Effect of supervised exercise on physical function and balance in patients with intermittent claudication

Background The aim of the study was to identify whether a standard supervised exercise programme (SEP) for patients with intermittent claudication improved specific measures of functional performance including balance. Methods A prospective observational study was performed at a single tertiary vascular centre. Patients with symptomatic intermittent claudication (Rutherford grades 1–3) were recruited to the study. Participants were assessed at baseline (before SEP) and 3, 6 and 12 months afterwards for markers of lower-limb ischaemia (treadmill walking distance and ankle : brachial pressure index), physical function (6-min walk, Timed Up and Go test, and Short Physical Performance Battery (SPPB) score), balance impairment using computerized dynamic posturography with the Sensory Organization Test (SOT), and quality of life (VascuQoL and Short Form 36). Results Fifty-one participants underwent SEP, which significantly improved initial treadmill walking distance (P = 0·001). Enrolment in a SEP also resulted in improvements in physical function as determined by 6-min maximum walking distance (P = 0·006), SPPB score (P < 0·001), and some domains of both generic (bodily pain, P = 0·025) and disease-specific (social domain, P = 0·039) quality of life. Significant improvements were also noted in balance, as determined by the SOT (P < 0·001). Conclusion Supervised exercise improves both physical function and balance impairment

Long-term outcomes of a randomized clinical trial of supervised exercise, percutaneous transluminal angioplasty or combined treatment for patients with intermittent claudication due to femoropopliteal disease

Background: To compare the long-term outcomes of angioplasty (PTA), supervised exercise (SEP) and combined treatment (PTA+SEP) in patients with intermittent claudication (IC) due to femoropopliteal disease. Methods: Patients recruited to PTA, SEP and PTA+SEP arms of RCT were invited for long-term follow-up from 2010 to 2011.Indicators of limb ischaemia were recorded (ankle-brachial pressure indices, treadmill walking distances (ICD, MWD, PRWD). Duplex ultrasound was also performed. Patients completed SF36 and Vascuqol quality of life(QOL) questionnaires. Results: Of the 178 patients recruited in the trial, 139 were alive at the time of follow-up (PTA=46, SEP=47, PTA+SEP=46). Assessments were completed for 111 patients. Median time to follow-up was 5.2years (IQR 3.8-7.4years). Median age of patients at follow up was 75years. 62.2%(N=69) of patients were symptomatic.16.2%(N= 18) had experienced major cardiovascular event since their last follow-up visit. Intra-group analysis: Improvement was observed in ankle brachial pressure index (ABPI) in all groups. QOL outcomes were inconsistent across individual groups. Inter-group analysis: PTA and PTA+SEP groups demonstrated a significantly higher ABPI as compared to SEP group. No significant difference was observed in walking distances, QOL outcomes, restenosis rates, and new ipsilateral and contralateral lesions on duplex scan. Patients required re-interventions in all group (PTA=14, SEP=10, PTA+SEP=6). Number of re-interventions was higher in PTA group(N=29) as compared to SEP(N=17) and PTA+SEP(N=9) but failed to reach statistical significance. Conclusion: PTA, SEP and combined treatment are equally effective long-term treatment options for patients with femoropopliteal claudication. Addition of SEP to PTA can reduce the symptomatic restenosis and re-intervention rates

Removal of Solophenyl Red 3BL Dye from Textile Effluents by Adsorption Using a Natural Adsorbent Oxalis pes-caprae L.

The aim of the present study was to assess the adsorption potential of a natural adsorbent Oxalis pes-caprae L. for the removal of azo-dye solophenyl red 3BL (SR 3BL) from textile effluents. The adsorbent was characterized by Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). The effect of various parameters on the efficiency of the adsorption was studied. The optimum was found with the contact time of 35 minutes, pH of 6, and temperature of 25 °C. The equilibrium experimental data were fitted with the Langmuir, Freundlich, and Temkin models. Experimental data were well described with the Langmuir isotherm indicating monolayer adsorption. Pseudo-first-order, pseudo-second-order, and Elovich kinetic models were used to evaluate the adsorption kinetics. The adsorption kinetics was found to follow closely the pseudo-first-order kinetic model. Thermodynamics studies revealed that the adsorption process was spontaneous and exothermic. This work is licensed under a Creative Commons Attribution 4.0 International License

Percutaneous transluminal angioplasty results in improved physical function but not balance in patients with intermittent claudication

Objective The aim of this study was to identify whether revascularization by percutaneous transluminal angioplasty (PTA) for patients with intermittent claudication improved measures of functional performance including balance. Methods A prospective observational study was performed at a single tertiary vascular center. Patients with symptomatic intermittent claudication (Rutherford grades 1-3) were recruited to the study. Participants were assessed at baseline (pre-PTA) and then 3, 6, and 12 months post-PTA for markers of (1) lower limb ischemia (treadmill walking distances and ankle-brachial pressure index), (2) physical function (6-minute walk, Timed Up and Go, and chair stand time), (3) balance impairment using computerized dynamic posturography with the Sensory Organization Test, and (4) quality of life (VascuQoL and Short Form Health Survey [SF-36]). Results Forty-three participants underwent PTA. Over 12 months, a significant improvement was demonstrated in initial (P = .04) and maximum treadmill walking distance (P = .019). Physical functional ability improved across all outcome measures (P < .02), and some domains of both generic (P < .03) and disease-specific quality of life (P < .01). No significant improvement in balance was demonstrated by the Sensory Organization Test (P = .24). Conclusions Balance impairment is common in claudicants and does not improve with revascularization. Further research regarding effective treatment of balance impairment is required in this specific group of patients

Histopathological Study of Canine Mammary Tumours with Different Stain Tecniques

Mammary gland cancer is the most frequent Malignant tumor in human females and bitches and morbidity and mortality due to it continue to increase. Mammary gland carcinomas are quite heterogeneous in terms of morphology and biological behavior. Twenty-three female dogs were confirmed affected by mammary tumors during the period January 2014 - June 2015. In this study were used different stained technuques in mammary gland tumors of bitches to help us in diagnosing of them. The aim of this study was to compare H-E technique and Masson Trichrome staining technique in mammary gland tumors, in order to differentiate histological types of neoplastic lesions

Ruptures Du Tendon d’Achille Une étude rétrospective des ruptures de tendon d’Achille A propos de 137 cas

une étude rétrospective des ruptures de tendond’Achille à propos de 137 casintroduction :Le tendon d’Achille est le plus épais, le plusvolumineux et le plus résistant des tendons del’organisme. Il présente une zone étroite, Si lediagnostic clinique de la lésion est aisé, sontraitement reste sans consensusmateriel et methode :Il s’agit d’une étude rétrospective, concernant137 cas opérés au service de traumatologie orthopédiede centre hospitalo-universitaireFrance fanon entre 2001 et 2017résultats :Sur une période de 16 ans nous avons recensé137 cas de rupture du tendon d’Achille, ce quicorrespond à une fréquence de 8,6 cas par an.L’âge moyen dans notre série était de 38 ansavec sexe ratio H/F de 9 ; Activité sportive : 99cas soit 72.26 %.100patients ont bénéficié d’unsuture sous cutanée ; 33 patients ont bénéficiéd’un laçage, soit 89.1 %. La technique deBosworth a été réalisée dans 4 cas, soit 10.8 %.Elle a été nécessaire vue la faiblesse de la zonesuturée à cause d’un effilochement des deuxbouts.Discussion :La cause la plus fréquente des ruptures dutendon d’Achille est représentée par lesaccidents de sport ce qui a été rapporté danstoutes les séries de la littérature. Prédominancemasculine s’explique par une activité sportiveplus élevée chez les hommes.Dans notre série 37 patients ont bénéficié d’untraitement chirurgical à ciel ouvert utilisantdifférentes techniques : sutures simple avecsurjet de renforcement ou laçage pour lamajorité des cas .et 100 CAS réparationpercutanéeWeber et al et Farizon ont aussi privilégié lasuture et laçage avec un éventuel s’il existe unefragilité tendineuse.L’équipe du service de traumatologieorthopédie de l’hôpital  a utilisé,selon un article publié en 2003 la technique deBosworth .Lecestre, Rouvillain , Boukhrisetbeaucoup d’autres auteurs ont privilégié laténorraphie percutanée selon la technique deDelponte. Lansdaal et Assal , quant à eux ontutilisé la chirurgie mini invasive.Richard et al ont utilisé le traitementfonctionnel.Conclusion :Cretnik et al. , dans une étude comparantchirurgie à ciel ouvert versus ténorraphiepercutanée recommande cette dernière car elleapporte des résultats fonctionnels comparablesà la réparation ouverte, avec un tauxsensiblement inférieur de complications.Justin Lim a conclu que la réparationpercutanée est recommandée sur la base du bastaux de complications et l’aspect cosmétiqueamélioré

Fear of falling in claudicants and its relationship to physical ability, balance, and quality of Life

Objectives: Intermittent claudication is associated with poor physical function, quality of life (QoL), and balance impairment. Fear of falling (FoF) is a recognized contributing factor to poor physical ability. Any link between claudication and FoF is yet to be determined. This study aimed to explore the prevalence of FoF in claudicants and its relationship with physical function and QoL. Methods: A prospective observational study was performed. Fear of falling was determined using the Activities-specific Balance Confidence (ABC) questionnaire and the categorical question “Are you afraid of falling?” Physical ability and QoL (Short Form 36 and Vascular QoL) were determined. Results: A total of 161 claudicants (118 men, median age of 69 years) were assessed; 83 answered the categorical question “Are you afraid of falling?” By receiver–operating characteristic curve analysis, an ABC threshol

Towards supplier maturity evaluation in terms of PLM collaboration

The product lifecycle management (PLM) system has a significant role to support the collaboration and manage the partnership between OEM and Supplier to enable the success of supplier integration. Today great rates of co- operation as suppliers have been dedicated to SMEs. Since one of the PLM task is to control the collaboration between OEM and suppliers, this paper provide supplier (SMEs) a framework to find their place in this relationship in the concept of PLM. To respond to this trend, we defined a methodology based on collaborative matrix maturity levels and four PLM axes of strategic, organization, process and tools levels. Finally according to this ma- trix, we proposed a structure of a proper questionnaire and example that show suppliers how to evaluate their positions in terms of collaboration in PLM