Nutrition knowledge and competitiveness : interrelationships in high school wrestlers and their coaches

The purpose of the present investigation was to determine the level of nutrition knowledge and degree of competitiveness in high school wrestlers and their coaches and to look at the differences between groups. Twelve schools participated in the study and a total of 180 wrestlers and 29 coaches (12 head and 17 assistant) completed the nutrition knowledge and Sports Orientation (competitiveness) questionnaires. The results indicate that nutrition knowledge increases significantly with increasing age or grade level in the athletes (p=.0001), but significant increases were not seen for each year. The mean score for nutrition knowledge was 53.9% for the athletes and 67% for the coaches, both very low scores overall when compared with previous research, indicating a strong need for improved nutrition education in both populations. The coaches' mean nutrition knowledge levels were found to increase significantly with increasing years of coaching (p=.0001), suggesting that some knowledge is gained through experience. Team nutrition scores varied significantly, with a range of 50 to 63%, suggesting that some schools may have higher quality nutrition education programs than others. Results of the nutrition knowledge scores also demonstrate that a significant similarity exists between the head coaches' nutrition score and the teams' mean score (p=.0001), suggesting the possibility that the head coaches can have a greater impact on their teams' level of nutrition information than can other possible sources. Competitiveness scores were very high for this population as compared to previous studies completed with high school students, with the mean scores being 58.5 out of a possible 65 points for the wrestlers, and 59.4 for the coaches. Average competitiveness scores previously seen in the high school athletic population are approximately 20% lower than the scores found in these wrestlers, with a mean of 47. Competitiveness was found to significantly increase with increasing years of participation in wrestling (p=.02), but no other significant interrelationships were found to exist with regard to competitiveness levels in this population. There are many factors that were unable to be researched in this study due to inconsistent weight records that were to be kept by each team. Not 1 of the 12 schools kept consistent nor complete weight records throughout the season, making much of the planned research impossible. In conclusion, there exists much speculation regarding the possible consequences of weight cutting during adolescence, especially when the perceived benefits of the practice are not scientifically based. Research has suggested that there are many changes that need to be considered within the sport of wrestling such as minimal weight standards along with strict enforcement of those standards. As demonstrated with the results of this study, nutrition knowledge is low in the wrestling population, wrestlers and coaches alike, and therefore, additional education regarding nutrition and unsafe weight loss practices in high-risk populations such as the high school wrestler is needed

Knockout of 5-Lipoxygenase Results in Age-Dependent Anxiety-Like Behavior in Female Mice

The enzyme 5-lipoxygenase (5LO) has been implicated in a variety of neurological and psychiatric disorders including anxiety. Knockout of 5LO has previously been shown to alter anxiety-like behavior in mice at a young age but the effect of 5LO knockout on older animals has not been characterized.Here we used the elevated plus maze behavioral paradigm to measure anxiety-like behavior in female mice lacking 5LO (5LO-KO) at three different ages. Adolescent 5LO-KO animals did not significantly differ from wild-type (WT) animals in anxiety-like behavior. However, adult and older mice exhibited increased anxiety-like behavior compared to WT controls.These results indicate that 5LO plays a role in the development of the anxiety-like phenotype in an age-dependent manner in female mice. Future work should further investigate this interaction as 5LO may prove to be an important molecular target for the development of novel anxiolytic therapies

A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes

Identification of sequence variants robustly associated with predisposition to diabetic kidney disease (DKD) has the potential to provide insights into the pathophysiological mechanisms responsible. We conducted a genome-wide association study (GWAS) of DKD in type 2 diabetes (T2D) using eight complementary dichotomous and quantitative DKD phenotypes: the principal dichotomous analysis involved 5,717 T2D subjects, 3,345 with DKD. Promising association signals were evaluated in up to 26,827 subjects with T2D (12,710 with DKD). A combined (T1D+T2D) GWAS was performed using complementary data available for subjects with T1D, which, with replication samples, involved up to 40,340 diabetic subjects (and 18,582 DKD cases). Analysis of specific DKD phenotypes identified a novel signal near GABRR1 (rs9942471, p=4.5×10-8) associated with 'microalbuminuria' in European T2D cases. However, no replication of this signal was observed in Asian subjects with T2D, or in the equivalent T1D analysis. There was only limited support, in this substantially enlarged analysis, for association at previously-reported DKD signals, except for those at UMOD and PRKAG2, both associated with 'EGFR'. We conclude that, despite challenges in addressing phenotypic heterogeneity, access to increased sample sizes will continue to provide more robust inference regarding risk-variant discovery for DKD.</p

Understanding acute ankle ligamentous sprain injury in sports

This paper summarizes the current understanding on acute ankle sprain injury, which is the most common acute sport trauma, accounting for about 14% of all sport-related injuries. Among, 80% are ligamentous sprains caused by explosive inversion or supination. The injury motion often happens at the subtalar joint and tears the anterior talofibular ligament (ATFL) which possesses the lowest ultimate load among the lateral ligaments at the ankle. For extrinsic risk factors to ankle sprain injury, prescribing orthosis decreases the risk while increased exercise intensity in soccer raises the risk. For intrinsic factors, a foot size with increased width, an increased ankle eversion to inversion strength, plantarflexion strength and ratio between dorsiflexion and plantarflexion strength, and limb dominance could increase the ankle sprain injury risk. Players with a previous sprain history, players wearing shoes with air cells, players who do not stretch before exercising, players with inferior single leg balance, and overweight players are 4.9, 4.3, 2.6, 2.4 and 3.9 times more likely to sustain an ankle sprain injury. The aetiology of most ankle sprain injuries is incorrect foot positioning at landing – a medially-deviated vertical ground reaction force causes an explosive supination or inversion moment at the subtalar joint in a short time (about 50 ms). Another aetiology is the delayed reaction time of the peroneal muscles at the lateral aspect of the ankle (60–90 ms). The failure supination or inversion torque is about 41–45 Nm to cause ligamentous rupture in simulated spraining tests on cadaver. A previous case report revealed that the ankle joint reached 48 degrees inversion and 10 degrees internal rotation during an accidental grade I ankle ligamentous sprain injury during a dynamic cutting trial in laboratory. Diagnosis techniques and grading systems vary, but the management of ankle ligamentous sprain injury is mainly conservative. Immobilization should not be used as it results in joint stiffness, muscle atrophy and loss of proprioception. Traditional Chinese medicine such as herbs, massage and acupuncture were well applied in China in managing sports injuries, and was reported to be effective in relieving pain, reducing swelling and edema, and restoring normal ankle function. Finally, the best practice of sports medicine would be to prevent the injury. Different previous approaches, including designing prophylactice devices, introducing functional interventions, as well as change of games rules were highlighted. This paper allows the readers to catch up with the previous researches on ankle sprain injury, and facilitate the future research idea on sport-related ankle sprain injury