400 research outputs found
Strongly residual coordinates over A[x]
For a domain A of characteristic zero, a polynomial f over A[x] is called a
strongly residual coordinate if f becomes a coordinate (over A) upon going
modulo x, and f becomes a coordinate upon inverting x. We study the question of
when a strongly residual coordinate is a coordinate, a question closely related
to the Dolgachev-Weisfeiler conjecture. It is known that all strongly residual
coordinates are coordinates for n=2 . We show that a large class of strongly
residual coordinates that are generated by elementaries upon inverting x are in
fact coordinates for arbitrary n, with a stronger result in the n=3 case. As an
application, we show that all Venereau-type polynomials are 1-stable
coordinates.Comment: 15 pages. Some minor clarifications and notational improvements from
the first versio
Roots of the affine Cremona group
Let k[x_1,...,x_n] be the polynomial algebra in n variables and let A^n=Spec
k[x_1,...,x_n]. In this note we show that the root vectors of the affine
Cremona group Aut(A^n) with respect to the diagonal torus are exactly the
locally nilpotent derivations x^a\times d/dx_i, where x^a is any monomial not
depending on x_i. This answers a question due to Popov.Comment: 4 page
On Proper Polynomial Maps of
Two proper polynomial maps are said to be \emph{equivalent} if there exist such that .
We investigate proper polynomial maps of arbitrary topological degree up to equivalence. Under the further assumption that the maps are Galois
coverings we also provide the complete description of equivalence classes. This
widely extends previous results obtained by Lamy in the case .Comment: 15 pages. Final version, to appear in Journal of Geometric Analysi
Regulated Expression of Human Histocompatibility Leukocyte Antigen (HLA)-DO During Antigen-dependent and Antigen-independent Phases of B Cell Development
Human histocompatibility leukocyte antigen (HLA)-DO, a lysosomal resident major histocompatibility complex class II molecule expressed in B cells, has previously been shown to be a negative regulator of HLA-DM peptide loading function. We analyze the expression of DO in human peripheral blood, lymph node, tonsil, and bone marrow to determine if DO expression is modulated in the physiological setting. B cells, but not monocytes or monocyte-derived dendritic cells, are observed to express this protein. Preclearing experiments demonstrate that ∼50% of HLA-DM is bound to DO in peripheral blood B cells. HLA-DM and HLA-DR expression is demonstrated early in B cell development, beginning at the pro-B stage in adult human bone marrow. In contrast, DO expression is initiated only after B cell development is complete. In all situations, there is a striking correlation between intracellular DO expression and cell surface class II–associated invariant chain peptide expression, which suggests that DO substantially inhibits DM function in primary human B cells. We report that the expression of DO is markedly downmodulated in human germinal center B cells. Modulation of DO expression may provide a mechanism to regulate peptide loading activity and antigen presentation by B cells during the development of humoral immune responses
Evidence of two viscous relaxation processes in the collective dynamics of liquid lithium
New inelastic X-ray scattering experiments have been performed on liquid
lithium in a wide wavevector range. With respect to the previous measurements,
the instrumental resolution, improved up to 1.5 meV, allows to accurately
investigate the dynamical processes determining the observed shape of the the
dynamic structure factor, . A detailed analysis of the lineshapes
shows the co-existence of relaxation processes with both a slow and a fast
characteristic timescales, and therefore that pictures of the relaxation
mechanisms based on a simple viscoelastic model must be abandoned.Comment: 5 pages, 4 .PS figure
Evidence of short time dynamical correlations in simple liquids
We report a molecular dynamics (MD) study of the collective dynamics of a
simple monatomic liquid -interacting through a two body potential that mimics
that of lithium- across the liquid-glass transition. In the glassy phase we
find evidences of a fast relaxation process similar to that recently found in
Lennard-Jones glasses. The origin of this process is ascribed to the
topological disorder, i.e. to the dephasing of the different momentum
Fourier components of the actual normal modes of vibration of the disordered
structure. More important, we find that the fast relaxation persists in the
liquid phase with almost no temperature dependence of its characteristic
parameters (strength and relaxation time). We conclude, therefore, that in the
liquid phase well above the melting point, at variance with the usual
assumption of {\it un-correlated} binary collisions, the short time particles
motion is strongly {\it correlated} and can be described via a normal mode
expansion of the atomic dynamics.Comment: 7 pages, 7 .eps figs. To appear in Phys. Rev.
Inelastic X-ray scattering study of the collective dynamics in liquid sodium
Inelastic X-ray scattering data have been collected for liquid sodium at
T=390 K, i.e. slightly above the melting point. Owing to the very high
instrumental resolution, pushed up to 1.5 meV, it has been possible to
determine accurately the dynamic structure factor, , in a wide
wavevector range, nm, and to investigate on the dynamical
processes underlying the collective dynamics. A detailed analysis of the
lineshape of , similarly to other liquid metals, reveals the
co-existence of two different relaxation processes with slow and fast
characteristic timescales respectively. The present data lead to the conclusion
that: i) the picture of the relaxation mechanism based on a simple viscoelastic
model fails; ii) although the comparison with other liquid metals reveals
similar behavior, the data do not exhibit an exact scaling law as the principle
of corresponding state would predict.Comment: RevTex, 7 pages, 6 eps figures. Accepted by Phys. Rev.
Dynamical properties of liquid Al near melting. An orbital-free molecular dynamics study
The static and dynamic structure of liquid Al is studied using the orbital
free ab-initio molecular dynamics method. Two thermodynamic states along the
coexistence line are considered, namely T = 943 K and 1323 K for which X-ray
and neutron scattering data are available. A new kinetic energy functional,
which fulfills a number of physically relevant conditions is employed, along
with a local first principles pseudopotential. In addition to a comparison with
experiment, we also compare our ab-initio results with those obtained from
conventional molecular dynamics simulations using effective interionic pair
potentials derived from second order pseudopotential perturbation theory.Comment: 15 pages, 12 figures, 2 tables, submitted to PR
Geography-dependent horizontal gene transfer from vertebrate predators to their prey
Horizontal transfer (HT) of genes between multicellular animals, once thought to be extremely rare, is being more commonly detected, but its global geographic trend and transfer mechanism have not been investigated. We discovered a unique HT pattern of Bovine-B (BovB) LINE retrotransposons in vertebrates, with a bizarre transfer direction from predators (snakes) to their prey (frogs). At least 54 instances of BovB HT were detected, which we estimate to have occurred across time between 85 and 1.3 Ma. Using comprehensive transcontinental sampling, our study demonstrates that BovB HT is highly prevalent in one geographical region, Madagascar, suggesting important regional differences in the occurrence of HTs. We discovered parasite vectors that may plausibly transmit BovB and found that the proportion of BovB-positive parasites is also high in Madagascar where BovB thus might be physically transported by parasites to diverse vertebrates, potentially including humans. Remarkably, in two frog lineages, BovB HT occurred after migration from a non-HT area (Africa) to the HT hotspot (Madagascar). These results provide a novel perspective on how the prevalence of parasites influences the occurrence of HT in a region, similar to pathogens and their vectors in some endemic diseases
Bis(μ-4-phenylpyridine N-oxide-κ2 O:O)bis[bis(1,1,1,5,5,5-hexafluoropentane-2,4-dionato)copper(II)]
The asymmetric unit of the title compound, [Cu2(C5HF6O2)4(C11H9NO)2], contains one half of the centrosymmetric dinuclear complex. The coordination geometry of the CuII atom is octahedral, exhibiting a typical Jahn–Teller distortion. One trifluoromethyl group is rotationally disordered between two orientations in a 1:1 ratio
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