Local and Global Superconductivity in Bismuth

We performed magnetization M(H,T) and magnetoresistance R(T,H) measurements on powdered (grain size ~ 149 micrometers) as well as highly oriented rhombohedral (A7) bismuth (Bi) samples consisting of single crystalline blocks of size ~ 1x1 mm2 in the plane perpendicular to the trigonal c-axis. The obtained results revealed the occurrence of (1) local superconductivity in powdered samples with Tc(0) = 8.75 \pm 0.05 K, and (2) global superconductivity at Tc(0) = 7.3 \pm 0.1 K in polycrystalline Bi triggered by low-resistance Ohmic contacts with silver (Ag) normal metal. The results provide evidence that the superconductivity in Bi is localized in a tiny volume fraction, probably at intergrain or Ag/Bi interfaces. On the other hand, the occurrence of global superconductivity observed for polycrystalline Bi can be accounted for by enhancement of the superconducting order parameter phase stiffness induced by the normal metal contacts, the scenario proposed in the context of "pseudogap regime" in cuprates [E. Berg et al., PRB 78, 094509 (2008)].Comment: 12 pages including 9 figures and 1 table, Special Issue to the 80th birthday anniversary of V. G. Peschansky, Electronic Properties of Conducting System

Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis.

Psoriatic arthritis (PsA) is a debilitating immune-mediated inflammatory arthritis of unknown pathogenesis commonly affecting patients with skin psoriasis. Here we use complementary single-cell approaches to study leukocytes from PsA joints. Mass cytometry demonstrates a 3-fold expansion of memory CD8 T cells in the joints of PsA patients compared to peripheral blood. Meanwhile, droplet-based and plate-based single-cell RNA sequencing of paired T cell receptor alpha and beta chain sequences show pronounced CD8 T cell clonal expansions within the joints. Transcriptome analyses find these expanded synovial CD8 T cells to express cycling, activation, tissue-homing and tissue residency markers. T cell receptor sequence comparison between patients identifies clonal convergence. Finally, chemokine receptor CXCR3 is upregulated in the expanded synovial CD8 T cells, while two CXCR3 ligands, CXCL9 and CXCL10, are elevated in PsA synovial fluid. Our data thus provide a quantitative molecular insight into the cellular immune landscape of psoriatic arthritis

­­­­­Geographical Distribution of Systemic Sclerosis in Canada: An Ecological Study based on the Canadian Scleroderma Research Group

Supplementary material for paper: Geographical Distribution of Systemic Sclerosis in Canada: An Ecological Study based on the Canadian Scleroderma Research GroupTHIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS DATASET CLICK ON THE DOI-LINK ABOV

Organic Solvent Exposure and Systemic Sclerosis: A Retrospective Cohort Study Based on the Canadian Scleroderma Research Group Registry

Supplementary material for paper "Organic Solvent Exposure and Systemic Sclerosis: A Retrospective Cohort Study Based on the Canadian Scleroderma Research Group Registry"THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS DATASET CLICK ON THE DOI-LINK ABOV