ВЛИЯНИЕ ВИДА СРЕДНЕЙ ВЗВЕШЕННОЙ ОЦЕНКИ НА ЗАВИСИМОСТЬ КОМПЛЕКСНОГО ПОКАЗАТЕЛЯ КАЧЕСТВА ОТ ПАРАМЕТРОВ ОБЪЕКТА

Objects quality is usually assessed by a complex indicator. It includes single quality indicators with their significance factors. The convolution of the corresponding dependencies represents average weighted quantities: arithmetic, geometric, harmonic, quadratic, etc. At the same time, the influence of the convolution type on the level of the complex quality index, the stability of the calculation results and, the reliability of the quality comparison among a number of similar objects is unknown in advance. Therefore, the aim of the study was to assess the influence of the average weighted type on the level and stability of the calculating results of the complex quality index in different objects compressing.For typical private objects compared the values of the complex quality index calculated according to the formulas of various average weighted estimates. Significance of the corresponding unit quality indicators, incompleteness of the object description and control factors influence on the object took into account.The results of the research were got using the method of virtual experiment planning. They showed that the influencing parameters changes, the calculated levels and stability of the complex quality index essentially depend on the type of convolution. It was shown that under the priori uncertainty of the necessary convolution for the best representative choosing of the corresponding class of objects, the arithmetic average weighted estimate is the best for using.The obtained data can serve as a basis for an informed choice of the type of average weighted in the quality assessment of various objects and decision-making on rational levels of controlled factors.Качество объектов обычно оценивают соответствующим комплексным показателем. Он формируется единичными показателями качества с их коэффициентами значимости. Свертку соответствующих зависимостей представляют средними взвешенными величинами: арифметической, геометрической, гармонической, квадратической и др. При этом заранее неизвестным является влияние вида свертки на уровень комплексного показателя качества, стабильность результатов расчета и достоверность сопоставления качества сходных объектов. Поэтому целью исследования являлась оценка влияния вида среднего взвешенного на уровень и стабильность результатов расчета комплексного показателя качества при сравнении различных объектов.Для типичных частных объектов сопоставили рассчитанные значения комплексного показателя качества с использованием формул указанных средних взвешенных оценок. При этом учли значимости соответствующих единичных показателей качества, показатель неполноты описания объекта и влияние на объект управляющих факторов.Результаты расчетов получили с применением планирования виртуального эксперимента. Они показали, что уровень и стабильность комплексного показателя качества существенно зависят от вида свертки. В результате выявили, что при выборе лучшего представителя из соответствующего класса объектов целесообразно пользоваться средней арифметической взвешенной оценкой.Полученные данные могут служить основой при выборе вида среднего взвешенного при оценке качества разнообразных объектов и принятии решений о рациональных уровнях управляемых факторов

Establishment of an ES Cell-Derived Murine Megakaryocytic Cell Line, MKD1, with Features of Primary Megakaryocyte Progenitors

Because of the scarcity of megakaryocytes in hematopoietic tissues, studying megakaryopoiesis heavily relies on the availability of appropriate cellular models. Here, we report the establishment of a new mouse embryonic stem (ES) cell-derived megakaryocytic cell line, MKD1. The cells are factor-dependent, their cell surface immunophenotype and gene expression profile closely resemble that of primary megakaryocyte progenitors (MkPs) and they further differentiate along the megakaryocyte lineage upon valproic acid treatment. At a functional level, we show that ablation of SCL expression, a transcription factor critical for MkP maturation, leads to gene expression alterations similar to that observed in primary, Scl-excised MkPs. Moreover, the cell line is amenable to biochemical and transcriptional analyses, as we report for GpVI, a direct target of SCL. Thus, the MKD1 cell line offers a pertinent experimental model to study the cellular and molecular mechanisms underlying MkP biology and more broadly megakaryopoiesis

INFLUENCE OF THE AVERAGE WEIGHTED ESTIMATION TYPE ON THE DEPENDENCE OF THE COMPLEX QUALITY INDEX ON THE PARAMETERS OF OBJECT

Objects quality is usually assessed by a complex indicator. It includes single quality indicators with their significance factors. The convolution of the corresponding dependencies represents average weighted quantities: arithmetic, geometric, harmonic, quadratic, etc. At the same time, the influence of the convolution type on the level of the complex quality index, the stability of the calculation results and, the reliability of the quality comparison among a number of similar objects is unknown in advance. Therefore, the aim of the study was to assess the influence of the average weighted type on the level and stability of the calculating results of the complex quality index in different objects compressing.For typical private objects compared the values of the complex quality index calculated according to the formulas of various average weighted estimates. Significance of the corresponding unit quality indicators, incompleteness of the object description and control factors influence on the object took into account.The results of the research were got using the method of virtual experiment planning. They showed that the influencing parameters changes, the calculated levels and stability of the complex quality index essentially depend on the type of convolution. It was shown that under the priori uncertainty of the necessary convolution for the best representative choosing of the corresponding class of objects, the arithmetic average weighted estimate is the best for using.The obtained data can serve as a basis for an informed choice of the type of average weighted in the quality assessment of various objects and decision-making on rational levels of controlled factors

Personnel Qualimetric Assessment of the Consumer Information CENTER of Insurance Organization

The object of the study was the system for assessing the quality of the information service personnel of the insurance company. When determining the approaches to improving the relevant components of the quality system, the organization took into account that the personnel assessment process is the most painstaking, complex and lengthy aspect of the firm's activities. Mistakes in such a matter can not only cost one person's dissatisfaction, but affect a certain number of problems regarding the stable functioning of an entire institution. The complexity of this issue lies in the absence, in general, of universal quantitative assessment criteria and the strong influence of the «human factor», which necessitates the use of expert qualimetric approaches with an increase in the objectivity of the assessment. In this regard, the work was aimed at developing an objective system for assessing personnel on the example of the information service of one of the insurance companies in Ukraine using qualimetric methods. Tools for the integrated qualimetric assessment of the quality of the information center employees' activities, which consist in determining of the appropriate list and significance of the personnel performance quality indicators, were proposed with an analysis of the possibility of their identification and measurement. Additionally, it is recommended to take into account independent control using «mystery shopper», as well as the self-esteem of workers. The obtained results were used in the development of the Methodology (Procedure) of the quality system for the assessment of activities and personnel certification. The use of the outlined approaches makes it possible to increase the level of satisfaction of customers and consumers of insurance services, to increase the economic efficiency of the organization's activities, to differentiate personnel by the quality of work with appropriate personal encouragement for training, self-realization and work productivity. The deliverables may be useful to organizations in the relevant domain and may be applicable in other similar settings