Hématome spontané de la surrénale (à propos de 2 cas)

L’hématome spontané de la surrénale est rare et d’étiologies multiples. Il est caractérisé par sa latence clinique et prête à confusion à une tumeur maligne de la surrénale. Nous rapportons deux observations: la première concernant un patient de 77 ans, sans antécédents pathologiques, qui a consulté pour des douleurs abdominales isolées. L’échographie et la tomodensitométrieont révélé l’existence d’une masse hétérogène aux dépens de la surrénale droite. La deuxième observation concerne une femme de 31 ans ayant consulté pour lombalgies gauches intermittentes. L’échographie et la tomodensitométrie ont révélé une tumeur kystique de la surrénale gauche.Dans les deux cas le bilan biologique était normal et une surrénalectomie par voie sous-costale a été réalisée. L’étude anatomopathologique a conclu à un hématome surrénalien sans lésion tumorale associée. Les aspects diagnostiques et thérapeutiques sont discutés

Verifying the reliability of hybrid issued from the cross “Picholine marocaine clones X Picholine du Languedoc”

In order to verify the reliability of hybrid population issued from crossing between 3 clones of "Picholine marocaine" cultivar and the "Picholine du Languedoc" cultivar, the descendants and their parents wereanalysed using 35 microsatellite loci. No offspring resulted from self crossing of "Picholine marocaine" cultivar and 218 descendants among 220 analysed are legitimate. This study showed clearly a segregating population and may be used as a genetic material for linkage map construction and for phenotyping resistance traits related to Spilocaea oleagina disease

Tumeurs des deux surrénales. A propos d’un cas

Les tumeurs surrénaliennes bilatérales sont rares. Nous rapportons un cas de phéochromocytome surrénalien associé à un corticosurrénalome controlatéral chez une patiente de 65 ans. L’association d’une hypertension artérielle à des céphalées, sueurs, et palpitations a orienté vers le diagnostic de phéochromocytome. Le bilan biologique basé sur le dosage urinaire des dérivés méthoxylés a confirmé ce diagnostic. L’échographie et le scanner ont montré la présence de deux massessurrénaliennes bilatérales de structure tissulaire. Les deux masses sont discrètement rehaussées après injection du produit de contraste. Devant ce tableau clinique, biologique et morphologique, le diagnostic de phéochromocytome surrénalien bilatéral est retenu. Par conséquent unesurrénalectomie bilatérale par voie bi-sous-costale a été réalisée. L’examen anatomopathologique a révélé la coexistence d’un phéochromocytome sur la pièce de surrénalectomie droite et d’un carcinome corticosurrénalien sur la pièce de surrénalectomie gauche, ce qui était imprévu. Les suites opératoires ont été bonnes, sans récidive, avec un recul de 4 ans. A la lumière de cette observation et d’une revue de la littérature, nous discutons les différentes  caractéristiques de cetteassociation inhabituelle

EFFECTS OF MAGNETIC AND NON MAGNETIC LAYER THICKNESS ON GIANT MAGNETORESISTANCE IN (NiFeCo/Cu) MULTILAYERS

This paper presents a study of the magnetoresistance (MR) in the layered magnetic structure (NiFeCo/Cu). The effect of the magnetic (m) and non magnetic (nm) layer thickness (tm , tnm) and the composition of the magnetic layer has been discussed in the framework of the Johnson-Camley semiclassical approach, which is based on the Boltzmann transport equation. Our results are compared with the experiments and seem to show good agreement. Indeed, three main features of the MR are reproduced: (i) Presence of MR peak at tmmax which vary with the magnetic layer composition, (ii) A MR decrease with non magnetic layer thickness tnm, (iii) The increasing magnitude of MR ratio with increasing Co content.This paper presents a study of the magnetoresistance (MR) in the layered magnetic structure (NiFeCo/Cu). The effect of the magnetic (m) and non magnetic (nm) layer thickness (tm , tnm) and the composition of the magnetic layer has been discussed in the framework of the Johnson-Camley semiclassical approach, which is based on the Boltzmann transport equation. Our results are compared with the experiments and seem to show good agreement. Indeed, three main features of the MR are reproduced: (i) Presence of MR peak at tmmax which vary with the magnetic layer composition, (ii) A MR decrease with non magnetic layer thickness tnm, (iii) The increasing magnitude of MR ratio with increasing Co content

Dependence of magnetoresistive properties in [Co98Zr2 (25Å)/Cu/Co (25Å)] magnetic sandwiches on the Cu deposition pressure: Correlation of the “CoZrCu” disordered phase concentration and the interfacial mixed zone thickness with the Cu pressure

The magnetoresistance (MR) and the saturation resistivity (ρs) are studied versus the Cu deposition pressure (PCu) at room temperature, in [Co98Zr2 (25Å)/Cu (tCu) /Co (25Å)] magnetic sandwiches prepared by RF diode sputtering. Results of low angle X-Ray Diffraction patterns have been proved the importante interfacial degradation observed in (CoZr/Cu) multilayers, compared to the usual (Co/Cu) structures. The highest value of transverse MR is obtained along the easy axis, and the MR curve saturates in a small magnetic field of 100 Oe at room temperature. Which leads to an interesting increase in MR sensitivity about 2%/Oe. The main features of the magnetoresistive properties evolution with Cu deposition pressure are: The maximum of MR increases and moves towards larger Cu thicknesses (tCu) for increasing PCu. The saturation resistivity ρs decreases with increasing tCu while it increases versus PCu. The satisfactory agreement between our experimental results and calculated ones in the framework of the Johnson-Camley semi-classical model, allows us to interpret the MR and ρs behavior as a result of a reinforcement of the disordered phase ″CoZrCu″ inside the mixed zone whose thickness tmx increases with PCu .The magnetoresistance (MR) and the saturation resistivity (ρs) are studied versus the Cu deposition pressure (PCu) at room temperature, in [Co98Zr2 (25Å)/Cu (tCu) /Co (25Å)] magnetic sandwiches prepared by RF diode sputtering. Results of low angle X-Ray Diffraction patterns have been proved the importante interfacial degradation observed in (CoZr/Cu) multilayers, compared to the usual (Co/Cu) structures. The highest value of transverse MR is obtained along the easy axis, and the MR curve saturates in a small magnetic field of 100 Oe at room temperature. Which leads to an interesting increase in MR sensitivity about 2%/Oe. The main features of the magnetoresistive properties evolution with Cu deposition pressure are: The maximum of MR increases and moves towards larger Cu thicknesses (tCu) for increasing PCu. The saturation resistivity ρs decreases with increasing tCu while it increases versus PCu. The satisfactory agreement between our experimental results and calculated ones in the framework of the Johnson-Camley semi-classical model, allows us to interpret the MR and ρs behavior as a result of a reinforcement of the disordered phase ″CoZrCu″ inside the mixed zone whose thickness tmx increases with PCu

Giant magnetoresistance in (Ni 80 Fe 20 /Cu) multilayers

The dependence of the magnetoresistance (MR) ratio on the thicknesses of the magnetic (m) and non magnetic (nm) layers is studied for Ni80Fe20 /Cu soft magnetic multilayers with a fixed number of bilayers (12). The highest value of the MR is 17,3% at Cu layer thickness of 7 Å. Very high sensitivity, around 132%/kOe has been observed. We present a discussion of the MR results using the Johnson-Camley semiclassical model based on the Boltzmann transport equation.The dependence of the magnetoresistance (MR) ratio on the thicknesses of the magnetic (m) and non magnetic (nm) layers is studied for Ni80Fe20 /Cu soft magnetic multilayers with a fixed number of bilayers (12). The highest value of the MR is 17,3% at Cu layer thickness of 7 Å. Very high sensitivity, around 132%/kOe has been observed. We present a discussion of the MR results using the Johnson-Camley semiclassical model based on the Boltzmann transport equation

Mélanome endobronchique

Le mélanome malin a un potentiel métastatique important. Les métastases pulmonaires du mélanome sont communes cependant la localisation endobronchique reste rare et pose le problème de son origine primitive ou secondaire. Nous rapportons le cas d’un mélanome pulmonaire qui présente des particularités intéressantes: une lésion cutanée présumée primitive totalement régressive, la présentation radio clinique mimant parfaitement un cancer bronchique primitif, un aspect endoscopique bourgeonnant et grisâtre dont l’étude histologique a permis de poser le diagnostic, une agressivité tumorale avec une extension intracardiaque et bourgeon tumoral intra cavitaire. A travers cette observation, les auteurs étudient les caractéristiques radio-cliniques pouvant distinguer le mélanome pulmonaire primitif du secondaire; la localisation endobronchique avec une revue de la littérature sur les métastases endo bronchiques; le bilan d’extension à entamer en cas de mélanome pulmonaire ainsi que les difficultés thérapeutiques posés par ce type de lésion dont le pronostic reste péjoratif

Urine E-cadherin: A Marker for early detection of kidney injury in diabetic patients.

Diabetic nephropathy (DN) is the main reason for end-stage renal disease. Microalbuminuria as the non-invasive available diagnosis marker lacks specificity and gives high false positive rates. To identify and validate biomarkers for DN, we used in the present study urine samples from four patient groups: diabetes without nephropathy, diabetes with microalbuminuria, diabetes with macroalbuminuria and proteinuria without diabetes. For the longitudinal validation, we recruited 563 diabetic patients and collected 1363 urine samples with the clinical data during a follow-up of 6 years. Comparative urinary proteomics identified four proteins Apolipoprotein A-I (APOA1), Beta-2-microglobulin (B2M), E-cadherin (CDH1) and Lithostathine-1-alpha (REG1A), which differentiated with high statistical strength (p < 0.05) between DN patients and the other groups. Label-free mass spectrometric quantification of the candidates confirmed the discriminatory value of E-cadherin and Lithostathine-1-alpha (p < 0.05). Immunological validation highlighted E-cadherin as the only marker able to differentiate significantly between the different DN stages with an area under the curve (AUC) of 0.85 (95%-CI: [0.72, 0.97]). The analysis of the samples from the longitudinal study confirmed the prognostic value of E-cadherin, the critical increase in urinary E-cadherin level was measured 20 ± 12.5 months before the onset of microalbuminuria and correlated significantly (p < 0.05) with the glomerular filtration rate measured by estimated glomerular filtration rate (eGFR)