77 research outputs found

    Penilaian Sistem Informasi Akademik Menggunakan Model Cobit 4.1

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    Lembaga XYZ telah membuat sistem informasi akademik agar proses akademik berjalan lancar, namun selama ini belum ada penilaian pada sistem yang telah dibuat, apakah sistem itu sudah sesuai dengan standar pengelolaan IT atau belum. Karena itu penelitian ini menggunakan salah satu standar tata kelola TI yakni Cobit. Cobit Apabila tata kelola TI sesuai dengan standar yang diakui, maka pengelolaan dianggap layak dipercaya, Sehingga akan meningkatkan kepercayaan pengguna.. Adapun pendekatan yang digunakan adalah kualitatif dan kuantitatif. Pendekatan kualitatif dalam penelitian ini adalah data yang diperoleh melalui pengamatan (observasi) dan didasarkan pada penafsiran pemahaman peneliti secara subjektif. Hasil penilaian pada sistem yang diperoleh berada pada level 3 (defined). Artinya pemahaman pemakai (user) dalam menggunakan sistem belum merata dan terdapat masih ada kebijakan tata kelola IT yang belum lengkap

    Perbandingan Metode SAW dan TOPSIS pada Kasus UMKM

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    Dalam pengambilan keputusan terhadap masalah berdasarkan sebuah analisa pribadi yang subjektif tanpa menggunakan metode tertentu, biasanya memiliki tingkat kesalahan yang tinggi sehingga hal ini akan membahayakan pengambilan keputusan yang berujung pada penyesalan. Ada banyak metode Decision Support System (DSS) yang dapat digunakan untuk proses pengambilan keputusan, namun 2 metode yang sering digunakan untuk melakukan proses pengambilan keputusan yakni metode Simple Additive Weighting (SAW) dan Technique For Others Referencean by Similarity to Ideal Solution (TOPSIS). Karena itu untuk mengetahui yang terbaik dari 2 metode tersebut, maka dilakukan Perubahan pembobotan dan hasil pengujian diperoleh kesamaan dalam proses pengembilan keputusan (pemecahan masalah). Sehingga dalam pengambilan keputusan dapat menggunakan salah satu metode SAW atau TOPSIS. Perangkingan 2 metode tersebut akan menentukan lokasi yang strategis untuk meningkatkan omzet USAha percetakan (UMKM)

    Kenya adaptation to climate change in the arid lands: anticipating, adapting to and coping with climate risks in Kenya - operational recommendations for KACCAL

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    Years of concerted activism to bring awareness of climate change and its consequences to the fore of global concerns are finally yielding dividends. Until recently, most climate change activity focused on medium- to long-term projections regarding the nature and trajectory of change processes. With the uncertainties inherent in long-term climate projections and the difficulty of building political and economic momentum from hypothetical future scenarios, progress was slow. The recent past has, however, resulted in a drastic increase in extreme climate events across the globe that has wreaked untold humanitarian and economic havoc. The costly present day manifestations of climate change have catapulted climate concerns to the forefront of the global arena. The recent high-level event convened by the Secretary General of the United Nations to address the leadership challenge of climate change and build momentum for climate change talks (Bali, Indonesia, December 2007) is a clear indication that the urgency of climate change has fostered the degree of serious commitment it requires from the global agenda. Whatever its impacts, it is widely acknowledged that poor communities, already vulnerable to a suite of existing risks and endowed with meagre resources, will be the most adversely affected as climate change is superimposed on their already tenuous situation. In recognition of the need to help vulnerable populations in developing countries adapt to the adverse impacts of climate change, the Global Environment Facility (GEF), in conjunction with its partners, funds programmes aimed at reducing the vulnerability of countries to the impacts of climate change and helps them build adaptive capacity. The Kenya Adaptation to Climate Change in the Arid Lands (KACCAL) project is one such initiative supported in conjunction with the World Bank and the United Nations Development Programme (UNDP). About 80% of Kenya is arid or semi-arid and the main livelihood activities in these areas are pastoral, agropastoral and subsistence agriculture. Currently, these populations are among the poorest in Kenya, suffer from a weak natural resource base, are negatively affected by socio-economic and demographic trends that see a growing population depending on diminishing rangelands, and are relatively marginalized from the growing economy. Add to this the impacts of climate change, of which the recent severe and extended droughts of 2001, 2004–06 and the widespread flooding in 2007 are an early signal, and the livelihood threats to the communities of Kenya’s arid and semi-arid lands (ASAL) are clear and present

    The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation

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    Independent of its known role in NF-κB transcription, the HOIL-1L containing LUBAC is required for assembly and activation of the NLRP3 inflammasome via linear ubiquitination of ASC.Linear ubiquitination is a newly discovered posttranslational modification that is currently restricted to a small number of known protein substrates. The linear ubiquitination assembly complex (LUBAC), consisting of HOIL-1L, HOIP, and Sharpin, has been reported to activate NF-κB–mediated transcription in response to receptor signaling by ligating linear ubiquitin chains to Nemo and Rip1. Despite recent advances, the detailed roles of LUBAC in immune cells remain elusive. We demonstrate a novel HOIL-1L function as an essential regulator of the activation of the NLRP3/ASC inflammasome in primary bone marrow–derived macrophages (BMDMs) independently of NF-κB activation. Mechanistically, HOIL-1L is required for assembly of the NLRP3/ASC inflammasome and the linear ubiquitination of ASC, which we identify as a novel LUBAC substrate. Consequently, we find that HOIL-1L−/− mice have reduced IL-1β secretion in response to in vivo NLRP3 stimulation and survive lethal challenge with LPS. Together, these data demonstrate that linear ubiquitination is required for NLRP3 inflammasome activation, defining the molecular events of NLRP3 inflammasome activation and expanding the role of LUBAC as an innate immune regulator. Furthermore, our observation is clinically relevant because patients lacking HOIL-1L expression suffer from pyogenic bacterial immunodeficiency, providing a potential new therapeutic target for enhancing inflammation in immunodeficient patients

    A spatial econometric approach to designing and rating scalable index insurance in the presence of missing data

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    Index-Based Livestock Insurance has emerged as a promising market-based solution for insuring livestock against drought-related mortality. The objective of this work is to develop an explicit spatial econometric framework to estimate insurable indexes that can be integrated within a general insurance pricing framework. We explore the problem of estimating spatial panel models when there are missing dependent variable observations and cross-sectional dependence, and implement an estimable procedure which employs an iterative method. We also develop an out-of-sample efficient cross-validation mixing method to optimise the degree of index aggregation in the context of spatial index models

    Socio-Technical Innovation Bundles for Agri-Food Systems Transformation

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    Technological and institutional innovations in agri-food systems (AFSs) over the past century have brought dramatic advances in human well-being worldwide. Yet these gains increasingly appear unsustainable due to massive, adverse spillover effects on climate, natural environment, public health and nutrition, and social justice. How can humanity innovate further to bring about AFS transformations that can sustain and expand past progress, while making them healthier for all people and for the planet that must sustain current and future generations? This report was commissioned by the Cornell Atkinson Center for Sustainability in response to an invitation from the journal Nature Sustainability, which—in collaboration with its new sister journal, Nature Food—wanted to devote its 2020 expert panel to this topic. The panel brought together experts who come from many different continents and who span a wide range of disciplines and organizations—from industry and universities to social movements, governments, philanthropies, institutional and venture capital investors, and multilateral agencies. The panel synthesized the best current science to describe the present state of the world’s AFSs and key external drivers of AFS changes over the next 25–50 years, as well as tease out key lessons from the COVID-19 pandemic experience this year. As is increasingly widely recognized, the costs that farmers and downstream value chain actors incur and the prices consumers pay understate foods’ true costs to society once one accounts for adverse environmental, health, and social spillover effects. Inevitable demographic, economic, and climate change in the coming decades will catastrophically aggravate these problems under business-as-usual scenarios. Innovations will be needed to facilitate concerted, coordinated efforts to transition to more healthy, equitable, resilient, and sustainable AFSs
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