Indoor air quality and early detection of mould growth in residential buildings: a case study

Mould growth affects one in three homes, and it is the biggest cause for complaints and litigations filed to the relevant authorities in Australia, while also significantly affecting the physical and psychological health of the building’s occupants. Indoor mould is caused by excessive dampness, resulting from poor architectural specification, construction and maintenance practices, as well as inappropriate behaviour of the occupants. The consequences range from early biodeterioration of building materials, requiring anticipated renovation works, to deterioration of the indoor environment, posing a serious threat to the building’s occupants. This study investigates indoor air quality (IAQ) and mould growth, providing a snapshot of the current IAQ of Australian residential buildings regarding air pollutants. It uses a case study representative of the typical Australian suburban home to investigate the effects of unnoticed mould growth. The results of the monitoring campaign indicate that buildings with a high concentration of fungal spores are also more likely to present poor IAQ levels, high concentrations of particulate matters (PM10 and PM2.5) and carbon dioxide (CO2). This research suggests the need for the development of early detection strategies that could minimise the health hazard to people, thereby preventing the need for any major renovations

The potential of harnessing real-time occupancy data for improving energy performance of activity-based workplaces

Currently, the available studies on the prediction of building energy performance and real occupancy data are typically characterized by aggregated and averaged occupancy patterns or large thermal zones of reference. Despite the increasing diffusion of smart energy management systems and the growing availability of longitudinal data regarding occupancy, these two domains rarely inform each other. This research aims at understanding the potential of employing real-time occupancy data to identify better cooling strategies for activity-based-working (ABW)-supportive offices and reduce the overall energy consumption. It presents a case study comparing the energy performance of the office when different resolutions of occupancy and thermal zoning are applied, ranging from the standard energy certification approach to real-time occupancy patterns. For the first time, one year of real-time occupancy data at the desk resolution, captured through computer logs and Bluetooth devices, is used to investigate this issue. Results show that the actual cooling demand is 9% lower than predicted, unveiling the energy-saving potential to be achieved from HVAC systems for non-assigned seating environments. This research demonstrates that harnessing real-time occupancy data for demand-supply cooling management at a fine-grid resolution is an efficient strategy to reduce cooling consumption and increase workers’ comfort. It also emphasizes the need for more data and monitoring campaigns for the definition of more accurate and robust energy management strategies

Development of an urban health and wellbeing index for work precincts: A comparative study in Sydney, Australia

Work precincts are recognized for their significant role as generators of employment and associated commerce within urban areas. This study describes a method for analyzing the physical characteristics of urban work precincts in promoting the health and wellbeing of their occupants. The following physical parameters are analyzed: public transport accessibility, green and blue spaces, food environments, fitness facilities, supermarkets, and grocery stores. The parameters are assessed using quantitative spatial analysis based on street network data, as well as point of interest data acquired from OpenStreetMap (OSM). The streets and their intersections are stored in the OSM database as links and nodes, respectively. The evaluation of the performance metrics involves measuring the street network distance from each node to the closest node of interest for each parameter. The metrics are then combined, forming an urban health and wellbeing index (UHWI), which can be used to compare the performance of different precincts. The method was tested by investigating four work precincts in Sydney, Australia, all hosting a large office building belonging to the same business institution. Our results identified two of the four precincts with a high UHWI and resulted in the identification of one underperforming precinct

Overlaps in space utilisation patterns and IEQ conditions observed in Activity-Based Working supportive office

One of the potential positive aspects of spaces designed to support Activity-Based Working (ABW) concept is to allow people to choose to work from zones that suit their Indoor Environmental Quality (IEQ) preferences. The vast majority of studies reporting findings relevant to IEQ performance of ABW spaces rely on spot measurements and/or subjective surveys and as such it is difficult to map longitudinal actual utilisation patterns and IEQ performance. This study contributes to this topic by analyzing a longitudinal dataset of space utilisation of an ABW over a twelve-month period. Analysis aims to identify overlaps between space utilisation patterns and expected IEQ performance in order to understand which types of zones occupants seem to prefer to work from. Occupants’ demographics (age and gender) were also analyzed with respect to the use of space. Further, specific physical markers were investigated, namely proximity to window, air-conditioning outlets, and high-low noise locations. The impact of physical markers on workplace choice was classified and predicted during a day using a decision-tree diagram developed on the basis of the CHAID algorithm. Overall, workers tended to choose to work within the inner zones (after 11 a.m.) during winter. Findings show that female workers moved away from air-conditioning outlets. Additionally, female workers worked from workstations situated in high and medium noise zones. Results illustrated the potential to use utilisation datasets to understand how workers move away or towards zones in response to expected IEQ performance - thermal comfort (cold/warm), acoustics (noisy/quiet), and access to the outdoor environment/view (window) proximity

Intracranial arterial aneurysm complicating Behcet's disease

WOS: A1996UM20900010PubMed ID: 8738367Behcet's disease, a rare condition in central Europe but more common in Turkey where it was originally described, is characterized clinically by the presence of a diagnostic triad of oral and genital aphthous ulcers, meningitis, and relapsing iridocyclitis. Vascularlesions including arterial and venous occlusions, arterial aneurysms and varices are one of the common complications of Behcet's disease occur most commonly in the abdominal aorta, femoral arteries and pulmonary arteries. There have been only four reports of aneurysms of cerebral arteries in the literature. The authors describe a patient with Behcet's disease who suffered secondary subarachnoid hemorrhage due to a ruptured aneurysm of the anterior communicating artery 3 years after the initial diagnosis. This case report draws further attention to this rare entity in patients with Behcet's disease

Synthesis and characterization of novel substituted thiophene derivatives and discovery of their carbonic anhydrase and acetylcholinesterase inhibition effects

Novel substituted thiophene derivatives (1, 2a-e, 3, and 4) were synthesized and their structures were characterized by infrared radiation, nuclear magnetic resonance, and mass analysis. These novel substituted thiophene derivatives were effective inhibitor compounds of the carbonic anhydrase I and II isozymes (hCA I and II), and acetylcholinesterase (AChE) enzyme with K-i values in the range of 447.28 to 1004.65 nM for hCA I, 309.44 to 935.93 nM for hCA II, and 0.28 to 4.01 nM for AChE, respectively. Novel substituted thiophene derivatives can be good candidate drugs for the treatment of some diseases like neurological disorders, epilepsy, glaucoma, gastric and duodenal ulcers, mountain sickness, or osteoporosis as carbonic anhydrase isozymes inhibitors, and for the treatment of Alzheimer's and Parkinson's diseases as acetylcholinesterase inhibitors

An unusual complication of the ventriculo-peritoneal shunt: Migration of the distal end into the scrotum through the inguinal canal

[No abstract available