Comparison of MEMS switches and PIN diodes for switched dual tuned RF coils

PURPOSE: To evaluate the performance of micro-electromechanical systems (MEMS) switches against PIN diodes for switching a dual-tuned RF coil between19F and1H resonant frequencies for multi-nuclear lung imaging. METHODS: A four-element fixed-phase and amplitude transmit-receive RF coil was constructed to provide homogeneous excitation across the lungs, and to serve as a test system for various switching methods. The MR imaging and RF performance of the coil when switched between the19F and1H frequencies using MEMS switches, PIN diodes and hardwired configurations were compared. RESULTS: The performance of the coil with MEMS or PIN diode switching was comparable in terms of RF measurements, transmit efficiency and image SNR on both19F and1H nuclei. When the coil was not switched to the resonance frequency of the respective nucleus being imaged, reductions in the transmit efficiency were observed of 32% at the19F frequency and 12% at the1H frequency. The coil provides transmit field homogeneity of ±12.9% at the1H frequency and ±14.4% at the19F frequency in phantoms representing the thorax with the air space of the lungs filled with perfluoropropane gas. CONCLUSION: MEMS and PIN diodes were found to provide comparable performance in on-state configuration, while MEMS were more robust in off-state high-powered operation (>1 kW), providing higher isolation and requiring a lower DC switching voltage than is needed for reverse biasing of PIN diodes. In addition, clear benefits of switching between the19F and1H resonances were demonstrated, despite the proximity of their Larmor frequencies

A solar cycle lost in 1793--1800: Early sunspot observations resolve the old mystery

Because of the lack of reliable sunspot observation, the quality of sunspot number series is poor in the late 18th century, leading to the abnormally long solar cycle (1784--1799) before the Dalton minimum. Using the newly recovered solar drawings by the 18--19th century observers Staudacher and Hamilton, we construct the solar butterfly diagram, i.e. the latitudinal distribution of sunspots in the 1790's. The sudden, systematic occurrence of sunspots at high solar latitudes in 1793--1796 unambiguously shows that a new cycle started in 1793, which was lost in traditional Wolf's sunspot series. This finally confirms the existence of the lost cycle that has been proposed earlier, thus resolving an old mystery. This letter brings the attention of the scientific community to the need of revising the sunspot series in the 18th century. The presence of a new short, asymmetric cycle implies changes and constraints to sunspot cycle statistics, solar activity predictions, solar dynamo theories as well as for solar-terrestrial relations.Comment: Published by Astrophys. J. Let

Enhanced Accessibility for People with Disabilities Living in Urban Areas

[Excerpt] People with disabilities constitute a significant proportion of the poor in developing countries. If internationally agreed targets on reducing poverty are to be reached, it is critical that specific measures be taken to reduce the societal discrimination and isolation that people with disabilities continue to face. Transport is an important enabler of strategies to fight poverty through enhancing access to education, employment, and social services. This project aims to further the understanding of the mobility and access issues experienced by people with disabilities in developing countries, and to identify specific steps that can be taken to start addressing problems. A major objective of the project is to compile a compendium of guidelines that can be used by government authorities, advocacy groups, and donor/loan agencies to improve the access of people with disabilities to transport and other services in urban areas

Invisible sunspots and rate of solar magnetic flux emergence

Aims. We study the visibility of sunspots and its influence on observed values of sunspot region parameters. Methods. We use Virtual Observatory tools provided by AstroGrid to analyse a sample of 6862 sunspot regions. By studying the distributions of locations where sunspots were first and last observed on the solar disk, we derive the visibility function of sunspots, the rate of magnetic flux emergence and the ratio between the durations of growth and decay phases of solar active regions. Results. We demonstrate that the visibility of small sunspots has a strong centre-to-limb variation, far larger than would be expected from geometrical (projection) effects. This results in a large number of young spots being invisible: 44% of new regions emerging in the west of the Sun go undetected. For sunspot regions that are detected, large differences exist between actual locations and times of flux emergence, and the apparent ones derived from sunspot data. The duration of the growth phase of solar regions has been, up to now, underestimated

Intranasal immunisation with recombinant adenovirus vaccines protects against a lethal 2 challenge with pneumonia virus of mice

Pneumonia virus of mice (PVM) infection of BALB/c mice induces bronchiolitis leading to a fatal pneumonia in a dose-dependent manner, closely paralleling the development of severe disease during human respiratory syncytial virus infection in man, and is thus a recognised model in which to study the pathogenesis of pneumoviruses. This model system was used to investigate delivery of the internal structural proteins of PVM as a potential vaccination strategy to protect against pneumovirus disease. Replication-deficient recombinant human adenovirus serotype 5 (rAd5) vectors were constructed that expressed the M or N gene of PVM pathogenic strain J3666. Intranasal delivery of these rAd5 vectors gave protection against a lethal challenge dose of PVM in three different mouse strains, and protection lasted for at least 20 weeks post-immunisation. Whilst the PVM-specific antibody response isuch animals was weak and inconsistent, rAd5N primed a strong PVM-specific CD8+ T cell response and, to a lesser extent, a CD4+ T cell response. These findings suggest that protection induced by rAd5N was mediated by T-cells rather than serum antibody

The phase relation between sunspot numbers and soft X-ray flares

To better understand long-term flare activity, we present a statistical study on soft X-ray flares from May 1976 to May 2008. It is found that the smoothed monthly peak fluxes of C-class, M-class, and X-class flares have a very noticeable time lag of 13, 8, and 8 months in cycle 21 respectively with respect to the smoothed monthly sunspot numbers. There is no time lag between the sunspot numbers and M-class flares in cycle 22. However, there is a one-month time lag for C-class flares and a one-month time lead for X-class flares with regard to sunspot numbers in cycle 22. For cycle 23, the smoothed monthly peak fluxes of C-class, M-class, and X-class flares have a very noticeable time lag of one month, 5 months, and 21 months respectively with respect to sunspot numbers. If we take the three types of flares together, the smoothed monthly peak fluxes of soft X-ray flares have a time lag of 9 months in cycle 21, no time lag in cycle 22 and a characteristic time lag of 5 months in cycle 23 with respect to the smoothed monthly sunspot numbers. Furthermore, the correlation coefficients of the smoothed monthly peak fluxes of M-class and X-class flares and the smoothed monthly sunspot numbers are higher in cycle 22 than those in cycles 21 and 23. The correlation coefficients between the three kinds of soft X-ray flares in cycle 22 are higher than those in cycles 21 and 23. These findings may be instructive in predicting C-class, M-class, and X-class flares regarding sunspot numbers in the next cycle and the physical processes of energy storage and dissipation in the corona.Comment: 8 pages, 3 figures, Accepted for publication in Astrophysics & Space Scienc

The National Food Consumption Survey (NFCS): South Africa, 1999

Objective: The aim of the National Food Consumption Survey (NFCS) in South Africa was to determine the nutrient intakes and anthropometric status of children (1-9 years old), as well as factors that influence their dietary intake. Design: This was a cross-sectional survey of a nationally representative sample of all children aged 1-9 years in South Africa. A nationally representative sample with provincial representation was selected using 1996 Census information. Subjects: Of the 3120 children who were originally sampled data were obtained from 2894, a response rate of 93%. Methods: The sociodemographic status of each household was assessed by a questionnaire. Dietary intake was assessed by means of a 24-hour recall and a food-frequency questionnaire from the caregivers of the children. Food purchasing practices were determined by means of a food procurement questionnaire. Hunger was assessed by a modified hunger scale questionnaire. Nutritional status was determined by means of anthropometric measurements: height, weight, head circumference and arm circumference. Results: At the national level, stunting (height-for-age below minus two standard deviations (< -2SD) from the reference median) was by far the most common nutritional disorder, affecting nearly one in five children. The children least affected (17%) were those living in urban areas. Even with regard to the latter, however, children living in informal urban areas were more severely affected (20%) compared with those living in formal urban areas (16%). A similar pattern emerged for the prevalence of underweight (weight-for-age < -2SD), with one in 10 children being affected at the national level. Furthermore, one in 10 (13%) and one in four (26%) children aged 1-3 years had an energy intake less than half and less than two-thirds of their daily energy needs, respectively. For South African children as a whole, the intakes of energy, calcium, iron, zinc, selenium, vitamins A, D, C and E, riboflavin, niacin, vitamin B6 and folic acid were below two-thirds of the Recommended Dietary Allowances. At the national level, data from the 24-hour recalls indicated that the most commonly consumed food items were maize, sugar, tea, whole milk and brown bread. For South African children overall, one in two households (52%) experienced hunger, one in four (23%) were at risk of hunger and only one in four households (25%) appeared food-secure. Conclusion: The NFCS indicated that a large majority of households were food-insecure and that energy deficit and micronutrient deficiencies were common, resulting in a high prevalence of stunting. These results were used as motivation for the introduction of mandatory fortification in South Africa. © The Authors 2005.Conference Pape

A left-handed simplicial action for euclidean general relativity

An action for simplicial euclidean general relativity involving only left-handed fields is presented. The simplicial theory is shown to converge to continuum general relativity in the Plebanski formulation as the simplicial complex is refined. This contrasts with the Regge model for which Miller and Brewin have shown that the full field equations are much more restrictive than Einstein's in the continuum limit. The action and field equations of the proposed model are also significantly simpler then those of the Regge model when written directly in terms of their fundamental variables. An entirely analogous hypercubic lattice theory, which approximates Plebanski's form of general relativity is also presented.Comment: Version 3. Adds current home address + slight corrections to references of version 2. Version 2 = substantially clarified form of version 1. 29 pages, 4 figures, Latex, uses psfig.sty to insert postscript figures. psfig.sty included in mailing, also available from this archiv