The determination of the direction of the optic axis of uniaxial crystalline materials

The birefringence of crystalline substances in general, and of sapphire in particular, is described. A test is described whose purpose is to determine the direction of the optic axis of a cylindrically machined single crystal of sapphire. This test was performed on the NASA Lewis sapphire cylinder and it was found that the optic axis made an angle of 18 deg with the axis of symmetry of the cylinder

Electron beam-induced current imaging with two-angstrom resolution.

An electron microscope's primary beam simultaneously ejects secondary electrons (SEs) from the sample and generates electron beam-induced currents (EBICs) in the sample. Both signals can be captured and digitized to produce images. The off-sample Everhart-Thornley detectors that are common in scanning electron microscopes (SEMs) can detect SEs with low noise and high bandwidth. However, the transimpedance amplifiers appropriate for detecting EBICs do not have such good performance, which makes accessing the benefits of EBIC imaging at high-resolution relatively more challenging. Here we report lattice-resolution imaging via detection of the EBIC produced by SE emission (SEEBIC). We use an aberration-corrected scanning transmission electron microscope (STEM), and image both microfabricated devices and standard calibration grids

Magsat: A satellite for measuring near earth magnetic fields

Magsat, designed for making measurements of the geomagnetic vector field, is evaluated. For accurate vector measurements the attitude of the fluxgate magnetometer will be determined to about 15 arc-seconds. Expected measurement accuracy will be 6 (gamma) in each component and 3 in magnitude. The Magsat data will be applied to solid earth studies including modeling of the Earth's main magnetic field, delineation of regional magnetic anomalies of crustal origin, and interpretation of those anomalies in terms of geologic and geophysical models. An opportunity will be presented to the scientific community to participate in data use investigations

The suppression of superconductivity in MgCNi3 by Ni-site doping

The effects of partial substitution of Cu and Co for Ni in the intermetallic perovskite superconductor MgCNi3 are reported. Calculation of the expected electronic density of states suggests that electron (Cu) and hole (Co) doping should have different effects. For MgCNi3-xCux, solubility of Cu is limited to approximately 3% (x = 0.1), and Tc decreases systematically from 7K to 6K. For MgCNi3-xCox, solubility of Co is much more extensive, but bulk superconductivity disappears for Co doping of 1% (x = 0.03). No signature of long range magnetic ordering is observed in the magnetic susceptibility of the Co doped material.Comment: submitted, Solid State Communication

Rapid and efficient stable gene transfer to mesenchymal stromal cells using a modified foamy virus vector

Mesenchymal stromal cells (MSCs) hold great promise for regenerative medicine. Stable ex vivo gene transfer to MSCs could improve the outcome and scope of MSC therapy, but current vectors require multiple rounds of transduction, involve genotoxic viral promoters and/or the addition of cytotoxic cationic polymers in order to achieve efficient transduction. We describe a self-inactivating foamy virus vector (FVV), incorporating the simian macaque foamy virus envelope and using physiological promoters, which efficiently transduces murine MSCs (mMSCs) in a single-round. High and sustained expression of the transgene, whether GFP or the lysosomal enzyme, arylsulphatase A (ARSA), was achieved. Defining MSC characteristics (surface marker expression and differentiation potential), as well as long-term engraftment and distribution in the murine brain following intracerebroventricular delivery, are unaffected by FVV transduction. Similarly, greater than 95% of human MSCs (hMSCs) were stably transduced using the same vector, facilitating human application. This work describes the best stable gene transfer vector available for mMSCs and hMSCs

The Vortex Phase Diagram of Rotating Superfluid 3^3He-B

We present the first theoretical calculation of the pressure-temperature-field phase diagram for the vortex phases of rotating superfluid $^3$He-B. Based on a strong-coupling extension of the Ginzburg-Landau theory that accounts for the relative stability of the bulk A and B phases of $^3$He at all pressures, we report calculations for the internal structure and free energies of distinct broken-symmetry vortices in rotating superfluid $^3$He-B. Theoretical results for the equilibrium vortex phase diagram in zero field and an external field of H=284\,\mbox{G} parallel to the rotation axis, $\vec{H}\parallel\vec{\Omega}$, are reported, as well as the supercooling transition line, $T^{*}_ {v} (p,H)$. In zero field the vortex phases of $^3$He-B are separated by a first-order phase transition line $T_ {v} (p)$ that terminates on the bulk critical line $T_{c}(p)$ at a triple point. The low-pressure, low-temperature phase is characterized by an array of singly-quantized vortices that spontaneously breaks axial rotation symmetry, exhibits anisotropic vortex currents and an axial current anomaly (D-core phase). The high-pressure, high-temperature phase is characterized by vortices with both bulk A phase and $\beta$ phase in their cores (A-core phase). We show that this phase is metastable and supercools down to a minimum temperature, $T^{*}_ {v} (p,H)$, below which it is globally unstable to an array of D-core vortices. For H\gtrsim 60\,\mbox{G} external magnetic fields aligned along the axis of rotation increase the region of stability of the A-core phase of rotating $^3$He-B, opening a window of stability down to low pressures. These results are compared with the experimentally reported phase transitions in rotating $^3$He-B.Comment: 14 pages, 11 figure

Surface Structure of Liquid Metals and the Effect of Capillary Waves: X-ray Studies on Liquid Indium

We report x-ray reflectivity (XR) and small angle off-specular diffuse scattering (DS) measurements from the surface of liquid Indium close to its melting point of $156^\circ$C. From the XR measurements we extract the surface structure factor convolved with fluctuations in the height of the liquid surface. We present a model to describe DS that takes into account the surface structure factor, thermally excited capillary waves and the experimental resolution. The experimentally determined DS follows this model with no adjustable parameters, allowing the surface structure factor to be deconvolved from the thermally excited height fluctuations. The resulting local electron density profile displays exponentially decaying surface induced layering similar to that previously reported for Ga and Hg. We compare the details of the local electron density profiles of liquid In, which is a nearly free electron metal, and liquid Ga, which is considerably more covalent and shows directional bonding in the melt. The oscillatory density profiles have comparable amplitudes in both metals, but surface layering decays over a length scale of $3.5\pm 0.6$ \AA for In and $5.5\pm 0.4$ \AA for Ga. Upon controlled exposure to oxygen, no oxide monolayer is formed on the liquid In surface, unlike the passivating film formed on liquid Gallium.Comment: 9 pages, 5 figures; submitted to Phys. Rev.