hypergroups

Some relationships between representations of a hypergroup X, its algebras, and positive definite functions on X are studied. Also, various types of convergence of positive definite functions on X are discussed

Degradation of human kininogens with the release of kinin peptides by extracellular proteinases of Candida spp.

The secretion of proteolytic enzymes by pathogenic microorganisms is one of the most successful strategies used by pathogens to colonize and infect the host organism. The extracellular microbial proteinases can seriously deregulate the homeostatic proteolytic cascades of the host, including the kinin-forming system, repeatedly reported to he activated during bacterial infection. The current study assigns a kinin-releasing activity to secreted proteinases of Candida spp. yeasts, the major fungal pathogens of humans. Of several Candida species studied, C. parapsilosis and C. albicans in their invasive filamentous forms are shown to produce proteinases which most effectively degrade proteinaceous kinin precursors, the kininogens. These enzymes, classified as aspartyl proteinases, have the highest kininogen-degrading activity at low pH (approx. 3.5), but the associated production of bradykinin-related peptides from a small fraction of kininogen molecules is optimal at neutral pH (6.5). The peptides effectively interact with cellular B2-type kinin receptors. Moreover, kinin-related peptides capable of interacting with inflammation-induced B1-type receptors are also formed, but with a reversed pH dependence. The presented variability of the potential extracellular kinin production by secreted aspartyl proteinases of Candida spp. is consistent with the known adaptability of these opportunistic pathogens to different niches in the host organism

Wind reduction patterns around isolated biomass for wind erosion control in a desertified area of Central Sudan

The aim of this study was to assess the effectiveness of sparse vegetation, feature common in arid zone, to reduce wind force (velocity) and hence protect the surface and regions downwind from drifting sand and their consequences. Respectively 4 (with heights h of 4, 3.2, 2 and 1.66 m), 2 (with h of 3 and 2.5 m) and 3 (with h of 1.04, 0.9 and 0.8 m ) well established single biomass configurations of Leptadenia pyrotechnica trees, Prosopis juliflora trees and Panicum turgidum grass, were selected in the field. Solar powered cup anemometer wind measurements with a data logger system were taken at heights of 0.25 and 0.5 h, at distances 0.5 and 1 h, at four sides of the tree in the prevailing wind direction and perpendicular to it, and additionally at 2, 4 and 6 h windward and leeward. The protection effectiveness of the biomass was calculated as a wind reduction ratio and in terms of objects protection, which was evaluated using the dimensionless protection index (É). The study showed that windward protection provided by Leptadenia and Prosopis at level 0.25h and distance 0.5 h was similar, w ith a wind reduction ratio R0.8, while Panicum showed comparably higher R-values. Even at the 0.5 h level, Panicum showed an R of 0.65 at 0.5 h distance. Leew ard, at 0.25 h level differences were small, R increasing from 0.6/0.7 to 0.8/1 with distance, Leptadenia protecting best. At higher level (0.5 h) at distances 0.5 and 1 h Prosopis gave better protection than the other two at distances 0.5, 1 and 2 h. The research is an exam ple of simple experimental work under difficult environmental conditions in Africa. It was part of studies in which additional attention was paid to quantification aspects under such conditions as well as to the problems it helped solve in the African societies concerned as agrometeorological service

Correlation between broiler lameness and anatomical measurements of bone using radiographical projections with assessments of consistency across and within radiographs

Lameness represents a major welfare and production issue in the poultry industry with a recent survey estimating 27% of birds lame and 3% unable to walk by 40 d of age. A variety of factors may induce lameness and are typically grouped into 2 broad classes on the basis of being infectious or skeletal in nature with the latter accounting for the majority of cases. The current work sought to build upon a large body of literature assessing the anatomical properties of bone in lame birds. Our specific objectives sought to identify relationships between relevant anatomical properties of the tibia and metatarsus using digital quantification from radiographs of legs and a measure of walking difficulty. Resulting output was statistically analyzed to assess 1) observer reliability for consistency in placing the leg during the radiograph procedure and quantification of the various measures within a radiograph, 2) the relationship between the various measurements of anatomical bone properties and sex, bird mass, and gait score, and 3) the relationship between each measurement and leg symmetry. Our anatomical bone measures were found to be reliable (intra-rater and test-retest reliabilities < 0.75) within radiograph for all measures and 8 of the 10 measures across radiographs. Several measures of bone properties in the tibia correlated to difficulty walking as measured by gait score (P < 0.05), indicating greater angulations with increasing lameness. Of the measures that manifested a gait score × bird mass interaction, heavier birds appeared to exhibit less angulation with increasing difficulty walking with lighter birds the opposite. These interactions suggest possibilities for influencing effects of activity or feed intake on bone mineralization with the bone angulation observed. Our efforts agree with that of others and indicate that angulation of the tibia may be related to lameness, though subsequent efforts involving comprehensive measures of bird activity, growth rates, and internal bone structure will be needed if the validity of the measures are to be accepte