431 research outputs found
Neural-net modeling for direct and inverse problems of shell theory
Effectiveness of the use of neural-net technology for the solving of shell theory problems is shown. Some results of neural-net interpolation and extrapolation for direct and inverse problems are discussed. Exact accuracy of neural-net solving opens wide latitude for shell constructions engineering design and optimization
A first phase in the habitat classification for the Zeeschelde: Bed form classification
Within the scope of the long term vision of the Schelde Estuary and the Development Outline 2010 low dynamic intertidal and shallow water areas are considered to be of high ecological value. Little is known about the occurrence of such valuable reas in the Schelde Estuary, nor are the physical and morphological processes which determine the occurrence of these areas fully understood. Based on the results and recommendations of a 2008-2009 research project in the Westerschelde, a new research project was defined to determine relationships between abiotic (bedforms, hydrodynamics, sediment) and biotic (benthos) characteristics in the Zeeschelde (Belgium) and to set up a classification of deep and undeep subtidal areas. A first phase in the habitat classification comprises of the analysis of bed form occurrence and the setup of a bed form classification based on multibeam echo sounding data. Results show within the different sub areas a variation in bed forms going from hard bed layers to no bed forms to ripples (H ~ 0,1 to 0,3 m | L ~ 10 m) and smaller dunes (H ~ 0,5 to 1 m | L ~ 15 to 25 m). On-going research investigates relationships between the bed form characteristics and flow and sediment characteristics. Preliminary results
What is known about deferasirox chelation therapy in pediatric HSCT recipients: two case reports of metabolic acidosis
To date, in pediatric field, various hematological malignancies are increasingly treated with allogeneic hematopoietic stem cell transplantation (allo-HSCT). Iron overload and systemic siderosis often occur in this particular cohort of patients and are associated with poor prognosis. We describe herein the case of two allo-HSCT patients, on treatment with deferasirox; they showed histopathological elements compatible with venoocclusive disease or vanishing bile duct syndrome in ductopenic evolution before deferasirox started. The first patient developed drug-induced liver damage with metabolic acidosis and the second one a liver impairment with Fanconi syndrome. After withdrawing deferasirox treatment, both patients showed improvement. Measurements of drug plasma concentrations were performed by HPLC assay. The reduction and consequent disappearance of symptoms after the suspension of deferasirox substantiate its role in inducing hepatic damage, probably enabling the diagnosis of drug-induced liver damage. But the difficulties in diagnosing drug-related toxicity must be underlined, especially in compromised subjects. For these reasons, in patients requiring iron-chelating therapy, close and careful drug therapeutic monitoring is strongly recommende
Suvremeni putokazi razvitka industrije cijevi
First the paper presents a review of steel production of the tubes in world: possible potencial is about 110 × 106 the tons (35 × 106 seamless tubes, rest welding tubes). In 2007. y. was record volume of 88,6 ×106 tons in world; 6,5% of total production of steel in world. Ratio-weldeds tubes: seamless tubes 70:30%. Further in the article are presented urgent the problems of the pipe and tube industry.Prvi dio članka daje pregled proizvodnje čeličnih cijevi u svijetu: moguća je proizvodnost 110 × 106 tona (35 × 106 tona bešavnih cijevi, ostatak šavne cijevi). U 2007. god. bila je rekordna proizvodnja cijevi u svijetu 88,6 × 106 tona, tj. 6,5% od ukupne proizvodnje čelika u svijetu. Odnos – šavne cijevi: bešavne cijevi 70:30%. U nastavku članka su navedeni žurni problemi u industriji cijevi
Generational features of ethnic personal identification in a MultiEthnic society
© 2018 Transilvanian Association for the Literarure and Culture of Romanian People (ASTRA). All rights reserved. The paper deals with the thesis about the generational factor's influence on personal identification in conditions of a multi-ethnic society. Based on input received through the representative survey held in the multi-ethnic and multi-confessional region of Russia - the Republic of Tatarstan, the authors recorded the enhanced relevance of ethnic identification in elder and younger generations and the absence of the sharp ethnic bias as well as religious intolerance in all generations. The study identified the following categories of intergenerational relationships: optimists, pessimists and fatalists. The analysis revealed the higher level of ethnic identity among the Tatar population of the region as compared with the Russian one. It was justified that in order to preserve inter-ethnic tolerance in a multi-ethnic society it is necessary to ensure social and cultural continuity of generations by promoting optimal combination of macro- and micro-social identifications of both traditional established forms and modernist, especially postmodernist types
Genetic variability and structure of SNP haplotypes in the DMPK gene in Yakuts and other ethnic groups of northern Eurasia in relation to myotonic dystrophy
The genetic variability of the DMPK locus has been studied in relation to six SNP markers (rs2070736, rs572634, rs1799894, rs527221, rs915915, and rs10415988) in Yakuts with myotonic dystrophy (MD) in the Yakut population and in populations of northern Eurasia. Significant differences were observed in the allele frequencies between patients and a population sample of Yakuts for three SNP loci (rs915915, rs1799894, and rs0415988) associated with a high chance of disease manifestation. The odds ratios (OR) of MD development in representatives of the Yakut population for these three loci were 2.59 (95% CI, p = 0,004), 4.99 (95% CI, p = 0.000), and 3.15 (95% CI, p = 0.01), respectively. Haplotype TTTCTC, which is associated with MD, and haplotype GTCCTT, which was observed only in Yakut MD patients (never in MD patients of non-Yakut origin), were revealed. A low level of variability in the locus of DMRK gene in Yakuts (He = 0.283) compared with other examined populations was noted. An analysis of pairwise genetic relationships between populations revealed their significant differentiation for all the examined loci. In addition, a low level of differentiation in territorial groups of Yakut populations (FST = 0.79%), which was related to the high subdivision of the northern Eurasian population (FST = 11.83%), was observed
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