Turbulent Contributions to Ohm's Law in Axisymmetric Magnetized Plasmas

The effect of magnetic turbulence in shaping the current density in axisymmetric magnetized plasma is analyzed using a turbulent extension of Ohm's law derived from the self-consistent action-angle transport theory. Besides the well-known hyper-resistive (helicity-conserving) contribution, the generalized Ohm's law contains an anomalous resistivity term, and a turbulent bootstrap-like term proportional to the current density derivative. The numerical solution of the equation for equilibrium and turbulence profiles characteristic of conventional and advanced scenarios shows that, trough "turbulent bootstrap" effect and anomalous resistivity turbulence can generate power and parallel current which are a sizable portion (about 20-25%) of the corresponding effects associated with the neoclassical bootstrap effect. The degree of alignment of the turbulence peak and the pressure gradient plays an important role in defining the steady-state regime. In fully bootstrapped tokamak, the hyper-resistivity is essential in overcoming the intrinsic limitation of the hollow current profile.Comment: 19 pages, 6 figures, journal pape

Editorial. The sustainability challenge. New perspectives on the use of microbial approaches and their impact on food and feed

Building a more resilient food chain, reducing food loss and waste, improving food production practices and increasing plant-based food consumption are some of the fundamental actions suggested in The Sustainable Development Goals adopted by the United Nations Member States in 20151. The objective of this special issue was to explore how the use of microorganisms as direct or indirect sources of transformation could contribute to these sustainability practices. In this context, the following strategies have been presented: (i) valorization of side-streams and underutilized food resources via fermentation, (ii) improvement of the efficiency of bioprocesses for the food and feed industry, and (iii) understanding and applying the microbiome as a resource to improve the agro-food system

I processi di aging e il loro impatto sulle proprietà del Nitinol superelastico

Nel corso degli ultimi anni il crescente interesse riguardo ai processi di aging sul Nitinol ha portato i ricercatoria concentrarsi sulla precipitazione indotta di fasi secondarie e sull’effetto che esse possono avere sulcomportamento termo-meccanico e sulla resistenza a fatica. Un trattamento di aging non sufficientementeintenso da indurre la precipitazione può comunque dar luogo a fenomeni secondari in grado di impattare inmaniera significativa sulle osservabili di interesse. In questo lavoro sono stati analizzati gli effetti generati da unalieve ricottura secondaria sulle proprietà di fili superelastici in lega NiTi (Ø0.3mm, lega Ti-50.8Ni at.%). Sono statistudiati più di trenta differenti trattamenti termici, mediante i quali è stato possibile modulare le temperature ditrasformazione osservando in particolare le variazioni delle trasformazioni M?R, R?A, della loro spaziatura,dell’isteresi e della caratteristica superelastica. Una volta selezionati i campioni con proprietà ancora in accordocon i requisiti richiesti dal settore biomedico, ne è stata valutata la resistenza a fatica mediante il test di flessionerotante ed in seguito confrontata con le prestazioni di un materiale standard

“Bit Standard”- Bitcoin between reality and risks of a “halfway-money”

This work provides an explanation of the market underlying the evolution due to modern technologies and technical advances, especially in transactions. In this regard, the authors specify the aspect related to the creation of virtual currencies like bitcoin that can circulate thanks to the Blockchain system through miners\u2019 work. The authors consider areas related to the warnings on the use and exchange of virtual currencies. The aim is to conceptualize in a graphical way the current operational transaction in bitcoin through the existing exchange platforms. The authors try to attest the fickleness of the disintermediation ideal founding Bitcoin. The analysis purposed could be interesting and useful to provide a kind of interpretation of the phenomenon and a general overview about Bitcoin system

Droplets generated from toilets during urination as a possible vehicle of carbapenem-resistant Klebsiella pneumoniae

BACKGROUND: In the health care setting, infection control actions are fundamental for containing the dissemination of multidrug-resistant bacteria (MDR). Carbapenemase-producing Enterobacterales (CPE), especially Klebsiella pneumoniae (CR-KP), can spread among patients, although the dynamics of transmission are not fully known. Since CR-KP is present in wastewater and microorganisms are not completely removed from the toilet bowl by flushing, the risk of transmission in settings where toilets are shared should be addressed. We investigated whether urinating generates droplets that can be a vehicle for bacteria and explored the use of an innovative foam to control and eliminate this phenomenon. METHODS: To study droplet formation during urination, we set up an experiment in which different geometrical configurations of toilets could be reproduced and customized. To demonstrate that droplets can mobilize bacteria from the toilet bowl, a standard ceramic toilet was contaminated with a KPC-producing Klebsiella pneumoniae ST101 isolate. Then, we reproduced urination and attached culture dishes to the bottom of the toilet lid for bacterial colony recovery with and without foam. RESULTS: Rebound droplets invariably formed, irrespective of the geometrical configuration of the toilet. In microbiological experiments, we demonstrated that bacteria are always mobilized from the toilet bowl (mean value: 0.11 ± 0.05 CFU/cm2) and showed that a specific foam layer can completely suppress mobilization. CONCLUSIONS: Our study demonstrated that droplets generated from toilets during urination can be a hidden source of CR-KP transmission in settings where toilets are shared among colonized and noncolonized patients

State of the art in advanced endoscopic imaging for the detection and evaluation of dysplasia and early cancer of the gastrointestinal tract

Ideally, endoscopists should be able to detect, characterize, and confirm the nature of a lesion at the bedside, minimizing uncertainties and targeting biopsies and resections only where necessary. However, under conventional white-light inspection – at present, the sole established technique available to most of humanity – premalignant conditions and early cancers can frequently escape detection. In recent years, a range of innovative techniques have entered the endoscopic arena due to their ability to enhance the contrast of diseased tissue regions beyond what is inherently possible with standard white-light endoscopy equipment. The aim of this review is to provide an overview of the state-of-the-art advanced endoscopic imaging techniques available for clinical use that are impacting the way precancerous and neoplastic lesions of the gastrointestinal tract are currently detected and characterized at endoscopy. The basic instrumentation and the physics behind each method, followed by the most influential clinical experience, are described. High-definition endoscopy, with or without optical magnification, has contributed to higher detection rates compared with white-light endoscopy alone and has now replaced ordinary equipment in daily practice. Contrast-enhancement techniques, whether dye-based or computed, have been combined with white-light endoscopy to further improve its accuracy, but histology is still required to clarify the diagnosis. Optical microscopy techniques such as confocal laser endomicroscopy and endocytoscopy enable in vivo histology during endoscopy; however, although of invaluable assistance for tissue characterization, they have not yet made transition between research and clinical use. It is still unknown which approach or combination of techniques offers the best potential. The optimal method will entail the ability to survey wide areas of tissue in concert with the ability to obtain the degree of detailed information provided by microscopic techniques. In this respect, the challenging combination of autofluorescence imaging and confocal endomicroscopy seems promising, and further research is awaited

Broadband adiabatic light transfer in optically induced waveguide arrays

We demonstrate experimentally the broadband and adiabatic light transfer in coupled waveguides based on multiple stimulated Raman adiabatic passage. Our experimental platform utilizes planar-type reconfigurable optically induced waveguide arrays and allows for efficient and robust transfer of light from an input waveguide over multiple states (up to nine) to an output waveguide. The same waveguide structures are tested for two propagation wavelengths separated by more than 200 nm, proving the achromaticity of the transfer process

Biosynthesis of γ-aminobutyric acid by lactic acid bacteria in surplus bread and its use in bread making

Aims: The aim of this study was to investigate the effectiveness of bread as substrate for γ-aminobutyric acid (GABA) biosynthesis, establishing a valorization strategy for surplus bread, repurposing it within the food chain. Methods and results: Surplus bread was fermented by lactic acid bacteria (LAB) to produce GABA. Pediococcus pentosaceus F01, Levilactobacillus brevis MRS4, Lactiplantibacillus plantarum H64 and C48 were selected among 33 LAB strains for the ability to synthesize GABA. Four fermentation experiments were set up using surplus bread as such, added of amylolytic and proteolytic enzymes, modifying the pH or mixed with wheat bran. Enzyme-treated slurries led to the release of glucose (up to 20 mg g-1 ) and free amino acid, whereas the addition of wheat bran (30% of bread weight) yielded the highest GABA content (circa 800 mg kg-1 of dry weight) and was the most suitable substrate for LAB growth. The selected slurry was ultimately used as an ingredient in bread making causing an increase in free amino acids. Conclusions: Besides the high GABA concentration (148 mg kg-1 dough), the experimental bread developed in this study was characterized by good nutritional properties, highlighting the efficacy of tailored bioprocessing technologies as means to mitigate food wastage. Significance and impact of study: Our results represent a proof of concept of effective strategies to repurpose food industry side streams

A Western single-center experience with endoscopic submucosal dissection for early gastrointestinal cancers

Endoscopic submucosal dissection (ESD) has gained worldwide acceptance as a treatment for early gastrointestinal cancers (EGICs). However, the management of these tumors in the Western world is still mainly surgical. Our aim was to evaluate the safety and feasibility of ESD at a European center. Based on the knowledge transferred by one of the most experienced Japanese institutions, we conducted a pilot study on 25 consecutive patients with EGICs located in the esophagus (n = 3), stomach (n = 7), duodenum (n = 1), and colon (n = 14) at our tertiary center over a 2-year-period. The main outcome measurements were complete (R0) resection, as well as en-bloc resection and the management of complications. The R0 and en-bloc resection rates were 100% and 84%, respectively. There were three cases of bleeding and five cases of perforation. With a median follow up of 18 months, two recurrences were observed. We conclude that ESD for early esophageal and gastric cancers is feasible and effective, while colonic ESD requires more expertise