Application of Kozeny-Carman Equation to Estimate Saturated Hydraulic Conductivity of an Alfisol at Samaru and a Cambisol at Kadawa, Nigeria

Kozeny-Carman equation was used to estimate field and laboratory determined saturated hydraulic conductivity (Ks) based on Pe values obtained from soils of two Northern Savanna ecological zones of Nigeria (Samaru and Kadawa). Total porosity was determined from measured dry bulk density (Db), particle density (Dp) and moisture content at –33kPa pressure potential. Effective porosity was calculated as the difference between total porosity and volumetric moisture at -33kpa. The Ks and Pe values were fitted into the Kozeny-Carman equation using the linear least square fitting. In Samaru, 91.7 and 61% variation of Ks were explained respectively from field (Kfs) and laboratory measurements (Kls) while 61% variation of Ks was explained from the average values of laboratory measurement for Kadawa. The proportionality constant (β) varied widely between 7.1 × 10-3 to 6918.30 while the fitting parameters (n) varied from values < 1 to 2.37. The Relative Effective Porosity (REP) was adapted to substitute Pe in the Kozeny-Carman equation. Only field measured data (r2 = 0.881) and laboratory measured data (r2 = 0.573) from Samaru fit into the model and the regression coefficients were not improved. The REP- Model did not perform well with the data presented in this study

Implementation of Patient Safety Culture Survey in Jombang Islamic Hospital

Patient safety is the indicator of healthcare service quality. To improve patient-safety culture in hospital, conducting a survey is important to determine which dimension should be managed. Jombang Islamic Hospital (Rumah Sakit Islam Jombang) has an established Patient Safety Team since 2011, but the patient-safety culture is still low because only three incidents were reported in 2015. This study aims to measure patient-safety culture in hospital to identify the factors that need to be improved in hospital unit. This was a descriptive analytic study. Primary data were collected in 2016 using an Indonesian-translated version of Hospital Survey on Patient SafetyCulture (HSOPSC) questionnaire. The HSOPSC measures 12 patient safety dimensions. The respondents were 117 Jombang Islamic Hospital staff members who work in hospital unit that gives a direct medical service. Questionnaire's final response rate was 91%. The overall average positive response in Jombang Islamic Hospital was 68%, slightly higher than the average positive response for the AHRQ database report in 2016 (65%). Pharmacy had the lowest positive response (54%), while Obstetric and Operation Room had the highest positive response (83%). The dimension that received the highest percentage of positive response was ‘Teamwork within units’ that reached 94% and the lowest was ‘Staffing’ with only 34%. This study concludes that the staff members feel positive toward patient-safety culture. It is important to give an intervention to hospital unit and dimensions that received low percentage of positive response in order to achieve better healthcare service quality. Keywords: HSOPSC, hospital dimension, patient safety culture, surve

Introducing a Manipulated System of Drainage Basins of a Developing Countries

As a natural open system, in a drainage basin, there is water flow and balanced channel characteristics. In a manipulated channel system, however, according to Mrowka (1974) and Schumm (1977), the water flow is made under control that induces dynamics in channel characteristics. In this paper, attempt is made to uncover how channel project is caused, nature of the new forms of channel cross-sectional area, shape, sinuosity, and gradient, as well as flood-plain characteristics. It also covers the peculiar transformation evolved as drainage basin system is changed to channel project. Consequently in the paper, two tasks involved were explained. These are significant channel re-construction, and redirection of stream flow as relates to developing water terrace in the savanna zone of Nigeria with the increased channel project dated back 1970s (Olofin, 1980). Specifically, the paper drew considered the physical characteristics of the natural channel of River Suka in North Central Nigeria and the manipulated system or the new face of the drainage basin project of the Kano River, Nigeria used to structure the Tiga dam that involved downstream channel adjustments Keywords: drainage basin, channel, river, dam, downstrea

Evaluation of neutrophil gelatinase associated lipocalin (NGAL) in type 2 diabetic patients with diabetic nephropathy

Diabetic nephropathy (DN) is a devastating chronic microvascular complication that represents the major cause of end-stage renal failure leading to the development and progression of diabetic syndrome. Aim: The aim of this study was to evaluate serum neutrophil gelatinase associated lipocalin (NGAL) in type 2 DM with diabetic nephropathy. Methods: Eighty (80) type 2 diabetic patients with DN and apparently healthy controls were respectively recruited. Blood samples were collected and tested for serum NGAL, creatinine, albumin, fasting plasma glucose and HbA1c. Creatinine and albumin were analyzed using Abbot autoanalyser, HbA1c was analyzed using fine care system and serum NGAL using the ELISA method. Estimated GFR (eGFR) was calculated using the modification of diet in renal disease (MDRD) formula. Statistical analysis was performed using statistical package for social science (SPSS) software version 20.0. Student t-test, one way analysis of variance (ANOVA) and Pearson’s correlation were used for comparisons and correlation of data respectively with level of significance set <0.05. Result: The mean values of the serum NGAL, FPG, HbA1c, BMI and eGFR in both DN group and control group were found to be 3.72±2.62 vs 1.08±0.78μg/ml, 7.06 ±3.46 vs 4.08± 0.39mmo/l, 6.73±1.08 vs 4.71 ±0.39%, 27.33±5.29 vs 25.08±3.65ml/min/1.73m2 and 76.57 ±11.20 vs 118.23 ±12.11ml/min/1.73m2 respectively. The study found a high and significant difference in the mean values of the DN group compared to the control group. A positive and significant relationship was observed between serum NGAL and eGFR and duration of diagnosis of diabetes mellitus. Conclusion: Serum NGAL could therefore be used as a biomarker to diagnose DN even earlier to incipient nephropathy, NGAL, Diabetes nephropathy, eGFR, Microalbuminuria, Glycated haemoglobin

Determination of Some Selected Physical Properties of Different Maize Varieties (Zea Mays) Related to Design of Processing Machines of Nigeria

Abstract: The design related physical properties of six-selected Improved Institute for Agricultural Research Maize varieties were investigated. The properties will enhance design and development of production, processing and storage equipment for the crop. The mean results obtained for the different collections ranged from 7.42 to 15.63%, 8.2mm to 10.4mm, 7.1 to 9.1mm, 4.0mm to 5.0mm, 6.6mm to 7.2mm, 133mm2to 161mm2, 0.62% to 0.81%, 0.46% to0.82%, 692.42kg/m3to 747.86kg/m3, 1162.54kg/m3 to1447.7kg/m3,37.79%to 46.69%, 203.62g to 306.86g, 170.09mm3to 234.59mm3, 35.8

Diffusion of e-health innovations in 'post-conflict' settings: a qualitative study on the personal experiences of health workers.

BACKGROUND: Technological innovations have the potential to strengthen human resources for health and improve access and quality of care in challenging 'post-conflict' contexts. However, analyses on the adoption of technology for health (that is, 'e-health') and whether and how e-health can strengthen a health workforce in these settings have been limited so far. This study explores the personal experiences of health workers using e-health innovations in selected post-conflict situations. METHODS: This study had a cross-sectional qualitative design. Telephone interviews were conducted with 12 health workers, from a variety of cadres and stages in their careers, from four post-conflict settings (Liberia, West Bank and Gaza, Sierra Leone and Somaliland) in 2012. Everett Roger's diffusion of innovation-decision model (that is, knowledge, persuasion, decision, implementation, contemplation) guided the thematic analysis. RESULTS: All health workers interviewed held positive perceptions of e-health, related to their beliefs that e-health can help them to access information and communicate with other health workers. However, understanding of the scope of e-health was generally limited, and often based on innovations that health workers have been introduced through by their international partners. Health workers reported a range of engagement with e-health innovations, mostly for communication (for example, email) and educational purposes (for example, online learning platforms). Poor, unreliable and unaffordable Internet was a commonly mentioned barrier to e-health use. Scaling-up existing e-health partnerships and innovations were suggested starting points to increase e-health innovation dissemination. CONCLUSIONS: Results from this study showed ICT based e-health innovations can relieve information and communication needs of health workers in post-conflict settings. However, more efforts and investments, preferably driven by healthcare workers within the post-conflict context, are needed to make e-health more widespread and sustainable. Increased awareness is necessary among health professionals, even among current e-health users, and physical and financial access barriers need to be addressed. Future e-health initiatives are likely to increase their impact if based on perceived health information needs of intended users

Composition and Distribution of Mosquito Vectors in a Peri-Urban Community Surrounding an Institution of Learning in Lafia Metropolis, Nasarawa State, Central Nigeria

Vector surveillance is very key in solving mosquito-borne health problems in Nigeria. To this end, the composition and distribution of mosquito vectors in a peri-urban community surrounding an institution of learning in Lafia metropolis, Nasarawa State, Central Nigeria was carried out between December 2016 and June 2017. The Prokopack Aspirator was used to collect indoor resting mosquitoes between 6:00 a.m. and 9:00 a.m. from 30 randomly selected houses. Mosquitoes collected were knocked down and transferred into a well labelled petri-dish and taken to the laboratory for processing. A total of 664 mosquitoes were collected which spread across Culex quinquefasciatus 572 (86.14%), Anopheles gambiae 88 (13.25%) and Aedes aegypti 4 (0.60%). The abundance of mosquitoes in relation to seasons, species, sex, abdominal conditions as well as transmission indices across seasons significantly varied (P 0.05). The inhabitants of the area should ensure that all drainages flow through so as to reduce mosquito breeding grounds. Also, members of the community should always protect themselves by sleeping under insecticide treated bed nets

The Critical Need for Pooled Data on Coronavirus Disease 2019 in African Children: An AFREhealth Call for Action Through Multicountry Research Collaboration

Globally, there are prevailing knowledge gaps in the epidemiology, clinical manifestations, and outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among children and adolescents; and these gaps are especially wide in African countries. The availability of robust age-disaggregated data is a critical first step in improving knowledge on disease burden and manifestations of coronavirus disease 2019 (COVID-19) among children. Furthermore, it is essential to improve understanding of SARS-CoV-2 interactions with comorbidities and coinfections such as human immunodeficiency virus (HIV), tuberculosis, malaria, sickle cell disease, and malnutrition, which are highly prevalent among children in sub-Saharan Africa. The African Forum for Research and Education in Health (AFREhealth) COVID-19 Research Collaboration on Children and Adolescents is conducting studies across Western, Central, Eastern, and Southern Africa to address existing knowledge gaps. This consortium is expected to generate key evidence to inform clinical practice and public health policy-making for COVID-19 while concurrently addressing other major diseases affecting children in African countries

Assessment of Clinical Outcomes Among Children and Adolescents Hospitalized With COVID-19 in 6 Sub-Saharan African Countries

Importance: Little is known about COVID-19 outcomes among children and adolescents in sub-Saharan Africa, where preexisting comorbidities are prevalent. / Objective: To assess the clinical outcomes and factors associated with outcomes among children and adolescents hospitalized with COVID-19 in 6 countries in sub-Saharan Africa. / Design, Setting, and Participants: This cohort study was a retrospective record review of data from 25 hospitals in the Democratic Republic of the Congo, Ghana, Kenya, Nigeria, South Africa, and Uganda from March 1 to December 31, 2020, and included 469 hospitalized patients aged 0 to 19 years with SARS-CoV-2 infection. / Exposures: Age, sex, preexisting comorbidities, and region of residence. / Main Outcomes and Measures: An ordinal primary outcome scale was used comprising 5 categories: (1) hospitalization without oxygen supplementation, (2) hospitalization with oxygen supplementation, (3) ICU admission, (4) invasive mechanical ventilation, and (5) death. The secondary outcome was length of hospital stay. / Results: Among 469 hospitalized children and adolescents, the median age was 5.9 years (IQR, 1.6-11.1 years); 245 patients (52.4%) were male, and 115 (24.5%) had comorbidities. A total of 39 patients (8.3%) were from central Africa, 172 (36.7%) from eastern Africa, 208 (44.3%) from southern Africa, and 50 (10.7%) from western Africa. Eighteen patients had suspected (n = 6) or confirmed (n = 12) multisystem inflammatory syndrome in children. Thirty-nine patients (8.3%) died, including 22 of 69 patients (31.9%) who required intensive care unit admission and 4 of 18 patients (22.2%) with suspected or confirmed multisystem inflammatory syndrome in children. Among 468 patients, 418 (89.3%) were discharged, and 16 (3.4%) remained hospitalized. The likelihood of outcomes with higher vs lower severity among children younger than 1 year expressed as adjusted odds ratio (aOR) was 4.89 (95% CI, 1.44-16.61) times higher than that of adolescents aged 15 to 19 years. The presence of hypertension (aOR, 5.91; 95% CI, 1.89-18.50), chronic lung disease (aOR, 2.97; 95% CI, 1.65-5.37), or a hematological disorder (aOR, 3.10; 95% CI, 1.04-9.24) was associated with severe outcomes. Age younger than 1 year (adjusted subdistribution hazard ratio [asHR], 0.48; 95% CI, 0.27-0.87), the presence of 1 comorbidity (asHR, 0.54; 95% CI, 0.40-0.72), and the presence of 2 or more comorbidities (asHR, 0.26; 95% CI, 0.18-0.38) were associated with reduced rates of hospital discharge. / Conclusions and Relevance: In this cohort study of children and adolescents hospitalized with COVID-19 in sub-Saharan Africa, high rates of morbidity and mortality were observed among infants and patients with noncommunicable disease comorbidities, suggesting that COVID-19 vaccination and therapeutic interventions are needed for young populations in this region

Global Biobank Meta-analysis Initiative:Powering genetic discovery across human disease

Biobanks facilitate genome-wide association studies (GWASs), which have mapped genomic loci across a range of human diseases and traits. However, most biobanks are primarily composed of individuals of European ancestry. We introduce the Global Biobank Meta-analysis Initiative (GBMI)—a collaborative network of 23 biobanks from 4 continents representing more than 2.2 million consented individuals with genetic data linked to electronic health records. GBMI meta-analyzes summary statistics from GWASs generated using harmonized genotypes and phenotypes from member biobanks for 14 exemplar diseases and endpoints. This strategy validates that GWASs conducted in diverse biobanks can be integrated despite heterogeneity in case definitions, recruitment strategies, and baseline characteristics. This collaborative effort improves GWAS power for diseases, benefits understudied diseases, and improves risk prediction while also enabling the nomination of disease genes and drug candidates by incorporating gene and protein expression data and providing insight into the underlying biology of human diseases and traits.</p