119 research outputs found
What inspires young people to study physics? Results from the WG1 interviews survey
The talk will focus on the main results of an Interview based Survey of 1st Year University Physics Students, carried out within Working Group 1 (WG1) of the HOPE project. Among the HOPE activities, 112 interviews have been conducted in 16 universities, in order to investigate in some depth the factors that inspire young people to study physics and to identify possible critical factors which can produce the dropping out.The individual interviews have been carried out on a selection of students who had previously answered the WG1 Questionnaire on the inspirational factors, led by Gareth Jones from the Imperial College, London. In the talk, we will show how the interviews helped us to unpack the main results achieved with the questionnaire survey. In particular, we will present a comprehensive picture of \u201ccuriosity\u201d which turned out to be the predominant motivating factor and we will show how the interviews can throw extra light on reasons for comparatively low scores for factors like (i) enhancing employment prospects, (ii) effect of physics teacher, (iii) scientists in the family
Student interviews on inspirational and drop-out factors progress report (Sub-Group WG1-B)
Progress report on the survey on inspirational and drop-out factors we carried out, within the activities of WG1, through individual interviews to physics students. In particular, we present: 1) the research groups involved in the survey and in the data analysis; 2) the sample; 3) the research questions; 4) the quantitative and qualitative research methods of data analysis we are designing; 4) the preliminary analysis and the problematic issues we are dealing with; 5) discussion, implications and future plans
Environnements multimédias pour l'étude de la physique
Dans cet article, nous présentons une proposition
didactique fondée sur l'utilisation de simulations reconstruisant des
expériences originelles particulièrement importantes dans
l'histoire de la physique. Nous avons choisi des simulations relatives Ă
des concepts fondamentaux de la statique des fluides, les expériences de
Boyle sur la compression et la dilatation de l'air. Les simulations ont
été insérées dans un contexte
multimédia et hypertextuel réalisé afin de satisfaire aux
exigences survenues au cours des essais successifs avec des Ă©tudiants de
17-20 ans
Un modèle pour la compréhension des propriétés des liquides
Cet article présente une proposition didactique visant
à favoriser la compréhension des concepts physiques relatifs
Ă l'hydrostatique et en particulier au principe de Pascal. La proposition,
qui est insérée dans un contexte d'hypertexte, se fonde sur
l'utilisation d'un modèle qui rend compte des propriétés
fondamentales d'un liquide, comme son action sur les parois du récipient
qui le contient ou la transmission isotrope des forces qui s'exercent sur lui. Les
affinements successifs du modèle permettent d'aboutir à la
définition de la pression dans les liquides
Studying colours with a smartphone
We show how a low-cost spectrometer, based on the use of inexpensive diffraction transmission gratings coupled with a smartphone photo camera, can be assembled and employed to obtain quantitative measurements of spectra from different sources. The analysis of spectra emitted by different light sources (incandescent bulb, fluorescent lamp, gas lamps, LEDs) helps students understand the different physical mechanisms which govern the production of light. Measurements of emission and transmission spectra allow students to focus on the differences between additive and subtractive models of colour formation. For this purpose the spectra of RGB colours emitted from an LCD screen and the transmission spectra of CMY pigments of a laser printer have been studied, using our low-cost spectroscope. A sequence of experimental activities was designed, and proposed to undergraduate students and secondary school teachers in order to study the feasibility and educational potential
Understanding first-year students’ curiosity and interest about physics : Lessons learned from the HOPE project
This paper focuses on results of an interview based survey of first-year university physics students, carried out within the EU Horizons in Physics Education (HOPE) project (http://hopenetwork.eu/). 94 interviews conducted in 13 universities have been analyzed to investigate the factors that inspire young people to study physics. In particular, the main motivational factor, which was proven to consist of personal interest and curiosity, was unfolded into different categories and detailed interest profiles were produced. The results are arguably useful to help academic curriculum developers and teaching personnel in physics departments to provide guidance to students in developing and focusing their interest towards specific sub-fields and/or to design targeted recruitment and outreach initiatives.Peer reviewe
Bordetella bronchiseptica Diguanylate Cyclase BdcA Regulates Motility and Is Important for the Establishment of Respiratory Infection in Mice
Bacteria can be motile and planktonic or, alternatively, sessile and participating in the biofilm mode of growth. The transition between these lifestyles can be regulated by a second messenger, cyclic dimeric GMP (c-di-GMP). High intracellular c-diGMP concentration correlates with biofilm formation and motility inhibition in most bacteria, including Bordetella bronchiseptica, which causes respiratory tract infections in mammals and forms biofilms in infected mice. We previously described the diguanylate cyclase BdcA as involved in c-di-GMP synthesis and motility regulation in B. bronchiseptica; here, we further describe the mechanism whereby BdcA is able to regulate motility and biofilm formation. Amino acid replacement of GGDEF with GGAAF in BdcA is consistent with the conclusion that diguanylate cyclase activity is necessary for biofilm formation and motility regulation, although we were unable to confirm the stability of the mutant protein. In the absence of the bdcA gene, B. bronchiseptica showed enhanced motility, strengthening the hypothesis that BdcA regulates motility in B. bronchiseptica.
We showed that c-di-GMP-mediated motility inhibition involved regulation of flagellin expression, as high c-di-GMP levels achieved by expressing BdcA significantly reduced the level of flagellin protein. We also demonstrated that protein BB2109 is necessary for BdcA activity, motility inhibition, and biofilm formation. Finally, absence of the bdcA gene affected bacterial infection, implicating BdcA-regulated functions as important for bacterium-host interactions. This work supports the role of c-di-GMP in biofilm formation and motility regulation in B. bronchiseptica, as well as its impact on pathogenesis.Instituto de Biotecnologia y Biologia Molecula
Evidences of accumulation points in cascade regenerative phenomena observed in high voltage dc devices insulated by long vacuum gaps
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Inhibition of the Nicotinic Acetylcholine Receptors by Cobra Venom α-Neurotoxins: Is There a Perspective in Lung Cancer Treatment?
Nicotine exerts its oncogenic effects through the binding to nicotinic acetylcholine receptors (nAChRs) and the activation of downstream pathways that block apoptosis and promote neo-angiogenesis. The nAChRs of the α7 subtype are present on a wide variety of cancer cells and their inhibition by cobra venom neurotoxins has been proposed in several articles and reviews as a potential innovative lung cancer therapy. However, since part of the published results was recently retracted, we believe that the antitumoral activity of cobra venom neurotoxins needs to be independently re-evaluated
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