155 research outputs found
Sensitivity of peatland carbon loss to organic matter quality
Copyright © 2012. American Geophysical Union. All Rights Reserved.This is the published version of the article; Leifeld, J., M. Steffens, and A. Galego-Sala (2012), Sensitivity of peatland carbon loss to organic matter quality, Geophys. Res. Lett., 39, L14704, doi:10.1029/2012GL051856.Peatland soils store substantial amounts of organic matter (OM). During peat formation, easily decomposable OM is preferentially lost and more recalcitrant moieties accumulate. In a peat profile, OM quality thus scales with depth. Drainage and ongoing climate change poses the risk of rapid OM loss when formerly anoxic peat layers oxidize. During peat decomposition, deeper, more recalcitrant peat is exposed to the oxygen-rich surface, which may influence the decomposition rate. We show that the soil respiration rate of a disturbed temperate peatland is strongly controlled by the peat's quality and especially its polysaccharides content. The polysaccharide content of soil profiles in a wider range of peatland sites with differing degrees of disturbance was inferred by means of solid-state13C NMR and DRIFT spectroscopy. The data confirmed a strong decline in polysaccharide content with depth and a poor OM quality of surface peat in soils drained decades ago. We combined the evidence from respiration and spectroscopic measurements to deduce the sensitivity of peatland carbon loss with respect to OM quality by scaling measured quality to a 142-years record of peatland subsidence and carbon loss at one of the sites. According to the functional relationship between quality and respiration, the measured average annual carbon loss rate of 2.5 t C ha−1 at that site was 20 t C ha−1 at the onset of peatland drainage and dropped to less than 1 t C ha−1 in recent times
To be or not to be hospitalised with tuberculosis in Portugal
SETTING: In Portugal, as in other countries, tuberculosis (TB) is considered a disease that should be managed on an ambulatory basis. However, hospitalisation remains important to manage some at-risk groups and complications.
OBJECTIVE: To identify the possible risk factors associated with hospitalisations in TB patients in Portugal.
DESIGN: Data extraction through two national databases (one for registration of TB cases and the other with hospitalisation information in public health facilities) between 2007 and 2013. Univariate and multivariate analysis of demographic and clinical variables was performed.
RESULTS: We identified 4421 hospitalisations. Chronic diseases, cancer, substance abuse, a higher social/economic risk, extra-pulmonary TB, lung cavitary disease and previous uncompleted treatment were more frequent among hospitalised patients. Human immunodeficiency virus coinfection, cancer, alcohol abuse, extra-pulmonary TB and uncompleted previous TB treatment were the most important predictors of hospitalisation with TB. The hospitalisation rate among TB patients in Portugal was lower when compared with other countries with lower and higher incidences.
CONCLUSION: Immune dysfunctions and progression of chronic diseases are associated with more severe forms of TB and frequent adverse effects which can be sufficiently severe to necessitate hospital admission. Despite having an intermediate TB incidence, the hospitalisation rate in Portugal is not higher than that of other countries
Evaluación, Cuidado y Registro Sistemático del Dolor
Artigo resultante de uma comunicação oral no I Congreso Iberoamericano sobre Dolor y Sufrimiento del Niño y su Familia, em que obteve o primeiro prémio.Evaluar el dolor es un desafío para los profesionales de salud. En Portugal, el dolor, fue elevado a la categoría de 5ª constante vital en 2003.
En el Hospital Mª Pia estamos implementando un proyecto de mejoría continua de la calidad sobre evaluación, cuidado y registro del dolor.
En la fase conceptual escogemos diversas escalas ya validadas para pediatria, definimos objetivos, indicadores de calidad y actividades para el desarrollo del proyecto. Como estrategia de base se proponen oportunidades de participación para todos los enfermeros.
La fase de implementación empezó con un cuestionario diagnostico que permitió sensibilizar los enfermeros para la temática del dolor, auscultar conocimientos y servir de referencia para programar la formación. Se ha hecho formación de soporte al desenvolvimiento del proyecto: escalas escogidas, elaboración de procedimientos técnicos de enfermería y dossier. La evaluación sistematizada del dolor a los niños ingresados en el hospital empezó, oficialmente, el día 6 de Setiembre de 2007.
Las dificultades notadas pasan por la necesidad de motivar continuamente a los enfermeros a una participación activa e reflejada; objetivar la evaluación del dolor en las situaciones más difíciles: niños/recién nacidos con ventilación mecánica y sedación bien como adolescentes emocionalmente inestables, ingresados en la pedopsiquiatria.
Estamos ahora en fase de auditorías y reformulación del proyecto para el prójimo año. Esperamos entrar en una fase de consolidación por lo que invertiremos en la formación específica del dolor y seguiremos creando oportunidades de participación.
Esperamos que en un futuro prójimo, el hospital tenga todos sus niños sin dolor
Downbeat Nystagmus in Episodic Ataxia Type 1 Associated with a Novel KCNA1 Mutation
info:eu-repo/semantics/publishedVersio
Nocturnal Blood Pressure Dipping in Acute Ischemic Stroke
OBJECTIVES:
We aim to assess the impact of early nocturnal blood pressure (BP) variation in the functional outcome of patients after an acute ischemic stroke.
MATERIALS AND METHODS:
We included consecutive stroke patients treated with intravenous thrombolysis (IVrtPA) in a tertiary stroke center. BP measurements were performed at regular intervals throughout day and night during the first 48 h after stroke onset, and subjects were divided into four dipping categories (extreme dippers, dippers, non-dippers, and reverse dippers). Recanalization was assessed by transcranial color-coded Doppler and/or angiographic CT. Hemorrhagic transformation was evaluated at 24 h follow-up CT scan. Functional outcome was evaluated at 3 months after stroke using the modified Rankin Scale.
RESULTS:
A total of 304 patients were included, mean age 72.80 ± 11.10 years. After 24 h of systolic BP monitoring, 30.59% were classified as reverse dippers, 39.14% as non-dippers, 19.10% as dippers, and 11.18% as extreme dippers. Multivariate analysis did not show an independent association of any dipping class with 3-month functional outcome. Hemorrhagic transformation was not uniform between dipping classes: 25.81% for reverse dippers, 14.29% for non-dippers, 15.52% for dippers, and 5.88% for extreme dippers, P = 0.033.
CONCLUSIONS:
Nocturnal BP dipping pattern is not associated with functional outcome at 3 months in acute stroke patients treated with IVrtPA. Hemorrhagic transformation was more frequent in reverse dippers.info:eu-repo/semantics/publishedVersio
Cognitive Impairment and Magnetic Resonance Imaging Correlates in Primary Progressive Multiple Sclerosis
Objectives: To characterize cognitive impairment in primary progressive multiple sclerosis (PPMS) and to correlate the pattern of cognitive deficits with brain magnetic resonance imaging (MRI) volumetric data.
Materials and methods: In a multicenter cross-sectional study, we recruited consecutive patients with PPMS as well as age, sex, and education level-matched healthy controls (HC). All participants underwent neuropsychological (NP) assessment, and brain MRI was performed in patients with PPMS for analysis of lesion load, subcortical GM volumes, and regional cortical volumes.
Results: We recruited 55 patients with PPMS and 36 HC. Thirty-six patients were included in the MRI analysis. Patients with PPMS performed significantly worse than HC in all NP tests. Subcortical GM volume was significantly correlated with all NP tests, except for Stroop Test, with the largest effect for the thalamus (r=-.516 [BVMT-R DR, P=.016 FDR-corrected] to r=.664 [SDMT, P<.001 FDR-corrected]). In the stepwise linear regression model, thalamic volume was the only predictor of performance in all NP tests.
Conclusion: Cognitive impairment is common in PPMS and affects all evaluated cognitive domains. Subcortical GM volume, particularly of the thalamus, is a strong predictor of cognitive performance, suggesting it has a central role in the pathophysiology of PPMS-related cognitive dysfunction.info:eu-repo/semantics/publishedVersio
Scenario of the spread of the invasive species Zaprionus indianus Gupta, 1970 (Diptera, Drosophilidae) in Brazil
Zaprionus indianus was first recorded in Brazil in 1999 and rapidly spread throughout the country. We have obtained data on esterase loci polymorphisms (Est2 and Est3), and analyzed them, using Landscape Shape Interpolation and the Monmonier Maximum Difference Algorithm to discover how regional invasion occurred. Hence, it was apparent that Z. indianus, after first arriving in São Paulo state, spread throughout the country, probably together with the transportation of commercial fruits by way of the two main Brazilian freeways, BR 153, to the south and the surrounding countryside, and the BR 116 along the coast and throughout the north-east
Polaritonic molecular clock for all-optical ultrafast imaging of wavepacket dynamics without probe pulses
Conventional approaches to probing ultrafast molecular dynamics rely on the use of synchronized laser pulses with a well-defined time delay. Typically, a pump pulse excites a molecular wavepacket. A subsequent probe pulse can then dissociate or ionize the molecule, and measurement of the molecular fragments provides information about where the wavepacket was for each time delay. Here, we propose to exploit the ultrafast nuclear-position-dependent emission obtained due to large light–matter coupling in plasmonic nanocavities to image wavepacket dynamics using only a single pump pulse. We show that the time-resolved emission from the cavity provides information about when the wavepacket passes a given region in nuclear configuration space. This approach can image both cavity-modified dynamics on polaritonic (hybrid light–matter) potentials in the strong light–matter coupling regime and bare-molecule dynamics in the intermediate coupling regime of large Purcell enhancements, and provides a route towards ultrafast molecular spectroscopy with plasmonic nanocavitiesThis work has been funded by the European Research Council grant ERC-2016-STG-714870 and the Spanish Ministry for Science, Innovation, and Universities—AEI grants RTI2018-099737-B-I00, PCI2018-093145 (through the QuantERA program of the European Commission), and CEX2018-000805-M (through the María de Maeztu program for Units of Excellence in R&D
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