Survey of prescription medication disposal practices in older patients

The purpose of the proposed study was to survey participants on current medication disposal practices, and to gather preliminary data on the types of medications found in the home environment

Supervisor Cultural Responsiveness and Unresponsiveness in Cross-Cultural Supervision

Thirteen supervisees’ of color and 13 European American supervisees’ experiences of culturally responsive and unresponsive cross-cultural supervision were studied using consensual qualitative research. In culturally responsive supervision, all supervisees felt supported for exploring cultural issues, which positively affected the supervisee, the supervision relationship, and client outcomes. In culturally unresponsive supervision, cultural issues were ignored, actively discounted, or dismissed by supervisors, which negatively affected the supervisee, the relationship, and/or client outcomes. European American supervisees’ and supervisees’ of color experiences diverged significantly, with supervisees of color experiencing unresponsiveness more frequently and with more negative effects than European American supervisees. Implications for research and supervision practice are discussed

Measuring Client Experiences of Motivational Interviewing During a Lifestyle Intervention

The Client Evaluation of Motivational Interviewing was used to assess motivational interviewing experiences in a predominantly female, African American sample from the Southeastern United States who received motivational interviewing-based feedback during a multicomponent lifestyle intervention. Motivational interviewing was experienced differently than a primarily White, male, Northeastern mental health sample

Training MI Interventionists across Disciplines: A Descriptive Project

Motivational Interviewing (MI) is a counseling approach that is versatile and can be applied in many professional settings. Therefore, teaching MI skills to multidisciplinary groups simultaneously has the potential to be quite beneficial for strengthening the MI skills of different groups. This paper describes a project in which professionals and students from psychology and nutrition/ dietetics were trained in MI in an attempt to bolster both groups’ ability to implement MI as part of a larger health intervention project. Specifically, we outline the common themes that emerged among the trainees’ experiences. Implementing a multidisciplinary training program in which trainees use their expertise and contribute to the training process appeared to have created a rich learning environment.

Vermicompost as a natural adsorbent material: characterization and potentialities for cadmium adsorption

Vermicompost (humic material) samples were submitted to characterization by infrared spectroscopy, X-ray diffractometry, thermogravimetric analysis, electron microscopy etc. In addition, its cation exchange capacity (CEC) was determined. Factorial experiments were designed in order to elucidate the interaction mechanisms between Cd2+ and the adsorptive sites of vermicompost. The maximum adsorptive capacity for cadmium was evaluated by a Langmuir isotherm. The characterization revealed that vermicompost exhibits high CEC values (ca. 72.9 meq per 100 g), high surface area (porous material), chelating groups and a maximum adsorptive capacity for Cd (38.6 mg g-1) at pH 5.0. This potential application was exploited in the analysis of synthetic and real (mineral water) samples with Cd concentrations of ca 5 mug L-1, requiring a preconcentration step. An enrichment factor of 100 was attained.Amostras de vermicomposto (material húmico) foram submetidas à caracterização por espectroscopia de infravermelho, difractometria de raios-X, termogravimetria, microscopia eletrônica, entre outras; adicionalmente, foi determinada a capacidade de troca catiônica (CTC). Empregou-se planejamento fatorial para estudar os mecanismos de interação da espécie Cd2+ com os sítios adsortivos do vermicomposto e, posteriormente, foi avaliada a máxima capacidade adsortiva de cádmio empregando isoterma de Langmuir. A caracterização revelou que o vermicomposto exibe CTC tão elevada quanto 72,9 meq por 100 g, grande área superficial (substância porosa), grupos quelantes e máxima capacidade adsortiva para Cd (38,6 mg g-1) em pH 5,0. Esta potencialidade foi explorada em análises de amostras sintéticas e reais (água mineral) apresentando concentrações de cádmio próximas a 5 mig L-1 e requerendo etapas de pré-concentração. Um fator de enriquecimento de 100 foi obtido.3947Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

Effects of Label Dose Permethrin Use in Yearling Angus Beef Bulls on Reproductive Function and Testicular Histopathology

To eliminate the potential for insect borne diseases and improve productivity in cow-calf operations, many producers use pour-on pyrethroids. However, popular press literature has identified potential links between use of pyrethroids and reproductive function failures in bulls. While literature in mice and rats have reported potential endocrine disruption of sex steroids resulting from pyrethroid exposure, effects of pyrethroid use on bull fertility is still questionable. The objective of this study was to measure reproductive parameters in peripubertal Angus bulls using a commonly used pyrethroid pour-on. We hypothesized that use of a pyrethroid pour-on at labeled dose would have limited effects on semen and testicular characteristics. Results from this study revealed pyrethroid-treated bulls had greater spermatozoa head and midpiece abnormalities compared to controls, resulting in higher primary morphological abnormalities. Although some morphological semen parameters appear to be negatively affected by use of pyrethroid administration in bulls, biological relevance of this result needs to be further elucidated as the ability to pass a breeding soundness exam was not affected. Moreover, further research should be conducted to determine the effects of pyrethroid pour-ons on fertility when used with other pyrethroids such fly tags or perimeter sprays. Based on these results, pour-on pyrethroid use in yearling bulls is still recommended for label dose administration

Role of obesity in a randomized placebo-controlled trial of difluoromethylornithine (DFMO) + sulindac for the prevention of sporadic colorectal adenomas.

BackgroundChemoprevention with the polyamine-inhibitory regimen difluoromethylornithine (DFMO) + sulindac markedly reduces risk of recurrent adenoma in colorectal adenoma patients. Obesity is associated with risk of colorectal adenoma and colorectal cancer. This study investigates how obesity influences risk of recurrent adenoma after prolonged treatment with DFMO + sulindac versus placebo.MethodsOur analysis included subjects enrolled in the phase III colorectal adenoma prevention clinical trial investigating DFMO + sulindac versus placebo. Patients were classified by obesity (body mass index, BMI ≥ 30 kg/m(2)) status at baseline. Pearson χ(2) statistic and Mann-Whitney U test were used to compare baseline characteristics, including rectal tissue polyamine levels. Log-binomial regression analysis was used to determine the risk ratio (RR) of recurrent adenomas, adjusted for covariates and an interaction term for obesity and treatment.ResultsThe final analytic cohort was comprised of 267 patients. In separate regression models, the risk of adenoma recurrence after treatment compared to placebo was similar for obese (RR = 0.32, 95 % CI 15-71) and non-obese patients (RR = 0.27, 95 % CI 15-49). No significant interaction was detected between obesity, treatment, and risk of colorectal adenoma in the full regression model (p (interaction) = 0.91).ConclusionsObesity does not substantially modify the colorectal adenoma risk reduction ascribed to DFMO + sulindac versus placebo

Sonic boom prediction and minimization using computational fluid dynamics

This paper describes the NASA ARC program in sonic boom prediction methodologies. This activity supports NASA's High Speed Research Program (HSRP). An overview of the program, recent results, conclusions, and current effort will be given. This effort complements research in sonic boom acceptability and validation being conducted at LaRC and ARC. The goals of the sonic boom element are as follows: to establish a predictive capability for sonic booms generated by High-Speed Civil Transport (HSCT) concepts; to establish guidelines of acceptability for supersonic overland flight; and to validate these findings with wind tunnel and flight tests. The cumulative result of these efforts will be an assessment of economic viability for supersonic transportation. This determination will ultimately be made by the aerospace industry